Risk Factors of Thyroid Dysfunction in Patients With Type 2 Diabetes Mellitus

Ogbonna, S U; Ezeani, Ignatius

doi:10.3389/fendo.2019.00440

“…Subclinical hypothyroidism or hypothyroidism was reported to be the most common form of TD in several studies [6][7][8][9]. In this study, a relatively high prevalence of TD was found, among which low T3 syndrome constituted the majority.…”

Section: Discussionsupporting

confidence: 50%

Thyroid dysfunction and risk factors in patients with newly diagnosed type 2 diabetes: A cross-sectional study

Li

¹

,

Yi

²

,

Deng

³

et al. 2019

Preprint

0

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Background : Diabetes mellitus (DM) and thyroid dysfunction (TD) are two closely associated disorders. The coexistence of TD could adversely influence metabolic control and even increase the long-term mortality in patients with DM. The objective of the present study was to investigate the prevalence and risk factors of TD in patients with type 2 DM (T2DM). Methods : This is an observational cross-sectional study. A total of 340 patients with newly diagnosed T2DM who were admitted to ward of endocrinology department were included for analysis. Thyroid function was examined and its relationship with demographic, metabolic and diabetes-related parameters were evaluated Results : The prevalence of TD was 21.2% in the total population. The low T3 syndrome was the most frequent TD, in 14.7% of patients. Low FT3 level was associated with diabetic complications including presence of diabetic ketosis (DK) or diabetic ketoacidosis (DKA) (r = -0.388, P ≤ 0.001) and microalbuminuria (r = -0.302, P ≤ 0.001). Metabolic and demographic factors, including age, glycemic control and insulin resistance also correlated with levels of thyroid hormones. DK or DKA (OR = 6.161, P ≤ 0.001) and microalbuminuria (OR = 3.950, P = 0.002) were risk factors of low T3 syndrome. Conclusion : TD is not rarely seen in patients with newly diagnosed T2DM. Diabetic complications and diabetes-related metabolic and demographic factors are related to the presence of TD.

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“…Subclinical hypothyroidism or hypothyroidism was reported to be the most common form of thyroid dysfunction in several studies [6][7][8][9]. In this study, a relatively high prevalence of thyroid dysfunction was found, among which low T3 syndrome constituted the majority.…”

Section: Discussionsupporting

confidence: 48%

Thyroid dysfunction and risk factors in patients with newly diagnosed type 2 diabetes: A cross-sectional study

Li

¹

,

Yi

²

,

Deng

³

et al. 2019

Preprint

0

View full text Add to dashboard Cite

Background : Diabetes mellitus (DM) and thyroid dysfunction (TD) are two closely associated disorders. The coexistence of TD could adversely influence metabolic control and even increase the long-term mortality in patients with DM. The objective of the present study was to investigate the prevalence and risk factors of TD in patients with type 2 DM (T2DM). Methods : This is an observational cross-sectional study. A total of 340 patients with newly diagnosed T2DM who were admitted to ward of endocrinology department were included for analysis. Thyroid function was examined and its relationship with demographic, metabolic and diabetes-related parameters were evaluated Results : The prevalence of TD was 21.2% in the total population. The low T3 syndrome was the most frequent TD, in 14.7% of patients. Low FT3 level was associated with diabetic complications including presence of diabetic ketosis (DK) or diabetic ketoacidosis (DKA) (r = -0.388, P ≤ 0.001) and microalbuminuria (r = -0.302, P ≤ 0.001). Metabolic and demographic factors, including age, glycemic control and insulin resistance also correlated with levels of thyroid hormones. DK or DKA (OR = 6.161, P ≤ 0.001) and microalbuminuria (OR = 3.950, P = 0.002) were risk factors of low T3 syndrome. Conclusion : TD is not rarely seen in patients with newly diagnosed T2DM. Diabetic complications and diabetes-related metabolic and demographic factors are related to the presence of TD.

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“…[13] patient with type II diabetes problem are also at a risk of thyroid dysfunction. [14,15] although the risk is not as great as that for a Type I diabetic. [11] This is due to Type I diabetes being an autoimmune disease.…”

Section: Introductionmentioning

confidence: 97%

“…Different blood groups associated with DM and Thyroid disorderTypes of thyroid disorder accompanies with Diabetes Mellitus are illustrated infigure 6, which showed that hypothyroidism were more common in patients with DM by about 56% against 44% of hyperthyroidism. This case could be explained by the overproduction of thyroid hormones induced by the metabolism of sugar in human body [15]. types of thyroid disorders in DM patients…”

mentioning

confidence: 99%

Thyroid disorders among patients with type II Diabetes Mellitus

Salih¹

2019

KJAR

0

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Recently hospitals are full of patient suffering from several chronic diseases. Two of these diseases are Diabetes Mellitus (DM) and Thyroid diseases. DM is a chronic disease characterized by irregular abnormal elevation of blood glucose level. It is classified in to several types depending on the situation; the major types are type I and type II. Thyroid disease is an endocrine disease which characterized by over production or decrease in production of thyroid hormones by thyroid glands. The main function of thyroid hormones is the regulation of body metabolism. Both of diseases are endocrine disease. These diseases currently the major hurdle among patient and become the great challenge in front of government capability to fight the problem. These data were collected between the last months of 2017 to the 15 th of April 2018 from overall 300 patients. All the information has been collected from Diabetic and Endocrine Center, Shorsh Hospital and Medical DAIK Group in Sulaiman city. In total of 300 patients, Twenty five percent 25% of patients have both diabetes and thyroid disease. Fifty nine percent 59% of patients only have diabetes without any sign of thyroid problem, and finally only Sixteen percent 16% were have thyroid problem again without any evidence of having diabetes signs. This studyshowed that from the collection of (300) patients, seventy five (75) patients have both diabetes mellitus and thyroid diorders, these are more predominance in overage 40 years of mostly females, illiterate and housewife that mostly were insulaimani city.

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Risk Factors of Thyroid Dysfunction in Patients With Type 2 Diabetes Mellitus

Cited by 44 publications

References 49 publications

Thyroid dysfunction and risk factors in patients with newly diagnosed type 2 diabetes: A cross-sectional study

Thyroid dysfunction and risk factors in patients with newly diagnosed type 2 diabetes: A cross-sectional study

Thyroid dysfunction and risk factors in patients with newly diagnosed type 2 diabetes: A cross-sectional study

Thyroid disorders among patients with type II Diabetes Mellitus

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