Risks of Keratitis and Patterns of Use With Disposable Contact Lenses

A Case of a Pseudomonas Corneal Ulcer in an Occasional Use Daily Disposable Contact Lens Wearer

“…5,6 Factors related to the lens itself are implicated, and as many as 75% of some lenses show edge defects that can result in epithelial trauma. 7 Daily disposable lenses eliminate some of these factors, notably compliance with care regimens.…”

Bilateral Methicillin-Resistant Staphylococcus aureus Keratitis in a Medical Resident Following an Uneventful Bilateral Photorefractive Keratectomy

“…As with all contact lens wearers, bandage contact lens wearers after PRK should be cautioned regarding the risk of contact lens manipulation and the increased risk of infectious keratitis with poor contact lens hygiene. 19 Patients should be informed of the risk factors and warning signs of infectious keratitis and should be informed to seek medical attention immediately should they develop signs or symptoms of infectious keratitis.…”

Fighting microbial infections: A lesson from amphibian skin-derived esculentin-1 peptides

“…Despite the host's robust immune response, it is not sufficient to defeat the damage that this bacterium produces, nor the formation of corneal ulcers leading to severe vision dysfunction within 2-3 days, depending on the virulence of the bacterial strains [99,102]. The risk for bacterial keratitis is higher in contact lens wearers, particularly for overnight use of disposable lenses and extended wear modalities [1,82,94,101], because of lens-induced compromise of innate defences including reduced epithelial turnover and impaired ability to produce various antimicrobial proteins, including AMPs [31,83,99]. In addition, contact lens wear induces hypoxia and decreased production of the tear film [3], which contribute to creating a hostile environment where P. aeruginosa can easily grow [109].…”