Risk factors of early spontaneous abortions among Japanese: a matched case-control study

Baba, Sachiko; Noda, Hiroyuki; Nakayama, Masahiro; Waguri, Masako; Mitsuda, Nobuaki; Iso, Hiroyasu

doi:10.1093/humrep/deq343

Cited by 36 publications

(38 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…pollutants) and miscarriage risk (Green et al 2009;Sunil 2011). Lastly, substance abuse (cigarette, alcohol, drugs) has been associated with increased miscarriage risk (Baba et al 2011;Venners et al 2004;Oats and Abraham 1995;Lerner 2003) While close to 70 percent of all miscarriages happen before the 12 th week of pregnancy, the timing of miscarriage varies (see Figure 1.A). Cytogenetic analysis studies have shown that chromosomal abnormalities can cause spontaneous miscarriage at a range of gestational ages accounting for over 50 percent of all pregnancies lost before week 12 (with the peak prevalence at weeks 10-11) and over 35 percent of all pregnancies lost after week 12 (Kajii et al 1980;Eiben et al 1990;Hogge et al 2003;Philipp et al 2003 Our identification strategy relies on the assumption that miscarriages are correlated with the friend's childbearing status and uncorrelated with unobservable characteristics of the woman.…”

Section: Miscarriage As a Natural Experimentsmentioning

confidence: 99%

Learning from Teen Childbearing Experiences of Close Friends: Evidence using Miscarriages as a Natural Experiment

Yakusheva

Fletcher

2015

Review of Economics and Statistics

View full text Add to dashboard Cite

We examine peer effects in teen childbearing among close friends, using miscarriages as a natural experiment. We use 775 women from the core sample of Add Health who had a friend with a teen pregnancy. We find a sizable negative treatment effect -a close friend's teen birth is associated with a 6 percentage point reduction in the likelihood of own teen pregnancy and childbearing. There is evidence that this effect operates through a learning mechanism by changing beliefs regarding early childbearing. Effects of teen pregnancy prevention policies may be partially offset by reductions in the opportunities for social learning.

show abstract

Section: Miscarriage As a Natural Experimentsmentioning

confidence: 99%

Learning from Teen Childbearing Experiences of Close Friends: Evidence using Miscarriages as a Natural Experiment

Yakusheva

Fletcher

2015

Review of Economics and Statistics

View full text Add to dashboard Cite

show abstract

“…Such socioeconomic factors played an influential part in the health and life expectancies of the pregnancy and impact on pregnant outcomes, for people in low SES are more likely to show risky behavioral patterns and enjoy limited access to health services [10, 11]. A great number of, even as many as abundant, studies have well established the association among SES, onset of non-communicable diseases and cancer [12, 13].…”

Section: Introductionmentioning

confidence: 99%

Factors associated with spontaneous abortion: a cross-sectional study of Chinese populations

Zheng

et al. 2017

Reprod Health

View full text Add to dashboard Cite

BackgroundSpontaneous abortion (SA) is one of the prevalent negative reproductive outcomes among women around the world, which is a great challenge faced by maternal health promotion. The present study is aimed to explore the association between SA and socioeconomic status (SES) and provides reference for policy makers to improve strategies on maternal health promotion.MethodsA cross-sectional analysis was conducted with baseline data from a large-scale population-based cohort study of 0.5 million people from 10 geographically diverse areas of China recruited from 2004 to 2008. The study collected data from 84,531 women aged 35–45 years old in the baseline survey of China Kadoorie Biobank. Participants were interviewed using a standardized questionnaire, and information on demographic-socioeconomic as well as reproductive health status was collected. Odds ratios (OR) with 95% CI, estimated by a multistep logistic regression, were used to approximate the associations between SA occurrence and characteristics of SES. A stratification analysis was also applied to find out how SES influenced women’s reproductive health outcomes differently between rural and urban areas. The model was adjusted for age at study date, tea consumption, alcohol consumption, cigarette smoking, and number of induced abortion.ResultsThe risk of SA in rural was 1.68 times greater than in urban (AOR = 1.68, 95%CI: 1.54–1.84). Women with high income had a decreased risk of SA when compared with that of women with low income (AOR = 0.90, 95%CI: 0.84–0.97). Compared with women in low educational attainment, women in higher educational attainment had a lower prevalence of SA (AOR = 0.90, 95%CI: 0.82–0.98). The risk of SA only reduced in factory worker (AOR = 0.59, 95%CI: 0.53–0.66) and professional worker (AOR = 0.75, 95%CI: 0.66–0.84) compared with agriculture and related workers. After stratifying by rural/urban, the association between income and SA in urban (AOR = 0.88, 95%CI: 0.78–0.99) was stronger than that in rural (AOR = 0.92, 95%CI: 0.84–1.00). Association between education and SA was found in urban (AOR = 0.66, 95%CI: 0.55–0.78) but not in rural (AOR = 1.05, 95%CI: 0.34–1.17), and there was no difference on how occupation impacted SA among women between the two subgroups.ConclusionsGenerally women with lower SES status had a higher risk of SA. Lower income and educational attainment were inversely associated with the risk of SA. Women with agricultural and related work had a significantly higher prevalence of SA. Interventions could be targeted more on women with low SES to increase both health profits as well as economic gains for health programs.Electronic supplementary materialThe online version of this article (doi:10.1186/s12978-017-0297-2) contains supplementary material, which is available to authorized users.

show abstract

“…Nearly 80% of miscarriages occur in the first trimester and the risk factors for the progression of a normal pregnancy to a complete miscarriage in the first trimester are properly well established [2]. Common risk factors include genetic anomalies, maternal age (35 years or older), high prepregnancy body mass index, history of previous miscarriage or ectopic pregnancy, and cardiovascular diseases [3].…”

Section: Introductionmentioning

confidence: 99%

Association between platelet indices and first trimester miscarriage

Akin

Kasap²,

Yuvacı³

et al. 2016

Blood Coagulation &Amp; Fibrinolysis

View full text Add to dashboard Cite

We aimed to measure the effect of several potential risk factors on first trimester miscarriage. A total of 169 cases were included in the present study. Patients were selected from women who had first trimester miscarriage (n = 78) and controls were selected from the women who had given birth at term (> 37 weeks of gestation) to healthy infants (n = 91). Compared with the control group, in the miscarriage group gestational age (8.9 ± 2.8 weeks and 8.1 ± 2.2 weeks, respectively, P = 0.032), mean platelet volume (MPV) (8.8 ± 1 and 9.5 ± 1.1 fl, respectively, P < 0.001), plateletcrit (0.209 ± 0.03% and 0.241 ± 0.05%, respectively, P < 0.001), and platelet/lymphocyte ratio (128 ± 37 and 145 ± 60, respectively, P = 0.027) were significantly higher. Multivariate analysis showed that first trimester miscarriage development ratio was 1.909 times higher when MPV value was over 9.1 fl (P < 0.001); 9.147 times higher when plateletcrit value was over 0.219% (P = 0.022). Receiver operating characteristic analysis was performed to determine diagnostic MPV and plateletcrit values for first trimester miscarriage. MPV value greater than 9.1 fl determined miscarriage with 60% sensitivity and 65% specificity, while plateletcrit value greater than 0.219% determined miscarriage with 64.5% sensitivity and 64.7% specificity. MPV and plateletcrit values were strongly associated with first trimester miscarriage. Platelet indices can be used for prediction of fetal loss.

show abstract

Risk factors of early spontaneous abortions among Japanese: a matched case-control study

Abstract: Our finding suggests that for Japanese women, smoking and working may be important public health issue targets for the prevention of early spontaneous abortions.

Cited by 36 publications

References 26 publications

Learning from Teen Childbearing Experiences of Close Friends: Evidence using Miscarriages as a Natural Experiment

Learning from Teen Childbearing Experiences of Close Friends: Evidence using Miscarriages as a Natural Experiment

Factors associated with spontaneous abortion: a cross-sectional study of Chinese populations

Association between platelet indices and first trimester miscarriage

Contact Info

Product

Resources

About