Risk factors of cough in non-small cell lung cancer patients after video-assisted thoracoscopic surgery

Lin, Rongjia; Che, Guowei

doi:10.21037/jtd.2018.08.54

Cited by 36 publications

(46 citation statements)

References 47 publications

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“…Approximately 25-50% of patients have been reported to experience cough after lung cancer surgery. [3][4][5] Postoperative cough is known to be related to mediastinal lymph node resection, history of chronic obstructive pulmonary disease (COPD), loss of lung volume, and bronchial scarring. [6][7][8] Postoperative cough may last for an extended period after surgery and can reduce patient quality of life (QOL).…”

Section: Introductionmentioning

confidence: 99%

Analysis of factors related to chronic cough after lung cancer surgery

Zhu

Zhou

Wu³

et al. 2019

Thoracic Cancer

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Background In this study, we investigated the relationship between chronic cough and clinicopathological features in postoperative patients with non‐small cell lung cancer (NSCLC) and evaluated the effectiveness of acupuncture therapy for the treatment of postoperative chronic cough in patients with NSCLC. Methods We retrospectively evaluated 171 patients with NSCLC who received lobectomy at our center between September 2017 and February 2018. The Mandarin Chinese version of the Leicester Cough Questionnaire (LCQ‐MC) was used to evaluate the degree of cough in patients. Postoperative cough was assessed by a visual analog scale (VAS). Results The total LCQ‐MC score for the whole group was 19.79 ± 0.53 before surgery and 18.40 ± 0.70 after surgery (p < 0.001). Logistic regression analysis showed that right lung cancer, difficult airway, acute cough and history of COPD were independent predictors of chronic cough. Of the 68 patients diagnosed with chronic cough, 41 received acupuncture therapy (acupuncture therapy group), and 27 received no acupuncture therapy (no therapy group). No significant difference was found between the two groups in terms of their LCQ‐MC scores at eight weeks after surgery (p = 0.756). However, the acupuncture therapy group had a significantly higher LCQ‐MC score than the no therapy group at 10 weeks after surgery (p = 0.002). Conclusions Right lung cancer, difficult airway, acute cough, and history of COPD are independent predictors of chronic cough after surgery. For patients with chronic cough, acupuncture therapy can shorten the recovery time and improve quality of life after surgery.

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Section: Introductionmentioning

confidence: 99%

Analysis of factors related to chronic cough after lung cancer surgery

Zhu

Zhou

Wu³

et al. 2019

Thoracic Cancer

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“…The LCQ is a reliable method and has been used in many clinical trials as an outcome measure [13,21,25] . Lin et al [22] described that in patients receiving video-assisted thoracoscopic surgery for lung cancer, the mean postoperative total score was 16.35, which was signi cantly lower than the mean follow-up score after 1 month, but the authors did not provide the data of preoperative levels. In our previous study, we found that thyroidectomy was signi cantly associated with a decreased LCQ score compared to baseline scores, but the study did not report when the LCQ scores returned to preoperative levels.…”

Section: Discussionmentioning

confidence: 99%

“…Risk factors for postoperative cough following surgical procedures have been occasionally analyzed. Lin et al [22] demonstrated that a long duration of anesthesia time, female sex, subcarinal node resection and lower paratracheal node resection were independent risk factors related to cough in non-small-cell lung cancer patients after surgery. Chen et al [23] reported a correlation between pulmonary surgery and postoperative cough, and the probability of postoperative cough was higher in more invasive patients.…”

Section: Discussionmentioning

confidence: 99%

Incidence and risk factor for short term postoperative cough after thyroidectomy

Dai

Lou

2020

Preprint

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Background : The prevalence of and potential risk factors for postoperative cough after thyroidectomy remain unknown. The current study aimed to analyze postoperative cough in patients undergoing thyroidectomy using a prospective analysis. Methods : Adult patients undergoing primary thyroidectomy were prospectively enrolled. Data regarding age, sex, BMI, pathology and surgical procedure were collected and analyzed. All patients were asked to complete the Leicester Cough Questionnaire (LCQ) preoperatively and at 2 weeks and 4 weeks postoperatively. Results : There were 1264 patients enrolled in total. Eleven patients with vocal cord paralysis were excluded. In patients with benign disease, postoperative cough occurred in 61 patients, with an prevalence rate of 17. 0% compared to an prevalence rate of 33.1% in patients with malignant disease; the difference was significant. For benign patients, the factors of smoking and operation time were independently related to the occurrence of postoperative cough. For malignant patients, the factors of smoking, operation time, operation extent, and the number of positive nodes at level 6 were independently related to the occurrence of postoperative cough. There was no significant difference regarding the LCQ score in patients with benign or malignant disease at the preoperative and the postoperative 4-week time periods. Patients with malignant disease had a significantly lower LCQ score than patients with benign disease at the postoperative 2-week time point (p=0.004). Conclusions : Patients undergoing thyroid cancer surgery had a higher prevalence of postoperative cough and were also associated with a decreased cough-related quality of life. The factors of smoking and operation time were the most important predictors for postoperative cough after thyroidectomy.

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“…Risk factors for postoperative cough following surgical procedures have been occasionally analyzed. Lin et al [12] demonstrated that a long duration of anesthesia time, female sex, subcarinal node resection and lower paratracheal node resection were independent risk factors for postoperative cough in patients with non-small cell lung cancer. The correlation between lung surgery and postoperative cough was reported by Chen et al [24].…”

Section: Discussionmentioning

confidence: 99%

“…The LCQ is a reliable method and has been used in many clinical trials as an outcome measure [15,23,26]. Lin et al [12] described that in patients receiving video-assisted thoracoscopic surgery for lung cancer, the mean postoperative total score was 16.35, which was signi cantly lower than the mean follow-up score after 1 month, but the authors did not provide the data of preoperative levels. In our previous study, we found that thyroidectomy was signi cantly associated with a decreased LCQ score compared to baseline scores, but the study did not report when the LCQ scores returned to preoperative levels.…”

Section: Discussionmentioning

confidence: 99%

Incidence and risk factor for short term postoperative cough after thyroidectomy

Dai

Lou

2020

Preprint

View full text Add to dashboard Cite

BackgroundThe prevalence of and potential risk factors for postoperative cough after thyroidectomy remain unknown. The current study aimed to analyze postoperative cough in patients undergoing thyroidectomy using a prospective analysis.MethodsAdult patients undergoing primary thyroidectomy were prospectively enrolled. Data regarding age, sex, BMI, pathology and surgical procedure were collected and analyzed. All patients were asked to complete the Leicester Cough Questionnaire (LCQ) preoperatively and at 2 weeks and 4 weeks postoperatively.ResultsThere were 1264 patients enrolled in total. Eleven patients with vocal cord paralysis were excluded. In patients with benign disease, postoperative cough occurred in 61 patients, with an prevalence rate of 17. 0% compared to an prevalence rate of 33.1% in patients with malignant disease; the difference was significant. For benign patients, the factors of smoking and operation time were independently related to the occurrence of postoperative cough. For malignant patients, the factors of smoking, operation time, operation extent, and the number of positive nodes at level 6 were independently related to the occurrence of postoperative cough. There was no significant difference regarding the LCQ score in patients with benign or malignant disease at the preoperative and the postoperative 4-week time periods. Patients with malignant disease had a significantly lower LCQ score than patients with benign disease at the postoperative 2-week time point (p=0.004).ConclusionsPatients undergoing thyroid cancer surgery had a higher prevalence of postoperative cough and were also associated with a decreased cough-related quality of life. The factors of smoking and operation time were the most important predictors for postoperative cough after thyroidectomy.

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Risk factors of cough in non-small cell lung cancer patients after video-assisted thoracoscopic surgery

Cited by 36 publications

References 47 publications

Analysis of factors related to chronic cough after lung cancer surgery

Analysis of factors related to chronic cough after lung cancer surgery

Incidence and risk factor for short term postoperative cough after thyroidectomy

Incidence and risk factor for short term postoperative cough after thyroidectomy

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