Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis

Abstract

Electroencephalogram (EEG) recordings provide a valuable, noninvasive method for measuring human brain activity. This protocol modi es our general protocol for EEG recording (Farrens et al., 2019) for use during the COVID-19 pandemic. It was created with the help of numerous experts, and it speci es a clear set of steps for interacting with research participants, using personal protective equipment (PPE), and disinfecting equipment, all with the goal of reducing the COVID-19 risks for both laboratory personnel and participants. It focuses on the use of EEG in relatively simple research studies of adults who can easily understand and follow instructions, yet can be readily adapted for studies using other types of EEG experiments or other participant populations.

Smoking Is Associated With COVID-19 Progression: A Meta-analysis

“…[8][9][10][11][12][13][14][15][16][18][19][20][21][22][23][24][25][26] Only one 17 of the studies reported unadjusted and adjusted ORs using multivariate analysis; after adjusting for confounding by age, maximum temperature at admission, respiratory failure, severe illness, albumin, creatinine, procalcitonin, and C-reactive protein level, the effect of smoking on disease severity increased (unadjusted: OR 12.19, 95% CI 1.76-84.31, p = .011; adjusted: OR 14.29, 95% CI 1.58-25.0, p = .018). Three peer-reviewed meta-analysis papers 6,34,35 on association between smoking and COVID-19 were also based on unadjusted ORs, but with fewer studies included.…”

Systematic Review and Meta-Analysis of Sex-Specific COVID-19 Clinical Outcomes

“…Furthermore, a nationwide COVID-19 surveillance study conducted in Italy indicated that male mortality rates related to COVID-19 were disproportionately higher than that of female patients with a ratio as much as 4 to 1 (Remuzzi and Remuzzi, 2020). Other systematic reviews performed to characterize clinical features or risk factors for COVID-19, have also identified the sex-specific disparities in disease severity and mortality Zheng et al, 2020).…”

Managing hypertension during the COVID-19 pandemic

“…Early data from China and the United States suggest that hypertension appears to be the most prevalent comorbidity among patients admitted with COVID-19 being present in at least 30-49% of them [4,5]. Hypertensive patients who develop COVID-19 are more likely to be admitted to hospital than normotensive individuals [6].…”