Risk factors for potential pulmonary embolism in the patients with deep venous thrombosis: a retrospective study

Xiao, Shiqian; Geng, Xin; Zhao, Jian‐Lan; Fu, Linlin

doi:10.1007/s00068-018-1039-z

Cited by 7 publications

(4 citation statements)

References 7 publications

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“…Finally, the thrombus develops in the deep veins of lower extremeties. Triggerred by surgical operations, drug adminstration, or patient activities, the clot falls off, travels with circulation, reaches right atrium and ventricle, blooks the main body or branches of pulmonary arteries, and ends up with PTE ( Soo Hoo, 2013 ; Xiao et al, 2018 ).…”

Section: Specific Pathogenic Mechanisms For Pulmonary Thromboembolism Associated With Deep Vein Thrombosismentioning

confidence: 99%

In situ Pulmonary Artery Thrombosis: A Previously Overlooked Disease

Cao

Geng

et al. 2021

Front. Pharmacol.

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Pulmonary thromboembolism (PTE) is the third leading cause of death in cardiovascular diseases. PTE is believed to be caused by thrombi detached from deep veins of lower extremities. The thrombi travel with systemic circulation to the lung and block pulmonary arteries, leading to sudden disruption of hemodynamics and blood gas exchange. However, this concept has recently been challenged by accumulating evidence demonstrating that de novo thrombosis may be formed in pulmonary arteries without deep venous thrombosis. On the other hand, chronic thromboembolic pulmonary hypertension (CTEPH), a subtype of pulmonary hypertension, could have different pathogenesis than traditional PTE. Therefore, this article summarized and compared the risk factors, the common and specific pathogenic mechanisms underlying PTE, in situ pulmonary artery thrombosis, and CTEPH at molecular and cellular levels, and suggested the therapeutic strategies to these diseases, aiming to facilitate understanding of pathogenesis, differential diagnosis, and precision therapeutics of the three pulmonary artery thrombotic diseases.

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Section: Specific Pathogenic Mechanisms For Pulmonary Thromboembolism Associated With Deep Vein Thrombosismentioning

confidence: 99%

In situ Pulmonary Artery Thrombosis: A Previously Overlooked Disease

Cao

Geng

et al. 2021

Front. Pharmacol.

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“…VTE may result in morbidity and mortality through pulmonary embolism (PE), postthrombotic syndrome, and symptomatic DVT [1520][1521][1522][1523][1524][1525] . Without anticoagulation, risk of VTE after orthopaedic surgery has been estimated from 40% -80% 1526,1527 . Anticoagulation protocols are designed to balance the benefits of reducing these complications with the risks of bleeding.…”

Section: Marc Carrier Alex C Spyropoulosmentioning

confidence: 99%

Recommendations from the ICM-VTE: General

2022

Journal of Bone and Joint Surgery

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“…As generally acknowledged, the aged might have less smooth vessel wall, higher blood viscosity, and relatively lower blood flow velocity [26,27]. However, few reports exhibit no statistical difference in age [28]. These contradictory findings may be due to heterogeneity, sampling error, and younger onset age for GC.…”

Section: Discussionmentioning

confidence: 99%

Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population

Song

Wang

Zhu

et al. 2021

BioMed Research International

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The aim of the present work was to investigate the risk factors for gastric cancer- (GC-) associated thrombotic diseases in a Han Chinese population. A total of 333 patients diagnosed with GC, 68 with thrombotic diseases included in the case group and the remaining 265 in the control group, were enrolled. The relevant data for the participants, including general information (gender, age, smoking, and drinking), comorbidities (diabetes, hypertension, and anemia), tumor-related data (tumor site, histology, degree of differentiation, and clinical stage), and treatment-related data (surgery, chemotherapy, hormones, transfusion, and peripherally inserted central venous catheter (PICC)), were collected. Statistically significant factors derived from univariate analyses were then subjected to multivariate logistic regression analyses. The results demonstrate a statistically significant difference in age, diabetes, hypertension, histology, surgery, chemotherapy, and PICC ( P < 0.05 ), compared with control. Age, diabetes, surgery, and PICC serve as independent risk factors for GC-associated thrombotic diseases ( P < 0.05 ). The present work demonstrates that GC-associated thrombotic diseases are significantly associated with age, diabetes, surgery, and PICC, suggesting a potential target for early detection and preventive strategy for GC patients with thrombophilia.

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Risk factors for potential pulmonary embolism in the patients with deep venous thrombosis: a retrospective study

Cited by 7 publications

References 7 publications

In situ Pulmonary Artery Thrombosis: A Previously Overlooked Disease

In situ Pulmonary Artery Thrombosis: A Previously Overlooked Disease

Recommendations from the ICM-VTE: General

Risk Factors for Gastric Cancer-Associated Thrombotic Diseases in a Han Chinese Population

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