Risk Factors of Post-Stroke Epilepsy in Children; Experience from a Tertiary Center and a Brief Review of the Literature

Polat, İpek; Yış, Uluç; Ayanoğlu, Müge; Okur, Derya; Edem, Pınar; Paketçi, Cem; Bayram, Erhan; Kurul, Semra Hız

doi:10.1016/j.jstrokecerebrovasdis.2020.105438

Cited by 9 publications

(3 citation statements)

References 37 publications

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“…The most common presenting symptom among patients who had an AIS was acute focal neurological deficit, which was consistent with the literature reports 6. Seizures occurred in 17.16% cases, which was consistent with Silverman and Zelano’s7 8 reports that poststroke seizures occurred in 5%–20%, but lower than Polat et al ’s9 report (59% patients).…”

Section: Discussionsupporting

confidence: 89%

Childhood strokes in China describing clinical characteristics, risk factors and performance indicators: a case-series study

et al. 2021

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AimTo investigate clinical characteristics, risk factors (RFs), neurologic deficits and medical care provided in children who had a stroke in China.MethodsWe conducted a retrospective case-series study using the medical records of children aged 1 month to 18 years with arterial ischaemic stroke (AIS) or haemorrhagic stroke (HS) (with the entry codes I60, I61, I62, I63 (ICD-10)), who were admitted to different hospitals in Beijing, between January 2018 and December 2018. We obtained the following information from the charts: demographic characteristics, clinical presentations, RFs for paediatric stroke, laboratory examination, neuroimaging records and neurologic sequelae.ResultsWe identified 312 first admissions for stroke (172 AIS and 140 HS). The mean age at onset was 8.6±3.9 years for patients who had an AIS and 8 (5–13) years for patients who had an HS. There were more males than females in both groups (AIS: 59.88% vs 40.12%; HS: 52.14% vs 47.86%). A known aetiology was identified in 92.44% and 86.43% of patients who had an AIS and HS, respectively. The leading cause of AIS was cerebrovascular diseases including moyamoya (68.6%), while that for HS was arteriovenous malformation (51.43%). The most common initial clinical presentation was hemiplegia (86.05%) in patients who had an AIS and headache (67.86%) in patients who had an HS. The use of healthcare, including acute treatment (antithrombotic in 17.44%, anticoagulant in 5.23%) and secondary prevention (antithrombotic in 6.39%, anticoagulant in 1.16%), varied and was significantly lower among patients who had an AIS. The most common complications were epilepsy (22.09%) and pneumonia (4.65%) in patients who had an AIS and epilepsy (17.14%) and hydrocephalus (12.14%) in patients who had an HS. Neurological deficits occurred in 62.8% of patients who had an AIS and 72.86% of patients who had an HS.ConclusionCerebral arteriopathy was a major RF for both AIS and HS in children living in China. Large epidemiological studies are required to identify RFs to prevent stroke as well as appropriate interventions.

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Section: Discussionsupporting

confidence: 89%

Childhood strokes in China describing clinical characteristics, risk factors and performance indicators: a case-series study

et al. 2021

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“…One of the most common causes of epilepsy is a stroke. For example, blood circulation to the brain may be disrupted, leading to a stroke [ 1 ]. Stroke symptoms include difficulty communicating, breathing, and comprehending and facial, arm, or leg numbness or paralysis.…”

Section: Introductionmentioning

confidence: 99%

[Retracted] Clinical Characteristics and Gene Mutation Analysis of Poststroke Epilepsy

Shen

Deng

Chun-yan

et al. 2022

Contrast Media & Molecular Imaging

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Epilepsy is one of the most common brain disorders worldwide. Poststroke epilepsy (PSE) affects functional retrieval after stroke and brings considerable social values. A stroke occurs when the blood circulation to the brain fails, causing speech difficulties, memory loss, and paralysis. An electroencephalogram (EEG) is a tool that may detect anomalies in brain electrical activity, including those induced by a stroke. Using EEG data to determine the electrical action in the brains of stroke patients is an effort to measure therapy. Hence in this paper, deep learning assisted gene mutation analysis (DL-GMA) was utilized for classifying poststroke epilepsy in patients. This study suggested a model categorizing poststroke patients based on EEG signals that utilized wavelet, long short-term memory (LSTM), and convolutional neural networks (CNN). Gene mutation analysis can help determine the cause of an individual’s epilepsy, leading to an accurate diagnosis and the best probable medical management. The test outcomes show the viability of noninvasive approaches that quickly evaluate brain waves to monitor and detect daily stroke diseases. The simulation outcomes demonstrate that the proposed GL-GMA achieves a high accuracy ratio of 98.3%, a prediction ratio of 97.8%, a precision ratio of 96.5%, and a recall ratio of 95.6% and decreases the error rate 10.3% compared to other existing methods.

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“…Following pediatric AIS, the development of seizures is a concern. One study found that 59% of pediatric, post-stroke patients went on to have a seizure shortly thereafter, and a startling 41% of patients went on to develop epilepsy [17]. Due to this, seizure prophylaxis is typically started, at least in the acute setting.…”

Section: Discussionmentioning

confidence: 99%

Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies

Deskins¹,

Mamone²,

Luketich³

et al. 2022

Cureus

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Acute ischemic stroke (AIS) is a significant source of morbidity and mortality and is one of the top causes of death in the United States. Of these patients, most are elderly individuals, compared to a limited proportion of cases seen in pediatrics. AIS is classically associated with age-dependent atherosclerotic disease processes secondary to comorbidities such as diabetes and hypertension. When considering the pediatric population, stroke is far less common and often requires workup of other underlying etiologies that create a hypercoagulable state. Here we present a case of an eight-year-old male with a left middle cerebral artery (MCA) ischemic stroke in the setting of increased factor VIII activity and SARS-CoV-2 antibodies.

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Risk Factors of Post-Stroke Epilepsy in Children; Experience from a Tertiary Center and a Brief Review of the Literature

Cited by 9 publications

References 37 publications

Childhood strokes in China describing clinical characteristics, risk factors and performance indicators: a case-series study

Childhood strokes in China describing clinical characteristics, risk factors and performance indicators: a case-series study

[Retracted] Clinical Characteristics and Gene Mutation Analysis of Poststroke Epilepsy

Acute Ischemic Stroke in an Eight-Year-Old Male With Elevated Factor VIII Activity and SARS-CoV-2 Antibodies

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