Risperidone-induced acute pancreatitis

Abstract

We report on an adolescent with Asperger's syndrome who developed acute pancreatitis during treatment with risperidone and citalopram. On discontinuation of psychopharmacotherapy, he fully recovered. A rechallenge testing of citalopram did not result in a relapse of pancreatitis. Other known causes of pancreatitis were not obvious. Clinicians should be alert to this rare adverse event in patients who exhibit symptoms of an acute abdominal disorder during risperidone treatment.

Acute alithiasic pancreatitis following the use of Risperidone in a young man with schizophrenia: As a rare case report

“…Although effective, they are associated with a high risk of metabolic and hematologic complications such as hyperglycemia, diabetes and agranulocytosis [5] , [6] , [7] . Reviewing the literature, only few cases of acute pancreatitis due to risperidone treatment have been reported, occurring mainly after short time use, and commonly related to lithiasic cause [8] , [9] , [10] .…”