Risk Factors for the Recurrence of Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis

Li, Shichang; Wang, Zijing; Liu, Yan; Cao, Jie; Zheng, Hongwei; Jing, Yuanyuan; Han, Lin; Ma, Xin; Xia, Ruiming; Yu, Lisheng

doi:10.1177/0145561320943362

Cited by 36 publications

(44 citation statements)

References 112 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We demonstrated the higher recurrence rate of BPPV among female patients and those with low BMD (osteopenia/osteoporosis), which were consistent with the previous results [10][11][12]23].…”

Section: Discussionsupporting

confidence: 92%

“…However, including our study, the other studies showed a similar recurrence rate of posttraumatic BPPV compared with idiopathic one [22]. Moreover, type of the involved semicircular canals did not affect the recurrence rate of BPPV in our study, as replicated by other studies [10].…”

Section: Discussionsupporting

confidence: 86%

“…There have been studies with conflicting results regarding the recurrence of BPPV, since multiple factors including clinical settings, and even genetic backgrounds might have influence on the occurrence of BPPV [10][11][12]17]. For example, previous studies suggested that the patients with BPPV had higher frequency of vascular comorbidities (i.e., hypertension, diabetes mellitus, and hyperlipidemia), and these might also increase the risk of the recurrence in BPPV [11,17,18].…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, several studies reported the association of BPPV with inner ear diseases including vestibular neuritis, Menière's disease as well as vascular risk factors (e.g., hypertension, diabetes mellitus) [7]. Previous studies on the recurrence and long-term prognosis of BPPV conducted by domestic and international investigators have shown that similar factors that increase the risk of BPPV might be associated with the recurrence of BPPV as well [8][9][10][11][12]. However, the results were considerably inconsistent among studies and still need to be elucidated.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Clinical Characteristics of Recurrent Benign Paroxysmal Positional Vertigo: A Retrospective Cohort Study

Kim¹,

Cho²,

Lee³

et al. 2021

Res Vestib Sci

View full text Add to dashboard Cite

Objectives: Benign paroxysmal positional vertigo (BPPV) is a potentially recurrent disease even after successful canalith repositioning maneuvers. However, the exact recurrence rate or any clinical factors affecting the recurrence of BPPV still need to be elucidated. Methods: We recruited patients diagnosed as BPPV in a tertiary hospital for 3 years. We retrospectively reviewed the clinical information of the patients including baseline demographics, comorbidities and predisposing factors through the electronic medical records. We performed a telephone survey or direct interview 3 to 6 years later from the initial diagnosis of BPPV was made. To determine the factors associated with the recurrence, we divided study population into two subgroups; 'recurrence group' vs. 'recurrence-free group.' Then, intergroup comparative analyses were performed. Results: Among 397 patients who were originally eligible for the study, we performed a telephone survey or direct interview in 289 patients (72.8%) to determine the recurrence of BPPV. The overall recurrence rate was 29.4% (85 of 289). Baseline demographics except female gender (p=0.014) were not different between subgroups. Neither clinical characteristics nor vascular comorbidities were associated with the recurrence. However, patients with low bone mineral density (BMD; T-score below -1, osteopenia/osteoporosis) showed significantly higher recurrence than those with normal BMD (40.6% vs. 0%, p=0.009). Conclusions: Female gender and low BMD (T-score below -1) were associated with the recurrence of BPPV in this study. Further researches in various clinical settings with larger sample size are warranted to identify the factors affecting the relapse of BPPV.

show abstract

“…We demonstrated the higher recurrence rate of BPPV among female patients and those with low BMD (osteopenia/osteoporosis), which were consistent with the previous results [10][11][12]23].…”

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical Characteristics of Recurrent Benign Paroxysmal Positional Vertigo: A Retrospective Cohort Study

Kim¹,

Cho²,

Lee³

et al. 2021

Res Vestib Sci

View full text Add to dashboard Cite

show abstract

“…Prevention: BPPV is known to recur frequently. Reported rates of recurrence in BPPV vary considerably, ranging from 16 to 50% [52,53], and some reports correlated an increased rate of recurrence with aging [54,55]. In patients with recurrent BPPV, vitamin D deficiency was shown to be a relevant cofactor [56].…”

Section: Benign Paroxysmal Positional Vertigo (Bppv)mentioning

confidence: 99%

Current Insights into Treating Vertigo in Older Adults

Casani¹,

Gufoni²,

Capobianco³

2021

Drugs Aging

View full text Add to dashboard Cite

The number of older people has been increasing over recent decades in Western populations. Dizziness, imbalance, and vertigo constitute some of the most common complaints in older patients, and risk of falling is the most frequent and worrying consequence. It has been reported that 15-20% of the adult population experiences these debilitating symptoms. Among the diseases that may be associated with vertigo, the three classes of otological, central, and functional (psychological) dizziness may be distinguished. Overall, vestibular disorders account for 48% of vertiginous complaints in the older population. The main focus of this article is to review the forms of pharmacotherapy for vertigo, especially with regard to older patients, who may be treated simultaneously with other drugs for different comorbidities. Interactions with other drugs should be considered in the choice of a particular course of treatment. Moreover, overuse of pharmacotherapy for the management of vertigo in the elderly may prevent the development of the central compensatory mechanism that sustains both static and dynamic imbalance after a vertiginous crisis. In the majority of patients, vestibular and physical rehabilitation are strongly advised and rarely contraindicated.

show abstract

Randomized Controlled Trial Assessing Vitamin D's Role in Reducing BPPV Recurrence in Older Adults

Chua,

Huang,

Koh

et al. 2024

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

ObjectiveTo determine if the recurrence rates of BPPV in older adults were lower in the vitamin D‐treated group as compared to placebo groups.Study DesignDouble‐blinded randomized control placebo trial.SettingA single‐centre study.MethodsDouble‐blinded randomized controlled trial design with 12 months follow‐up. Vitamin D3 deplete participants were randomized into treatment (Group A) or placebo groups (Group B). Treatment group received 13 weeks of 2000 IU vitamin D3 followed by 1000 IU for the next 13 weeks. Patients who were replete were allocated to a control group (Group C) for observation and follow up. All groups had dietary interventions for vitamin D3 and calcium.ResultsResults showed an 87% reduction in recurrence rates of BPPV in the treatment group (Group A), with 0.75 fewer clinical episodes per 1 person‐year as compared to placebo (Group B). Time to first recurrence was also significantly longer in Group A. There was no statistically significant difference between Group A and C in both recurrence rates and dizziness handicap scores.ConclusionsThis clinical trial has laid the foundation to expand the investigation of vitamin D as standard of care treatment in BPPV patients in future phase IIb and III studies.SummaryA reduction in BPPV episodes in older adults has implications on fall risk, as dizziness from BPPV may cause falls. With fewer BPPV episodes and longer time to recurrence, seniors may have better postural stability and hence reduced risk of falls.Level of Evidence2.

show abstract

Risk Factors for the Recurrence of Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis

Cited by 36 publications

References 112 publications

Clinical Characteristics of Recurrent Benign Paroxysmal Positional Vertigo: A Retrospective Cohort Study

Clinical Characteristics of Recurrent Benign Paroxysmal Positional Vertigo: A Retrospective Cohort Study

Current Insights into Treating Vertigo in Older Adults

Randomized Controlled Trial Assessing Vitamin D's Role in Reducing BPPV Recurrence in Older Adults

Contact Info

Product

Resources

About