Risk factors of subclinical atherosclerosis in obesity and overweight

Gabriela, Alexescu Teodora; Negrean, Vasile; Olimpia, Pfingstgraf Iulia; Claudia, Lencu Codruta; Dan, Toganel Razvan; Para, Ioana; Popovici, Ionela; Cheregi, Cornel

doi:10.5455/jpma.12075

Cited by 2 publications

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“…Sitting in front of the TV and computer while consuming calorie-rich fast food and sugary drinks, in the long run create an imbalance between the intake and consumption of energy in the body. The result of this imbalance is excess body weight (15)(16)(17)(18).…”

Section: Risk Factorsmentioning

confidence: 99%

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Obesity and atherosclerosis in children

Mesihović-Dinarević

2024

Medicinski Glasnik

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<p>Atherosclerosis, one of the leading causes of death in developed countries is characterized by lumen reduction of blood vessels due to local thickening of internal blood vessels caused by plaque/atheroma. It begins in childhood, goes for a long time without manifesting symptoms, increasing with age it begins to seriously threaten health. The most important risk factors for the development of atherosclerotic disease are: hyperlipidemia, hypertension, smoking, diabetes, high fibrinogen, excessive weight, increased level of homocysteine, physical inactivity, heredity and immune response in some diseases. The primary intention of prevention is to preclude the occurrence of risk factors for atherosclerosis, and the secondary is to prevent the development or aggravation of the illness along with the reduction or control of existing risks. There is an increasing number of studies that show that children are overweight, which in adolescence is certainly a risk factor for the onset of many chronic diseases, namely: cardiovascular, type 2 diabetes, orthopedic, and psychological diseases. The obesity epidemic is one of the most serious health problems of today affecting individuals of all ages. Atherosclerosis demands action with the aim of early detection and treatment as well as the reduction of development of risk factors for coronary artery diseases. Finding the most effective preventive measures for obesity in each country requires precise epidemiological data on the number of obese children and youth, as well as on their eating and activity habits.</p>

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Section: Risk Factorsmentioning

confidence: 99%

“…The aetiology of obesity is complex (genetic, environmental, economic factors) (8). Early childhood is a crucial period for obesity prevention (16). Children adopt eating habits from the environment in which they grow up.…”

Section: Risk Factorsmentioning

confidence: 99%

Obesity and atherosclerosis in children

Mesihović-Dinarević

2024

Medicinski Glasnik

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Histological and Microscopic Analysis of Fats in Heart, Liver Tissue, and Blood Parameters in Experimental Mice

Basheer

Malik

Awan

et al. 2023

Genes

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The intake of various types and amounts of dietary fats influences metabolic and cardiovascular health. Hence, this study evaluated the impact of routinely consumed Pakistani dietary fats on their cardiometabolic impact. For this, we made four groups of mice, each comprising 5 animals: (1) C-ND: Control mice on a normal diet, (2) HFD-DG: High-fat diet mice on a normal diet plus 10% (w/w) desi ghee, (3) HFD-O: Mice on normal diet plus 10% (w/w) plant oil (4) HFD-BG: Mice on normal diet plus 10% (w/w) banaspati ghee. Mice were fed for 16 weeks, and blood, liver, and heart samples were collected for biochemical, histological, and electron microscopic analysis. The physical factors indicated that mice fed on HFD gained more body weight than the C-ND group. Blood parameters do not show significant differences, but overall, the glucose and cholesterol concentrations were raised in the mice fed with a fat-rich diet, with the highest concentrations in the HFD-BG group. The mice fed with HFD-BG and HFD-O had more lipid droplets in the liver, compared to HFD-DG and C-ND.

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Risk factors of subclinical atherosclerosis in obesity and overweight

Cited by 2 publications

References 0 publications

Obesity and atherosclerosis in children

Obesity and atherosclerosis in children

Histological and Microscopic Analysis of Fats in Heart, Liver Tissue, and Blood Parameters in Experimental Mice

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