Risk factors from HBV infection among blood donors: A systematic review

Abstract

Objective: To perform a systematic review of the scientific literature to identify risk factors associated with hepatitis B viruses (HBV) infection among blood donors. Methods: The literature search was carried out on PubMed and Scopus databases using the keywords "risk factors" "HBV infection" and "blood donors". No date or language restrictions were applied to the search. This literature review was completed in March 2014. The selection process and the reporting of the review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement. The Newcastle Ottawa scale was using to evaluate the quality of each single primary study. Results: Out of 172 records resulted in the search, 5 papers were included in the final analysis because they are within acceptance criteria. Two of the selected studies were cross-sectional and three of them were case-control studies. Significant association resulted with some demographic and behavioral risk factors, such as marital status, dental treatment/procedure history, no stable relationship or multiple partners and family history of HBV infection. Conclusions: The systematic review performed encourages to conduct further research among blood donors in order to fully understand risk factors among donors in more extensive thus to provide valuable information about surveillance.

Hepatitis B in Egypt: A cross‐sectional analysis of prevalence and risk factors for active infection from a nationwide survey

“…8 Little is known about HBV prevalence among specific risk groups in Egypt (eg, intravenous drug users), in contrast to HCV. 9 And while risk factors for HBV infection are well-characterised in the literature in general, [10][11][12] data specific to the Egyptian context are few and multiple modes of transmission have been noted. 13 Previous work in Egypt has shown strong associations between distal risk factors such as literacy and HBV risk, 14 but age-related effects have not been investigated, although a cohort effect in HCV prevalence has been demonstrated possibly resulting from parenteral antischistosomal therapy (PAT) campaigns in the 1950s and 1960s.…”

A Study of Hepatitis B Virus Associated Risk Factors in Patients Attending Hepatitis Unit in Duhok City, Iraq

“…No study has been conducted in the region to determine HBV-associated risk factors. Although HBV can be transmitted via direct contact with blood, transfusion of blood and blood products, intravenous injections, and unprotected sex (9), the prevalence of risk factors differs from a society to another according to the norms and traditions of that society (10)(11)(12). Therefore, for the establishment of public health plan to combat HBV infection, deter- mining the risk factor of infection transmissions in a society is of great importance.…”

Prevalence of hepatitis B virus infections among blood donors in Federal Capital Territory, Abuja, Nigeria

“…Although, the incidence of transfusion transmitted hepatitis B has been gradually controlled within the intervening period, the available records show that HBV remains yet the viral infection with the greatest risk of transmission through blood transfusion especially in developing countries. An obviously high variability in the prevalence of HBV is seen across the countries, with higher incidence and prevalence observed in developing nations such as 1.6%-7.7% in Brazil, 19.6% in Egypt and 2-10% across India (6). In Nigeria, the pooled prevalence of HBV is reported to be about 13.6% (7).…”