Healthcare, religion, governance, politics, and economics have historically caused many of the world’s most significant conflicts, and they continue to do so because these issues are often the most fundamental in the structure of a society. To gain a military advantage, parties to armed conflicts have polluted water, burned crops, cut down forests, poisoned soils, and killed animals over the years. A variety of context factors, particularly socioeconomic conditions, governance, and political factors, interact and play a key role in translating climate change into conflict risks. Unrest all over the world risks putting more than half of the countries into a crisis of health, economy, and social safety, which remains the most constant threat to human civilization. The security and safety of healthcare facilities, workers, and supply lines remain of paramount concern, along with access to health services, technology, and innovation. This seminal work correlates the effects of infection pandemics, conflict, healthcare, and climate issues on the world economy. It interconnects them with victims and future public health for sustainable security in the world ecosystem. Healthcare issues, when focused on the highest platform, could compel global leaders to forego conflicts and work together.