2014
DOI: 10.1371/journal.pone.0086171
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Risky Drinking Patterns Are Being Continued into Pregnancy: A Prospective Cohort Study

Abstract: BackgroundRisky patterns of alcohol use prior to pregnancy increase the risk of alcohol-exposed pregnancies and subsequent adverse outcomes. It is important to understand how consumption changes once women become pregnant.ObjectiveThe aim of this study was to describe the characteristics of women that partake in risky drinking patterns before pregnancy and to examine how these patterns change once they become pregnant.MethodsA sample of 1577 women from the 1973–78 cohort of the Australian Longitudinal Study on… Show more

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Cited by 29 publications
(31 citation statements)
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References 39 publications
(54 reference statements)
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“…This pattern of alcohol exposure, consisting of a single alcohol dose, mimics the “binge” drinking that is commonly observed among women who abuse alcohol during pregnancy (Anderson et al, 2014). We chose this timing of alcohol administration (PD 4-9) because, in terms of brain development, the first two weeks of rodent life correspond to the third trimester of human gestation (Dobbing and Sands, 1979; Goodlett and Johnson, 1999).…”
Section: Lack Of Nnos Function Exacerbates Alcohol’s Neuroteratogenicmentioning
confidence: 87%
“…This pattern of alcohol exposure, consisting of a single alcohol dose, mimics the “binge” drinking that is commonly observed among women who abuse alcohol during pregnancy (Anderson et al, 2014). We chose this timing of alcohol administration (PD 4-9) because, in terms of brain development, the first two weeks of rodent life correspond to the third trimester of human gestation (Dobbing and Sands, 1979; Goodlett and Johnson, 1999).…”
Section: Lack Of Nnos Function Exacerbates Alcohol’s Neuroteratogenicmentioning
confidence: 87%
“…However, 6.4% of women in one study [69], and over 33% in another [70], did not reduce their alcohol consumption during pregnancy. The effects of alcohol consumption during pregnancy can range in severity depending on the timing of exposure, with the first trimester being most sensitive to alcohol-related birth outcomes [71].…”
Section: Alcoholmentioning
confidence: 99%
“…Ethanol is teratogenic and the current UK government recommendations are for complete abstinence from alcohol consumption during pregnancy 4. Despite this advice, some women drink heavily before they realise they are pregnant, and others continue to drink through their pregnancy 5. Prenatal alcohol exposure (PAE) may lead to miscarriage, premature birth and increased perinatal morbidity and mortality 6 7…”
Section: Introductionmentioning
confidence: 99%