Risk factors of bone mineral density deficit and low-energy fractures in primary osteoporosis in men

Родионова, С. С.; Хакимов, У Р

doi:10.17816/vto201825122-29

Cited by 3 publications

(1 citation statement)

References 10 publications

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“…While examining 231 men, the researchers found that smoking, alcohol consumption, age, mutations in homozygous form of gene rs2412298 and presence of low-energy (fragility) fractures in the first kinship relatives increased the low-energy (fragility) vertebral fracture, and less frequently, the proximal femur fracture risk [25]. The authors claim that the low BMD values associated with genetic disorders may testify to the fact that osteoporosis in the older males has a "pediatric" origin, while age, along with the smoking and alcohol addiction, is the vertebral fracture risk factor.…”

Section: Fig1 Distribution Of the Examined Males According To Their Bone Mineral Density (Normal Osteopenia Osteoporosis)mentioning

confidence: 99%

Age-related changes in bone tissue in men

Musiienko

Zaverukha

2021

PJS

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The purpose of the study was to establish age-related changes of male bone tissue. Materials and methods. The study was conducted by the Department of Clinical Physiology and Pathology of the Musculoskeletal System of the State Institution “D.F. Chebotarev Institute of Gerontology by the National Academy of Medical Sciences of Ukraine”. It involved 342 healthy men aged 20 to 89 years without osteoporosis and osteoporotic fractures or any pathology with a confirmed impact on bone tissue, as well as any somatic pathology in the sub- and decompensation. The following methods of examination were used: questionnaire, anthropometric measurements, clinical and instrumental examination. Bone mineral density (BMD) was measured by the dual-energy X-ray absorptiometry machine “Prodigy, GEНС Lunar” at the level of the entire skeleton, lumbar spine (L1-L4), proximal femur and femoral neck, distal and ultra-distal forearm bones. Results. We have detected a significant 14.8 % decrease of BMD at the level of femoral neck in the group of men aged 60–69 years, by 20 % in the group of men aged 70–79 years, and by 24.1 % in the group of men aged 80–89 years compared to the men aged 20–29 years; at the same time, at the lumbar spine there was registered a decrease of this parameter by 1.6 % in men aged 60–69 years, by 1.9 % in men of 70–79 years and by 0.8 % in men of 80–89 years, respectively. Among the examined practically healthy men, the bone tissue remained at the normal level relative to age in 67.8 %; osteopenia was detected in 27.8 %, and osteoporosis in 4.4 %. Conclusions. An age-associated BMD reduction was registered at various skeletal sites in the practically healthy men without any clinically significant factors affecting bone tissue metabolism. The most pronounced BMD loss was observed at the level of femoral neck. At the same time, 4.4 % of examined had osteoporosis without any clinical signs.

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Section: Fig1 Distribution Of the Examined Males According To Their Bone Mineral Density (Normal Osteopenia Osteoporosis)mentioning

confidence: 99%

Age-related changes in bone tissue in men

Musiienko

Zaverukha

2021

PJS

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Results of Densitometric Assessment in the Case of Mandibular Jawbone Atrophy on the Left

Ошурко

2022

VPBM

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Densitometric assessment in the justification of rehabilitation of patients with atrophy of the bone tissue of the mandible, on the right side

Ошурко

2022

Rep. of Morph.

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Densitometric methods for determining bone density are increasingly becoming fundamental in research and a priority in clinical applications in medical practice. Rehabilitation of patients with bone atrophy becomes impossible without assessing its density and, at the same time, is an important component in the diagnosis and planning of reconstructive surgery, in particular, prognosticity in the use of osteoplastic materials or osteointegration of dental implants. The aim of the study was to conduct a densitometric assessment to substantiate the rehabilitation of patients with atrophy of the mandible, on the right side, in the age groups of 25 to 75 years. Computed tomography digital scan scans obtained using the Vatech PaX-I 3D Green extra-oral radiography system and processed by the standardized X-ray diagnostic software Ez3D-I Original ver.5.1.9.0. Using the tools of the horizontal option panel, in particular the keys of the interface “profile”, the density of bone tissue with interpretation in conventional units of grayness (CUG) in the projection of 4.6, 4.7 teeth was investigated. To obtain qualitatively homogeneous values, we used nonparametric methods of statistical analysis of comparison of age groups – using the multidimensional Kruskal-Wallis test as an alternative intergroup analysis of variance, for simultaneous comparison of three samples. It is proved that during the statistical analysis of bone density using the Mann-Whitney U test in the studied areas of the mandible on the right, the total average number of M experimental (E) groups compared to the average number of the control group (C), high reliability in vertical (VP) measurements and confirmed p<0.05. Thus, it is proved that the early loss of the masticatory group of teeth, in the first group of studies (25-45 years), leads to high rates, with increasing bone density in the direction of distalization of the final defect of the dentition. Conversely, the lack of functional action on bone tissue in the second (46-60 years) and third (61-75 years) groups of the study, leads to a decrease in its density, and, consequently, to the devastation of the trabecular layer, which contributes to the progression of atrophic processes.

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Risk factors of bone mineral density deficit and low-energy fractures in primary osteoporosis in men

Cited by 3 publications

References 10 publications

Age-related changes in bone tissue in men

Age-related changes in bone tissue in men

Results of Densitometric Assessment in the Case of Mandibular Jawbone Atrophy on the Left

Densitometric assessment in the justification of rehabilitation of patients with atrophy of the bone tissue of the mandible, on the right side

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