Risk of adverse outcomes in offspring with RT-PCR confirmed prenatal Zika virus exposure: an individual participant data meta-analysis of 13 cohorts in the Zika Brazilian Cohorts Consortium

Ximenes, Ricardo Arraes de Alencar; Miranda-Filho, Demócrito de Barros; Brickley, Elizabeth B.; Araújo, Thália Velho Barreto de; Montarroyos, Ulísses Ramos; Abtibol-Bernardino, Marília Rosa; Mussi-Pinhata, Marisa Márcia; Duarte, Geraldo; Coutinho, Conrado Milani; Negrini, Silvia Fabiana Biason de Moura; Alecrim, Maria das Graças Costa; Peixoto, Lucíola de Fátima Albuquerque de Almeida; Moreira, Maria Elisabeth Lopes; Zin, Andréa; Júnior, José Paulo Pereira; Nielsen‐Saines, Karin; Martelli, Celina Maria Turchi; Rodrigues, Laura C.; Souza, Wayner Vieira de; Ventura, Liana O.; Oliveira, Consuelo Silva de; Matos, Haroldo de; Serra, E; Gomes, Luna Thais Souza; Nogueira, Maurício Lacerda; Estofolete, Cássia Fernanda; Vaz-Oliani, Denise Cristina Mós; Passos, Saulo Duarte; Moron, Antônio Fernandes; Rodrigues, Maria Manoela Duarte; Sarmento, Stéphanno Gomes Pereira; Turchi, Marília Dalva; Rosado, Luiza; Zara, Ana Laura de Sene Amâncio; Gomes, Maria Bárbara Franco; Schuler‐Faccini, Lavínia; Herrero-Silva, Juliana; Amorim, Melânia Maria Ramos; Melo, Adriana Oliveira; Cunha, Antônio José Lêdo Alves da; Prata‐Barbosa, Arnaldo; Amim, Joffre; Filho, Jorge Fonte de Rezende; Calcagno, Juan Ignácio; Alcântara, Luiz Carlos Júnior; Almeida, Breno Lima de; Hofer, Cristina Barroso; Machado, Elizabeth S.; Siqueira, Isadora Cristina de; Martínez-Espinosa, Flor Ernestina; Brasil, Patrícia; Leal, Mariana de Carvalho; Albuquerque, Maria de Fátima Pessoa Militão de; Malacarne, Jociele; Damasceno, Luana; Filippis, Ana María Bispo de; Santos, Cleiton Silva; Duarte, Alan Oliveira; Vasconcelos, Pedro F. C.; Machado, Mariana Borges; Bertozzi, Ana Paula Antunes Pascalicchio; Fajardo, Thamirys Cosmo Gillo; Bárbaro, Adriana Aparecida Tiraboschi; Assef, Ligia Conceição Marçal; Pimentel, Clarice; Abreu, Thalita; Tavares, Jousilene de Sales; Melo, Fabiana de Oliveira; Lima, Talita de Toledo; Brasil, Maria das Graças Nunes; Terças-Trettel, Cláudia Pereira; França, Giovanny Vinícius de Araújo; Bôtto-Menezes, Camila; Benzecry, Silvana Gomes; Robaina, Jaqueline Rodrigues; Oliveira, Mariana Barros Genuíno de

doi:10.1016/j.lana.2022.100395

Cited by 5 publications

(2 citation statements)

References 48 publications

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“…Patients with preeclampsia are typically misdiagnosed since the disorder does not manifest symptoms. Another research found that proteinuria cleared in middling of 32.6 days (10-90 days account postpartum), while a third found that it resolved in an average of 35.8 days (21-90 days postpartum) [23][24][25]. Similarly, we found that proteinuria resolved on average after 32.6 days (10-90 days postpartum).…”

Section: Discussionsupporting

confidence: 64%

Fundoscopic Findings in Pregnancy Related Hypertensive Disorders and Its Association with Maternal and Fetal Outcomes

Fakhir¹,

Shamsher²,

Anbreen³

et al. 2022

PJMHS

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Objectives: To determine the prevalence of retinal changes in pregnancy-related hypertensive disorders and their association with maternal and fetal outcomes. Introduction: There is a grave risk to both mother and child when hypertensive problems complicate pregnancy. However, hypertensive sort of disorders during pregnancy have been allied to poor maternal and also neonatal outcomes. This research aimed to evaluate effects of hypertensive sort of disorders of pregnancy on both mothers and their unborn children by analyzing the prevalence, causes, and treatment of these conditions. Subjects and methods: BBH Rawalpindi, Inpatient Department of Gynecology and Obstetrics conducted the case-control research during the period from January 2021 to June 2021. In all, 149 patients participated in the research. Because seven patients could not be located, 142 cases were analyzed. Mild class preeclampsia (65.0 instances), severe class preeclampsia (32.0 hot cases), and also eclampsia (one case) were the subcategories used to categorize patients further, according to research. Thirty-one women who were not hypertensive throughout pregnancy were enlisted as controls. Results: Ninety percent of cases manifested with some edema. About a quarter basically patients had proteinuria above 300.0 mg/24 hours (26.76%), nearly half had proteinuria over two g/24 hours (47.18%), and about a quarter had urine protein based excretion of 3.0-5.0 g/24 hours (25.35%). Usually, incidence of specially HELLP (normally hemolysis, increased liver based special enzymes, and also squat platelet tot up) set of symptoms was 2.80%, raised bilirubin levels were seen in 47%, illustration symptoms occurred in 6.4%, vaginal based hemorrhage occurred in 11.30%, in addition to 42.2% of cases involved the central nervous system. It was shown that eclampsia was the cause of mortality in 2.8% of all maternal deaths. 16.9 percent of births were stillbirths, while 4.23 percent of newborns died. Conclusion: Compared to pregnant women with normal blood pressure, those who suffer from hypertensive disorders of pregnancy have a higher risk of having a baby born with complications. Our research did find a declining trend, although it was less than those seen in other studies; this may be because more of our study's births occurred in hospitals. Keywords: Neonatal outcome, maternal outcome, acute renal failure, and the HELLP syndrome

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Section: Discussionsupporting

confidence: 64%

Fundoscopic Findings in Pregnancy Related Hypertensive Disorders and Its Association with Maternal and Fetal Outcomes

Fakhir¹,

Shamsher²,

Anbreen³

et al. 2022

PJMHS

View full text Add to dashboard Cite

show abstract

“…Among the contributions of the ZBC Consortium is the recently published article: "Risk of adverse outcomes in offspring with RT-PCR confirmed prenatal Zika virus exposure: an individual participant data metaanalysis of 13 cohorts in the Zika Brazilian Cohorts Consortium." 15 Next, we will highlight some of its points.…”

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confidence: 99%

Still on the Brazilian Response to the Microcephaly Epidemic: A Meta-analysis of 1,548 Pregnant Women from 13 Cohorts to Evaluate the Risk of Adverse Outcomes

Ximenes

Filho

Martínez-Espinosa

et al. 2023

Rev Bras Ginecol Obstet

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Impact of perinatal COVID on fetal and neonatal brain and neurodevelopmental outcomes

Brum

Vain

2023

Seminars in Fetal and Neonatal Medicine

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Risk of adverse outcomes in offspring with RT-PCR confirmed prenatal Zika virus exposure: an individual participant data meta-analysis of 13 cohorts in the Zika Brazilian Cohorts Consortium

Cited by 5 publications

References 48 publications

Fundoscopic Findings in Pregnancy Related Hypertensive Disorders and Its Association with Maternal and Fetal Outcomes

Fundoscopic Findings in Pregnancy Related Hypertensive Disorders and Its Association with Maternal and Fetal Outcomes

Still on the Brazilian Response to the Microcephaly Epidemic: A Meta-analysis of 1,548 Pregnant Women from 13 Cohorts to Evaluate the Risk of Adverse Outcomes

Impact of perinatal COVID on fetal and neonatal brain and neurodevelopmental outcomes

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