Risks of anticoagulation in patients with chronic kidney disease and atrial fibrillation: More than just bleeding?

Risks associated with discontinuation of oral anticoagulation in newly diagnosed patients with atrial fibrillation: Results from the GARFIELD‐AF Registry

“…Notably, patients who discontinued also more frequently had concomitant renal dysfunction, which itself increases the rate of major bleeding in response to OACs 11,27,28 . Also paroxysmal AF was associated with higher discontinuation rates 29 .…”

“…Notably, patients who discontinued also more frequently had concomitant renal dysfunction, which itself increases the rate of major bleeding in response to OACs. 11,27,28 Also paroxysmal AF was associated with higher discontinuation rates. 29 In contrast, lower discontinuation was observed in patients with a higher thrombotic risk and those with a higher motivation to take OACs such as those with a prior stroke/TIA, permanent AF, a history of acute coronary F I G U R E 3 Adjusted hazard ratios for discontinuation with 95% CIs after atrial fibrillation (AF) diagnosis between patients who did and did not discontinue anticoagulation.…”

Atrial fibrillation in Middle Eastern Arabs and South Asians: Summary of published articles in the Arabian Gulf

“…[3637] Furthermore, most of the available literature describe AF in cohorts of patients with CKD showing high prevalence and incidence and associated higher morbidity and mortality. [3839404142] Yet, the clinical characteristics and outcome of patients who are hospitalized with AF and coexistent CKD have rarely been reported.…”