Risks of organic UV filters: a review of environmental and human health concern studies

Huang, Yanran; Law, Japhet Cheuk-Fung; Lam, Tsz-Ki; Leung, Kelvin Sze-Yin

doi:10.1016/j.scitotenv.2020.142486

Cited by 127 publications

(66 citation statements)

References 133 publications

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“…Phototoxic and photoallergic responses associated with traditional UV filters have been reported, 55 as well as long-term photoaging and cell damage effects. 56 The use of biocompatible and eco-friendly ingredients completely devoid of toxic effects, such as lignin, can solve this problem, leading to safer formulations, with improved SPF values and eliminating dangerous booster additives such as microplastics.…”

Section: Discussionmentioning

confidence: 99%

Green and Scalable Preparation of Colloidal Suspension of Lignin Nanoparticles and Its Application in Eco-friendly Sunscreen Formulations

et al. 2021

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Lignin nanoparticles (LNPs) are applied in several industrial applications. The nanoprecipitation of LNPs is fast and inexpensive but currently still limited to the use of hazardous organic solvents, making it difficult to apply them on a large scale. Here, we report a scalable nanoprecipitation procedure for the preparation of colloidal lignin nanoparticles (cLNPs) by the use of the green solvents dimethylisosorbide and isopropylidene glycerol. Irrespective of the experimental conditions, cLNPs showed higher UV absorbing properties and radical scavenging activity than parent LNPs and raw lignin. cLNPs were successively used in the preparation of eco-friendly sunscreen formulations (SPF 15, 30, and 50+, as evaluated by the COLIPA assay), which showed high UV-shielding activity even in the absence of synthetic boosters (microplastics) and physical filters (TiO 2 and ZnO). Biological assays on human HaCaT keratinocytes and human skin equivalents demonstrated the absence of cytotoxicity and genotoxicity, associated with an optimal protection of the skin from UV-A damage.

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Section: Discussionmentioning

confidence: 99%

Green and Scalable Preparation of Colloidal Suspension of Lignin Nanoparticles and Its Application in Eco-friendly Sunscreen Formulations

et al. 2021

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“…Indeed, filters might cause photo-allergies, phototoxic reactions, and skin irritations. Moreover, the high refractive index of inorganic filters decreases the aesthetic value of sunscreens due to the unnatural white color acquired by the skin after application [179,180]. To solve these drawbacks, inorganic filters are frequently used in a micro-or even nano-sized form, but this latter form might cause the penetration of the UV filter into the skin, causing skin allergies or irritation [181,182].…”

Section: Skin Protection-sunscreen (Uv Protection)mentioning

confidence: 99%

The Use of Calcium Phosphates in Cosmetics, State of the Art and Future Perspectives

2021

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Calcium phosphates (CaPs) belong to a class of biomimetic materials widely employed for medical applications thanks to their excellent properties, such as biodegradability, biocompatibility and osteoinductivity. The recent trend in the cosmetics field of substituting potentially hazardous materials with natural, safe, and sustainable ingredients for the health of consumers and for the environment, as well as the progress in the materials science of academics and chemical industries, has opened new perspectives in the use of CaPs in this field. While several reviews have been focused on the applications of CaP-based materials in medicine, this is the first attempt to catalogue the properties and use of CaPs in cosmetics. In this review a brief introduction on the chemical and physical characteristics of the main CaP phases is given, followed by an up-to-date report of their use in cosmetics through a large literature survey of research papers and patents. The application of CaPs as agents in oral care, skin care, hair care, and odor control has been selected and extensively discussed, highlighting the correlation between the chemical, physical and toxicological properties of the materials with their final applications. Finally, perspectives on the main challenges that should be addressed by the scientific community and cosmetics companies to widen the application of CaPs in cosmetics are given.

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“…Risks for human health are also associated to UV filters [16] as a consequence of phototoxic and photoallergic responses and, in the long term, photoaging and cell damage [17]. The absorbance spectrum of OCFs changes during the UV exposure time as a consequence of structural transformation and degradation processes [18].…”

Section: Introduction 1drawbacks Of Current Antioxidant and Uv Shielmentioning

confidence: 99%

Nano-Structured Lignin as Green Antioxidant and UV Shielding Ingredient for Sunscreen Applications

et al. 2021

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Green, biocompatible, and biodegradable antioxidants represent a milestone in cosmetic and cosmeceutical applications. Lignin is the most abundant polyphenol in nature, recovered as a low-cost waste from the pulp and paper industry and biorefinery. This polymer is characterized by beneficial physical and chemical properties which are improved at the nanoscale level due to the emergence of antioxidant and UV shielding activities. Here we review the use of lignin nanoparticles in cosmetic and cosmeceutical applications, focusing on sunscreen and antiaging formulations. Advances in the technology for the preparation of lignin nanoparticles are described highlighting structure activity relationships.

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Risks of organic UV filters: a review of environmental and human health concern studies

Cited by 127 publications

References 133 publications

Green and Scalable Preparation of Colloidal Suspension of Lignin Nanoparticles and Its Application in Eco-friendly Sunscreen Formulations

Green and Scalable Preparation of Colloidal Suspension of Lignin Nanoparticles and Its Application in Eco-friendly Sunscreen Formulations

The Use of Calcium Phosphates in Cosmetics, State of the Art and Future Perspectives

Nano-Structured Lignin as Green Antioxidant and UV Shielding Ingredient for Sunscreen Applications

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