Risk group assessment of oral precancer attached to X-ray lung-screening examinations

Abstract

The mortality rate of oral tumours in Hungary, as in some other countries, is increasing. In order to assess risk groups for oral cancer and precancer, oral examinations were carried out as part of the X-ray screenings for lung cancer in the 3rd district of Budapest, Hungary. There were 5,034 adults who participated voluntarily in these investigations. After completing a questionnaire with 23 questions, a short oral examination was performed. Males comprised 57.7% of the group, and the age-distribution among men and women was similar. Oral precancerous lesions were found in 3.7% of the whole group, in 3.3% of those with leukoplakia, and in 0.4% of those with oral lichen planus. The prevalence of leukoplakia in men was 5.8%, and in women 1.5%, with significantly higher prevalences in men and women over 40. Among the examined persons there were 31% who were smokers, and 6% reported that they were regular consumers of alcohol. Fifty-four percent of those examined reported that they did not visit the dentist regularly. Oral complaints came mostly from those with lichen planus. The described model, where the oral screening examinations are done in conjunction with other examinations, in a so-called multiphasic screening system, seems to be a worthwhile approach for early diagnosis of oral cancer and precancer.

An appraisal of oral cancer and pre‐cancer screening programmes in Europe: a systematic review

“…A total of 16 OC/pre‐cancer screening studies conducted in Europe over a span of three decades were retrieved from our searches . The first of the screening programmes was conducted in 1973–1974 in Sweden (published in 1987 following a re‐evaluation) and was the largest reported so far.…”

“…Dombi et al. conducted a multiphasic screening programme for those who were willing to accept oral examinations whilst attending a lung‐screening station in the 3rd District of Budapest. Screening examinations were performed by general dental practitioners on 1 day per week over an undefined time period.…”

Prevalence of oral mucosal lesions in alcohol misusers in south London

“…In the current study, all of the leukoplakia lesions recorded were in males and smokers. Axéll (14), in Sweden, found leukoplakia in 3.6% of cases; Reichart and Kohn (23), in Berlin, found that 0.9% showed oral leukoplakia and 0.1% smoker's palate; Banoczy's group (24) from Hungary reported 3.3% with oral leukoplakia. Field et al.…”

Tobacco carcinogen mediated up‐regulation of AP‐1 dependent pro‐angiogenic cytokines in head and neck carcinogenesis

“…A growing body of evidence indicates approximately 15% of the world's malignancies are associated with chronic inflammation [39, 40]. In head and neck carcinogenesis, chronic inflammation is an accompanying feature of dysplastic lesions and at least 75% of leukoplakia lesions are associated with smoking [41–44].…”