Rivaroxaban versus vitamin K antagonist treatment on the progression of coronary calcification: the IRIVASC-trial
Robert Stöhr,
Sebastian Reinartz,
Timm Dirrichs
et al.
Abstract:Vitamin K antagonists (VKA) remain the only option of anticoagulation for people with mechanical valve replacement and due to their wider availability and lower acquisition costs, VKA’s remain widely used in low- and middle-income countries. It has been suggested that prolonged use of VKAs can increase the development of vascular and valvular calcification, though this effect has not been examined in larger randomized prospective trials. This investigator-initiated multicenter, prospective, randomized, open-la… Show more
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