Risk factors for recurrent vulvovaginal candidiasis in women receiving maintenance antifungal therapy: Results of a prospective cohort study

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“…The fact that there is no cure even after such a prolonged treatment course, with 60-70% having a recurrent episode within two months [94,116], may lead to frustration among the patients who may not accept and/or use antifungals for the next episode. Martinez [146] reported that the frequent and/or long-term antifungal therapy may predispose to bacterial vaginosis [146], and Patel et al [52] observed that young women with bacterial vaginosis may have an increased risk of genital candidiasis [52].…”

“…Rylander et al [72] found an association between consumption of sweets and a positive culture of Candida [72]. Patel et al [52] noted that consumption of cranberry was associated with a ≥2 risk of RVVC [52]. Donders et al [77] opined that diets rich in refined sugar may increase the risk of genital candidiasis [77].…”

“…RVVC [31,52]. Vermitsky et al [100] reported an increase in percentages of non-albicans Candida with increasing age of the woman [100].…”

“…Likewise wearing of tight-fitting clothes, non-cotton underwears, panty liners and hoses have been reported to increase local genital temperature, humidity and moisture, thus increasing the risk of genital candidiasis [52,62]. Local hypersensitivity or allergic reaction triggered by feminine hygienic practices may predispose some women to colonization with Candida or symptomatic infections [63].…”

Candidíase vulvovaginal: fatores predisponentes do hospedeiro e virulência das leveduras

“…Aproximadamente 5% das mulheres com CVV desenvolvem CVVR, definida usualmente como a ocorrência de quatro ou mais episódios de CVV no período de 12 meses (40,47) . Ao contrário das mulheres que têm episódios esporádicos de CVV, aquelas com a doença recorrente não se beneficiam de uma diminuição na freqüência de episódios sintomáticos com o passar da idade (40) .…”