Risk factors for post-transplant tuberculosis

John, George T.; Shankar, Viswanathan; Abraham, Ajay; Mukundan, U; Thomas, Paulose P.; Jacob, C. K.

doi:10.1046/j.1523-1755.2001.0600031148.x

Cited by 161 publications

(173 citation statements)

References 7 publications

Supporting

Mentioning

158

Contrasting

Unclassified

Order By: Relevance

“…Patients receiving MMF and those with HCV infection were found to be the vulnerable groups.Similar susceptibility and higher incidence of TB in HCV infected patients has been reported by other centres from India [24,25]. Varicella affected 19% (chickenpox in 13% and herpes zoster in 6%) of our patients and was the commonest acute viral infection.…”

Section: Discussionsupporting

confidence: 89%

Renal Transplantation - An Experience of 500 Patients

Varma¹,

Hooda²,

Sinha³

et al. 2007

Medical Journal Armed Forces India

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 89%

Renal Transplantation - An Experience of 500 Patients

Varma¹,

Hooda²,

Sinha³

et al. 2007

Medical Journal Armed Forces India

View full text Add to dashboard Cite

“…2 In most developed countries, TB mostly affects older people, recent immigrants from developing countries, members of ethnic minorities and the immunocompromised (mainly HIV). Other populations at risk for developing TB are those with diabetes mellitus, 15 those on immunosuppressive medication post organ transplantation 16 and populations receiving treatment with tumour necrosis factor alpha (TNF-␣) antagonists for rheumatoid arthritis and other autoimmune diseases. 17 HIV infection substantially increases the risk of developing TB once infected with the bacillus, and also shortens the time to development of the disease.…”

Section: Tuberculosis In the Ukmentioning

confidence: 99%

A systematic review of rapid diagnostic tests for the detection of tuberculosis infection

Dinnes¹,

Deeks²,

Kunst³

et al. 2007

Health Technol Assess

530

361

View full text Add to dashboard Cite

Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £300 per volume. Please see our website for details. Subscriptions can only be purchased for the current or forthcoming volume. Contact details are as follows: Payment methods Paying by chequeIf you pay by cheque, the cheque must be in pounds sterling, made payable to Direct Mail Works Ltd and drawn on a bank with a UK address. Paying by credit cardThe following cards are accepted by phone, fax, post or via the website ordering pages: Delta, Eurocard, Mastercard, Solo, Switch and Visa. We advise against sending credit card details in a plain email. Paying by official purchase orderYou can post or fax these, but they must be from public bodies (i.e. NHS or universities) within the UK. We cannot at present accept purchase orders from commercial companies or from outside the UK. How do I get a copy of HTA on CD?Please use the form on the HTA website (www.hta.ac.uk/htacd.htm). Or contact Direct Mail Works (see contact details above) by email, post, fax or phone. HTA on CD is currently free of charge worldwide.The website also provides information about the HTA Programme and lists the membership of the various committees. HTA NIHR Health Technology Assessment ProgrammeT he Health Technology Assessment (HTA) programme, now part of the National Institute for Health Research (NIHR), was set up in 1993. It produces high-quality research information on the costs, effectiveness and broader impact of health technologies for those who use, manage and provide care in the NHS. 'Health technologies' are broadly defined to include all interventions used to promote health, prevent and treat disease, and improve rehabilitation and long-term care, rather than settings of care. The research findings from the HTA Programme directly influence decision-making bodies such as the National Institute for Health and Clinical Excellence (NICE) and the National Screening Committee (NSC). HTA findings also help to improve the quality of clinical practice in the NHS indirectly in that they form a key component of the 'National Knowledge Service'. The HTA Programme is needs-led in that it fills gaps in the evidence needed by the NHS. There are three routes to the start of projects. First is the commissioned route. Suggestions for research are actively sought from people working in the NHS, the public and consumer groups and professional bodies such as ...

show abstract

“…Extra pulmonary symptoms are sometimes atypical such as an unusual gastro-intestinal symptomatology, skin lesions not improved by antibiotics and/or dissemination [16,31,34].…”

Section: Disscussionmentioning

confidence: 99%

Mycobacterium Tuberculosis Infection Following Kidney Transplantation

Boubaker¹,

Abderrahim²,

Abdallah³

et al. 2013

AJMSM

View full text Add to dashboard Cite

Tuberculosis (TB) is one of the major causes of morbidity and mortality worldwide. Post-transplant TB is a problem in successful long-term outcome of renal transplantation recipients. It is a life-threatening opportunistic infection that is frequently encountered, but the diagnosis is often delayed. With the emergence of newer potent immunosuppressive regimens and an increased incidence of TB in the general population, post-transplant TB among transplant recipients can be anticipated. Our objective was to describe the pattern and risk factors of TB infection, and the prognosis in our transplant recipients. This study was a retrospective review of the records of 491 renal transplant recipients in our hospital during the period from January 1986 to December 2009. The demographic data, transplant characteristics, clinical manifestations, diagnostic criteria, treatment protocol, and long-term outcome of this cohort of patients were analyzed. 16 patients (3.2%) developed posttransplant TB with a mean age of 32.5 ± 12.7 (range: 13-60) years and a mean post-transplant period of 36,6 months (range: 12,3 months -15.9 years). The forms of the diseases were pulmonary in 10 /16 (62.6%), disseminated in 3/16 (18.7%) and extrapulmonary in 3/16 (18.7%). All patients initially received 4-drug combination therapy. Because of drug interaction, an increase in the dose of calcineurium inhibitor and steroid was done in 2 cases and in steroids alones in 1 case. Graft dysfunction was observed in 7 cases (43,7%) with tissue-proof acute rejection in 3 cases and loss of the graft in 4 cases. Hepatotoxicity developed in 3 patients (18.7%) during treatment. Reccurence were observed in 4 cases after early stop of treatment. Two patients (12.5%) died. Extrapulmonary and disseminated tuberculosis were observed in third of our patients. More than 9 months of treatment may be necessary to prevent recurrence.

show abstract

Risk factors for post-transplant tuberculosis

Cited by 161 publications

References 7 publications

Renal Transplantation - An Experience of 500 Patients

Renal Transplantation - An Experience of 500 Patients

A systematic review of rapid diagnostic tests for the detection of tuberculosis infection

Mycobacterium Tuberculosis Infection Following Kidney Transplantation

Contact Info

Product

Resources

About