2007
DOI: 10.1001/archinte.167.4.335
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Risk of Tuberculosis From Exposure to Tobacco Smoke

Abstract: Background: There is no consensus whether tobacco smoking increases risk of tuberculosis (TB) infection, disease, or mortality. Whether this is so has substantial implications for tobacco and TB control policies.Objective: To quantify the relationship between active tobacco smoking and TB infection, pulmonary disease, and mortality using meta-analytic methods.

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Cited by 487 publications
(383 citation statements)
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“…Although why smoking should increase the risk of MDR-TB among TB patients remains unclear, it seems possible that patients who smoke are likely to make other poor decisions with regard to their health, including being non-adherent to TB treatment. 32 Patients with a history of imprisonment were also found to have a significantly increased risk of MDR-TB, as reported in three previous studies. 26,33,34 Finally, self-reported disability that was severe enough to prevent work was also positively associated with MDR-TB.…”
Section: Discussionsupporting
confidence: 72%
“…Although why smoking should increase the risk of MDR-TB among TB patients remains unclear, it seems possible that patients who smoke are likely to make other poor decisions with regard to their health, including being non-adherent to TB treatment. 32 Patients with a history of imprisonment were also found to have a significantly increased risk of MDR-TB, as reported in three previous studies. 26,33,34 Finally, self-reported disability that was severe enough to prevent work was also positively associated with MDR-TB.…”
Section: Discussionsupporting
confidence: 72%
“…In terms of population groups, the coloured population had the highest risk for dual substance use, as has been reported in previous studies performed in SA. [34,35] Furthermore, congruent with previous findings, [1][2][3][4] TB retreatment patient status and non-adherence to anti-TB medication were associated with conjoint alcohol and tobacco use. However, unlike in other studies, [7,8,[10][11][12][13][14][15][16][17] there was no association between mental problems, PTSD, poor quality of life and alcohol and tobacco use.…”
Section: Discussionsupporting
confidence: 86%
“…[1,2] Alcohol misuse also aug ments the likelihood of developing tuberculosis (TB) and has been associated with poor treatment adherence and a significantly amplified risk of relapse and death during and after TB treatment. [1,3,4] A study in China found that smoking alone or sole alcohol consumption had no relationship with TB, but smoking together with alcohol abuse was probably a risk factor for pulmonary TB. [5] There is a high degree of association between alcohol and nicotine dependence.…”
mentioning
confidence: 99%
“…15 Tuberculosis and tobacco smoking are both global public health threats. Innumerable studies have established significant associations between tobacco smoking, prevalence of TB and adverse outcomes 16,17,18 and have concluded that smoking roughly doubles the risk of tuberculous infection, active TB disease and death. 19 The present study has found the prevalence of tobacco smoking among the TB patients to be 33.3 % (95 % CI= 24.76% to 41.84%).…”
Section: Discussion:-mentioning
confidence: 99%