Risks associated with perioperative anaemia and perioperative blood transfusion in patients undergoing neurosurgical operation

Abstract

Objective: To investigate the prevalence of preoperative anaemia and the risks associated with perioperative anaemia and blood transfusion in patients who underwent neurological surgery. Background: Perioperative anaemia has an important impact on neurosurgery patients. The prevalence and risks of perioperative anaemia and blood transfusion in Chinese patients are still unknown. Methods: Logistic regression was used to predict adverse outcomes of red blood cell (RBC) transfusion and different levels of anaemia. Anaemia and transfusion were compared as independent variables by using a 1:1 match on propensity score. Results: The prevalence of preoperative anaemia in neurosurgical patients was 20.05%; 10.33% patients received RBC transfusion. Perioperative RBC and plasma transfusion rates (P < .001) and average hospital costs (P = .0365) were higher in preoperative moderate-to-severe anaemia patients than in no anaemia patients. Perioperative RBC transfusion patients had longer hospital length of stay (LOS) (P < .001) and higher average hospital costs (P < .001) than no-transfusion patients. The rates of return to the operating room (OR) within 30 days and intensive care unit stay did not demonstrate any significant difference in anaemia and transfusion cohorts, respectively. Conclusion: The status of preoperative anaemia in Chinese neurosurgical patients is associated with increased transfusion rates and hospital costs. Perioperative RBC transfusion is associated with increased length and cost of hospitalisation.

Post-operative anemia in children undergoing elective neurosurgery: An analysis of incidence, risk factors, and outcomes

“…A previous study in children undergoing cardiac surgeries documented an incidence of post-operative anemia of 27.7% among 119 patients. [ 4 ] Considering a 95% confidence level and a 5% margin of error, a minimum sample size of 87 was deemed necessary. As we also planned to explore an association between post-operative anemia and 11 potential risk factors, we inflated the sample size to 220 considering about 20 patients for each predictor variable.…”

“…[ 2 , 3 ] Both anemia and transfusion result in increased length of stay in the intensive care unit (ICU) and the hospital, increased rate of a second surgery, and increased hospital costs. [ 4 , 5 ]…”