Risperidone-induced fecal incontinence: A case report

Aygun, Berna

doi:10.14744/dajpns.2022.00172

Cited by 2 publications

(3 citation statements)

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“…For example, Herguner and Mukaddes [ 28 ] described double incontinence (fecal plus urinary incontinence) after 1 to 3 weeks of initiation of Risperidone treatment in two patients with autistic disorder; however, the reported side effects were not severe. In addition, there are several other case reports associating the use of Risperidone with urinary and fecal incontinence in cases of autistic spectrum disorder (ASD) [ 29 ], attention deficit hyperactivity disorder, and ODD [ 30 ]. In one of these studies, the researchers stated that the probability of such a complication is of 7 based on the Naranjo Adverse Drug Reaction Probability Scale, being graded as “probable” according to the scale’s definition [ 30 ].…”

Section: Discussionmentioning

confidence: 99%

“…In addition, there are several other case reports associating the use of Risperidone with urinary and fecal incontinence in cases of autistic spectrum disorder (ASD) [ 29 ], attention deficit hyperactivity disorder, and ODD [ 30 ]. In one of these studies, the researchers stated that the probability of such a complication is of 7 based on the Naranjo Adverse Drug Reaction Probability Scale, being graded as “probable” according to the scale’s definition [ 30 ]. Since retention behavior is central to the maintenance of constipation, fecal impaction, and retentive FI, the improvement in these factors in patients with psychiatric disorders could be associated with psychological and behavioral improvement and a change in body perception.…”

Section: Discussionmentioning

confidence: 99%

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Efficacy of atypical antipsychotics in the treatment of fecal incontinence in children and adolescents: a randomized clinical trial

Zahed,

Fatahi,

Tabatabaee

et al. 2024

BMC Pediatr

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Objectives Functional retentive overflow incontinence (retentive FI) is the most common cause of fecal soiling in children. Based on the clinical experiences, the treatment of retentive FI in patients with comorbid psychiatric disorders was accelerated when Risperidone was used as treatment for their psychiatric comorbidities; therefore, this study was conducted to evaluate the effect of risperidone in the treatment of retentive FI in children and adolescents. Methods In this double-blind, randomized, placebo-controlled trial, 140 patients aged 4–16 years eligible for the study were randomized into two groups, receiving either 0.25–0.5 mg of Risperidone syrup (n = 70) or maltodextrin syrup (placebo group, n = 70) every 12 h daily for 12 weeks. Sociodemographic data, including age, sex, weight, height, BMI, BMI z-score, and socioeconomic status, was recorded, and the number of nocturnal FI, diurnal FI, and painful defecations was measured. Results 136 participants (69 on Risperidone and 67 on placebo) were included in the study. Mean age of participants in the intervention and placebo groups were 7.2 ± 2.4 years and 8.0 ± 3.1 years, respectively. The mean number of nocturnal FI (Ptrend=0.39) and diurnal FI (Ptrend=0.48) in patients without psychiatric comorbidities, and the number of painful defecations for participants with and without psychiatric comorbidities (P = 0.49, P = 0.47, respectively) were not significantly different between the groups, but a significant effect was observed in diurnal FI after Risperidone treatment in patients with psychiatric comorbidities (P < 0.001). Conclusion Risperidone, when used along with other non-pharmacological interventions, may be helpful in treating FI in pediatric patients with psychiatric comorbidities.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Efficacy of atypical antipsychotics in the treatment of fecal incontinence in children and adolescents: a randomized clinical trial

Zahed,

Fatahi,

Tabatabaee

et al. 2024

BMC Pediatr

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“…To the Editor, Risperidone is an atypical antipsychotic commonly used in children and adolescents for aggression, behavioral issues, tic disorders, and psychotic disorders 1 . Although the use of risperidone is mostly safe in children, it may cause some side effects 1,2 . Risperidone may cause common side effects such as weight gain, sedation, constipation, dry mouth, dystonia, rigidity, and increased salivation 3 .…”

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confidence: 99%

Sekiz yaşında bir çocukta risperidona bağlı enürezis

ÜSTÜN

2023

Cukurova Medical Journal

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Risperidone is an antipsychotic commonly used in children and adolescents. The use of risperidone is mostly safe in children, but it can cause some side effects. Few cases of enuresis with risperidone have been reported in the literature so far, some of these cases have been associated with the use of antidepressants or other antipsychotics in combination with risperidone. We present an 8.5-year-old patient with enuresis with risperidone.

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Risperidone-induced fecal incontinence: A case report

Cited by 2 publications

References 0 publications

Efficacy of atypical antipsychotics in the treatment of fecal incontinence in children and adolescents: a randomized clinical trial

Efficacy of atypical antipsychotics in the treatment of fecal incontinence in children and adolescents: a randomized clinical trial

Sekiz yaşında bir çocukta risperidona bağlı enürezis

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