Risk Factors of Pneumothorax and Bleeding

Yeow, Kee‐Min; Su, I-Hao; Pan, Kuang-Tse; Tsay, Pei-Kwei; Lui, Kar‐Wai; Cheung, Yun‐Chung; Chou, Andy Shau-Bin

doi:10.1378/chest.126.3.748

Cited by 362 publications

(158 citation statements)

References 22 publications

Supporting

Mentioning

120

Contrasting

Order By: Relevance

“…Regarding the small size of the nodules in this study which is known to be a risk factor for pneumothorax, the overall complication rate was 38% and the pneumothorax rate was 25.4%, which may be acceptable compared with the reported pneumothorax rate of more than 30% for small nodules of 2 cm or smaller in other studies [24][25][26]. Complications were more likely to be related to the PCNB procedure itself and specific complications of CBCT have not yet been reported.…”

Section: Discussionmentioning

confidence: 51%

Initial experience of percutaneous transthoracic needle biopsy of lung nodules using C-arm cone-beam CT systems

et al. 2010

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 51%

Initial experience of percutaneous transthoracic needle biopsy of lung nodules using C-arm cone-beam CT systems

et al. 2010

View full text Add to dashboard Cite

show abstract

“…Yeow et al . [21] published a large consecutive series of 660 patients who underwent cutting needle biopsies of the lung and found that the highest pneumothorax rate correlated with a lesion size <2 cm and a lesion depth of 0,1 to 2 cm. The risk factors for highest bleeding rate are lesion size <2 cm, lesion depth >2.1 cm, and lung lesions not associated with a pleural effusion.…”

Section: Discussionmentioning

confidence: 99%

Computer tomography-guided core biopsies in a county hospital in Sweden: Complication rate and diagnostic yield

et al. 2014

View full text Add to dashboard Cite

BACKGROUND:Core biopsies are valuable in obtaining sufficient tissue to ensure diagnosis of diseases in the thorax.OBJECTIVE:To evaluate the complication rate and the diagnostic yield in computer tomography (CT)-guided core biopsies performed in a county hospital in Sweden.METHODS:Medical journals, spirometry results, pathology reports and CT scans were reviewed in 463 consecutive cases, where a transthoracic core biopsy was performed between January 2005 and December 2010. Of these 380 (82%) were lung lesions, 48 (10%) were mediastinal lesions and 35 (8%) were pleural lesions.RESULTS:All patients underwent a chest X-ray 4 hours post-biopsy and pneumothorax was seen in 156/463 (34%) patients: 137 after lung biopsy and 17 after mediastinal biopsy. Chest tube insertion was required for 27 (17%) of these patients (6% of all core biopsies). Small intraparenchymal hemorrhages and hemoptysis were observed with subjective difficulty in one case. The diagnostic yield for the 463 patients was 212 (46%) cases of lung cancer, 188 (41%) benign lesions and 39 (8%) pulmonary metastases.CONCLUSIONS:A transthoracic core biopsy ensures diagnosis with a low complication rate and is suitable as an outpatient procedure. An increased risk for pneumothorax was observed when the biopsied lesion was small or when emphysema was in the path of the biopsy needle. Reduced lung function pre-biopsy or emphysema in the path of the biopsy needle increased the need for chest tube treatment of pneumothorax. A CT-guided core biopsy is safe and applicable in a county hospital.

show abstract

“…Other risk factors for pneumothorax include the presence of small lesions/nodules, long needle path (>4 cm), and repeated pleural puncture (10). The rate of pneumothorax for CT-guided lung biopsies averages from20 to 25% with 2–5% requiring treatment such as chest tube placement (11–14). The pneumothorax rate for CT-guided biopsies in our program was within this range of expected incidence.…”

Section: Discussionmentioning

confidence: 99%

Tumor Acquisition for Biomarker Research in Lung Cancer

Stevenson¹,

Christensen²,

Shoemaker³

et al. 2014

Cancer Investigation

View full text Add to dashboard Cite

The biopsy collection data from two lung cancer trials that required fresh tumor samples be obtained for microarray analysis were reviewed. In the trial for advanced disease, microarray data were obtained on 50 patient samples, giving an overall success rate of 60.2%. The majority of the specimens were obtained through CT-guided lung biopsies (N=30). In the trial for early-stage patients, 28 tissue specimens were collected from excess tumor after surgical resection with a success rate of 85.7%. This tissue procurement program documents the feasibility in obtaining fresh tumor specimens prospectively that could be used for molecular testing.

show abstract

Risk Factors of Pneumothorax and Bleeding

Cited by 362 publications

References 22 publications

Initial experience of percutaneous transthoracic needle biopsy of lung nodules using C-arm cone-beam CT systems

Initial experience of percutaneous transthoracic needle biopsy of lung nodules using C-arm cone-beam CT systems

Computer tomography-guided core biopsies in a county hospital in Sweden: Complication rate and diagnostic yield

Tumor Acquisition for Biomarker Research in Lung Cancer

Contact Info

Product

Resources

About