2010
DOI: 10.1007/s00246-010-9680-2
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Risk of Nephropathy After Consumption of Nonionic Contrast Media by Children Undergoing Cardiac Angiography: A Prospective Study

Abstract: Despite increasing reports on nonionic contrast media-induced nephropathy (CIN) in hospitalized adult patients during cardiac procedures, the studies in pediatrics are limited, with even less focus on possible predisposing factors and preventive measures for patients undergoing cardiac angiography. This prospective study determined the incidence of CIN for two nonionic contrast media (CM), iopromide and iohexol, among 80 patients younger than 18 years and compared the rates for this complication in relation to… Show more

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Cited by 25 publications
(22 citation statements)
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“…A recent pediatric study assessing the risk of nephropathy after consumption of nonionic contrast media in children undergoing cardiac angiography found an incidence of CIN of 11.25 % for iopromide and 7.5 % for iohexol; however, none of them required dialysis. In fact, CIN as a complication of non-ionic contrast media is not rare in pediatric patients whereas renal impairment and dialysis dependency are rare [4].…”
Section: Discussionmentioning
confidence: 99%
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“…A recent pediatric study assessing the risk of nephropathy after consumption of nonionic contrast media in children undergoing cardiac angiography found an incidence of CIN of 11.25 % for iopromide and 7.5 % for iohexol; however, none of them required dialysis. In fact, CIN as a complication of non-ionic contrast media is not rare in pediatric patients whereas renal impairment and dialysis dependency are rare [4].…”
Section: Discussionmentioning
confidence: 99%
“…Although more angiographic studies and interventional catheterization are being conducted in pediatric patients, reports of severe delayed contrast reactions associated with these procedures are still limited in children [2][3][4]. Considering that delayed contrast reactions can occur anywhere from 3 h to 7 days [5] following the administration of contrast and patients are generally discharged from the radiology department within 30 min of contrast administration, it is a concern that patients experiencing delayed reactions after iodinated contrast administration may have their conditions unrecognized or neglected.…”
Section: Introductionmentioning
confidence: 99%
“…Despite the fact that there are no comprehensive studies done on CIN in large pediatric patient groups, it is known that CIN is the third most widespread reason for acute renal cases developing in hospitals, with 12% of contrast media use in all acute renal failure cases, as well (3,6,12). Furthermore, CIN is known to have ranked third in causes of mortality in postrenal failure acquired in hospitals (5).…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, CIN is known to have ranked third in causes of mortality in postrenal failure acquired in hospitals (5). However, today pediatric angiography patients can be discharged within 24-48 h, with no CIN-induced mortality or morbidity being expected or reported (12). In the studies reporting postprocedural serum creatinine follow-ups in pediatric angiography patients, the patient groups were monitored for from 48 h to 2 weeks (9,12,(17)(18)(19)(20).…”
Section: Discussionmentioning
confidence: 99%
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