Risk factors of recurrent erysipelas in adult Chinese patients: a prospective cohort study

Li, Ang; Wang, Ni; Ge, Lingzhi; Xin, Hongyan; Li, Weihua

doi:10.1186/s12879-020-05710-3

Cited by 9 publications

(5 citation statements)

References 17 publications

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“…Nevertheless, Cannon et al 6 also investigated almost 30% outpatients and only included lower limb erysipelas. In agreement with previous studies, [7][8][9] we found that obesity and diabetes mellitus are strong predictors for erysipelas recurrence. Moreover, high NLR was an independent predictor for erysipelas recurrence, indicating that systemic inflammatory response mechanisms play a role in this context.…”

supporting

confidence: 93%

Clinical characteristics and complete blood count data of 506 patients with erysipelas: Predictors for length of hospitalization and recurrence

Gambichler

Schubert

Rached

et al. 2023

Acad Dermatol Venereol

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Dear Editor, The length of hospitalization and recurrence of erysipelas are important factors with regard to health costs. 1 We aimed to investigate the utility of clinical characteristics and different systemic immune-inflammation biomarkers (SIIB) as tools for the prognostication of length of hospitalization and disease recurrence.We evaluated clinical and laboratory data of 506 hospitalized patients with erysipelas. Standard therapy consisted of intravenous G penicillin adapted to renal function parameters. In case of β-lactam allergies, intravenous clindamycin was used. On admission and after about 7 days, all patients received a complete blood count. The neutrophil/lymphocyte ratio (NLR), lymphocyte/monocyte ratio (LMR), systemic immune-inflammation index (SII) and pan-immune-inflammation value (PIV) were calculated as previously reported. 2,3 Statistics included univariable (Wilcoxon test, chi-square test, receiver operating characteristics, Spearman's correlation procedure) and multivariable (logistic regression model) testing. p < 0.05 was considered statistically significant.The median blood parameters and SIIB at baseline significantly declined after 7 days inpatient treatment, except for lymphocytes and thrombocytes which significantly increased after 7 days (Table 1). Median length of hospitalization was 8 days ranging from 1 to 31 days. Prolonged hospitalization (>8 days) was observed in 217 (42.9%) of 506 patients. In 97 (19.2%) of 506 patients, the erysipelas reoccurred. The median number of relapses was 1, ranging from 1 to 20 relapses. Univariable analysis revealed that prolonged hospitalization was significantly associated with higher LMR, NLR, SII, PIV, age and localization of erysipelas on the lower extremities (Table 2). Prolonged hospitalization was significantly associated with lower lymphocyte count and LMR. Erysipelas recurrence was significantly associated with higher NLR, SII and obesity. Lower lymphocyte and monocyte counts were also significantly associated with relapse. On logistic regression, we observed that CRP and age were significant and independent predictors for prolonged hospitalization, while localization on the face was associated with lower risk of prolonged hospitalization (Table 2). Higher NLR

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confidence: 93%

Clinical characteristics and complete blood count data of 506 patients with erysipelas: Predictors for length of hospitalization and recurrence

Gambichler

Schubert

Rached

et al. 2023

Acad Dermatol Venereol

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“…The main risk factors that are more likely to be associated with recurrent episodes of cellulitis are local conditions such as diseases of the skin particularly chronic edema, 11 , 13 , 16 , 17 , 31 dermatomycosis 8 , 11 , 15 , 17 and venous insufficiency. 8 , 11 , 13 , 16 , 17 , 31 Obesity was a common factor in many studies. 8 , 20 , 31 Some studies found an association with diabetes, cancer and peripheral vascular disease.…”

Section: Risk Factors For Recurrent Cellulitismentioning

confidence: 99%

“… 8 , 11 , 13 , 16 , 17 , 31 Obesity was a common factor in many studies. 8 , 20 , 31 Some studies found an association with diabetes, cancer and peripheral vascular disease. The criteria used to diagnose these conditions in the studies are not standardized but do provide an estimate of risk of recurrence.…”

Section: Risk Factors For Recurrent Cellulitismentioning

confidence: 99%

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Recurrent Cellulitis: Who is at Risk and How Effective is Antibiotic Prophylaxis?

Ong¹,

Dotel²,

Ngian³

2022

IJGM

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Recurrent cellulitis following successful treatment is common and prevention should be a major component in the management of cellulitis. Conditions that increase the risk of recurrence include chronic edema, venous disease, dermatomycosis and obesity. These risk factors should be actively managed as further episodes of cellulitis increases the risk of recurrence. The role of non-antibiotic measures is important and should be first-line in prevention. Antibiotic prophylaxis is effective, but its role is limited to non-purulent cellulitis where risk factors are appropriately managed.

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“…É causada, principalmente, por estreptococos beta-hemolíticos do grupo A (Streptococcus pyogenes), com menor frequência pelo Streptococcus dos grupos B, C, G e, mais raro, pelo Staphylococcus aureus. Essas bactérias adentram a pele através de soluções de continuidade, como pequenas fissuras, micoses, picadas de insetos e lesões preexistentes, ocorrendo principalmente nos membros inferiores 1 .…”

Section: Introductionunclassified

Erisipela Bolhosa: um relato de caso

Justino Ferreira,

De Moraes Custódio

2023

HRJ

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Introdução: a erisipela é uma infecção bacteriana aguda da derme considerada comum. Contudo, a mesma pode se manifestar em formas mais raras, associada a complicações, como a Erisipela Bolhosa. Objetivo: relatar a apresentação clínica, manejo e evolução de um paciente com diagnóstico de Erisipela Bolhosa. Método: estudo observacional e descritivo, do tipo relato de caso, acerca de um paciente com o diagnóstico de Erisipela Bolhosa, internado em um hospital público de Brasília, Distrito Federal. Relato de caso: paciente de 46 anos, obeso, com histórico de doença venosa crônica, apresentando acometimento extenso do membro inferior direito por Erisipela Bolhosa. Utilizou-se antibioticoterapia associada a tratamento tópico com coberturas de espuma com prata e sulfadiazinade prata. Discussão: o paciente deste caso possuía vários dos fatores de risco e apresentou possíveis portas de entrada para a infecção, bem como a maioria das manifestações características da doença. Apesar da lacuna na literatura relacionada ao tratamento tópico, foi possível observar boa evolução do quadro com a estratégia de tratamento empregada. Conclusão: pesquisas futuras poderiam tentar sumarizar as evidências relacionadas à erisipela e suas complicações ou aplicar a mesma estratégia de tratamento em um número maior de pacientes para confirmar sua efetividade.

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Risk factors of recurrent erysipelas in adult Chinese patients: a prospective cohort study

Cited by 9 publications

References 17 publications

Clinical characteristics and complete blood count data of 506 patients with erysipelas: Predictors for length of hospitalization and recurrence

Clinical characteristics and complete blood count data of 506 patients with erysipelas: Predictors for length of hospitalization and recurrence

Recurrent Cellulitis: Who is at Risk and How Effective is Antibiotic Prophylaxis?

Erisipela Bolhosa: um relato de caso

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