Risk Factors for Poor Quality of Life among Patients with Age-Related Macular Degeneration

Chatziralli, Irini; Mitropoulos, Panagiotis; Parikakis, Efstratios; Niakas, Dimitris; Labiris, Georgios

doi:10.1080/08820538.2016.1181192

Cited by 33 publications

(45 citation statements)

References 31 publications

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“…conference abstract); seven articles because of language-restrictions; and one article because they utilised the same sample source from a study that was already included. 10 Of the 22 included studies, nine used a crosssectional design, 9,10,26-32 eight compared cases with controls, 8,24,[33][34][35][36][37][38] and five studies compared the target population to normative data. 25,[39][40][41][42] Findings from the normative comparison studies were summarised by a narrative approach.…”

Section: Search Resultsmentioning

confidence: 99%

“…32 In the majority of the studies, participants had visual impairment or blindness caused by various eye conditions [8][9][10][24][25][26][27][28][30][31][32]36,39,40 . In contrast, two studies specifically included patients with glaucoma, 33,35 four studies solely focused on AMD, 29,34,37,42 and in two separate studies patients either had diabetic retinopathy (DR) 38 or Usher syndrome type 1. 41 Two studies specifically included patients who were legally blind 36,39 and one study included patients with multiple sensory impairments.…”

Section: Search Resultsmentioning

confidence: 99%

“…24 Because of the limited number of identified studies, we decided to include all abovementioned criteria of visual impairment and blindness. For case-control studies, control groups were comprised of persons without ocular disease in three studies, 34,35,37 healthy participants without chronic disability in two studies, 36,38 persons with normal (self-reported) vision in two studies, 8,24 and hospital controls without glaucoma in one study. 33 Quality assessment Table 2 shows the methodological quality of the individual studies pooled by meta-analysis in this review.…”

Section: Search Resultsmentioning

confidence: 99%

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The association between visual impairment and fatigue: a systematic review and meta‐analysis of observational studies

Schakel

Bode

Elsman

et al. 2019

Ophthalmic Physiologic Optic

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Purpose The aim was to compare fatigue levels between patients with visual impairment and controls with normal sight and to examine the association between fatigue and vision loss severity. Methods A systematic literature search was performed using databases of PubMed, Embase, PsycINFO and Cochrane to identify observational studies with outcomes related to fatigue (e.g. vitality subscale of the Short‐Form 36, Fatigue Assessment Scale). A meta‐analysis was performed using standardised mean differences (SMDs) and odds ratios (OR) to quantitatively summarise the association between visual impairment and fatigue. Sources of heterogeneity were explored by subgroup and sensitivity analyses. Study quality was assessed with the Newcastle‐Ottawa scale. Results After reviewing 4477 studies, 22 studies with a total of 40 004 participants were included, of which 18 contributed to meta‐analysis. Among these, eight were assessed as moderate quality studies and 10 as high quality studies. Pooled analysis involving 2500 patients and 8395 controls showed higher fatigue severity levels (S.M.D. = −0.36, 95% CI −0.50 to −0.22, 14 studies) among visually impaired patients compared to normally sighted controls. This effect size was small and persisted in sensitivity analyses that involved study quality, fatigue assessment tools and visual acuity data. Furthermore, pooled analysis of four studies including 2615 patients and 5438 controls showed a significant association between visual impairment and fatigue (OR = 2.61, 95% CI 1.69 to 4.04). Secondary meta‐analysis of four studies showed no significant difference in fatigue severity (S.M.D. = 0.01, 95% CI −0.37 to 0.39) between patients with moderate visual impairment and patients with severe visual impairment or blindness. Conclusions Current moderate to high quality evidence suggest that patients with visual impairment experience more severe fatigue symptoms than persons with normal sight. However, a limited number of available studies indicates that fatigue is not associated with severity of vision loss. Future studies are required to determine which factors and underlying mechanisms may explain the association between visual impairment and fatigue. Discussing fatigue at an early stage and developing intervention options for vision‐related fatigue should be considered within the field of low vision rehabilitation.

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Section: Search Resultsmentioning

confidence: 99%

Section: Search Resultsmentioning

confidence: 99%

Section: Search Resultsmentioning

confidence: 99%

See 1 more Smart Citation

The association between visual impairment and fatigue: a systematic review and meta‐analysis of observational studies

Schakel

Bode

Elsman

et al. 2019

Ophthalmic Physiologic Optic

View full text Add to dashboard Cite

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“…Loss of ability to drive may therefore represent far more than a practical inconvenience and should be approached in this light when discussed with patients or their carers. (3), cataract, glaucoma (11) and macular degeneration (11,29) samples; from dry eye syndrome out-patient and community samples (30) and population reference groups (11,29) including an older group (60 years and over) with normal eye health (31) ( Table 3).…”

Section: Safe-guarding Home and Normal Lifementioning

confidence: 99%

A qualitative exploration of the experience and quality of life of patients, and their family carers, admitted to a specialist eye hospital with microbial keratitis

Tranter

Careras-Aguas

Riddell

et al. 2019

Preprint

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Background: Microbial keratitis is a vision-threatening condition requiring intensive treatment. Understanding patients’ and carers’ experience during and after hospitalisation can inform improvements in care and outcomes. This study explored the vision-related quality of life, and the experiences of patients with microbial keratitis and their family carers when admitted to a quaternary referral eye hospital in Australia Methods: The study employed mixed methods, including qualitative interviews and a survey in hospital and a telephone interview post-discharge. A convenience sample was recruited of 33 patients with microbial keratitis who presented to hospital between March and October 2017, and 10 of their family carers. Semi-structured interviews were audiotaped, transcribed verbatim, coded and analysed using thematic analysis. Patient participants completed the National Eye Institute Visual Functioning Questionnaire – 25 (NEIVFQ-25). Results: Qualitative analyses identified two main themes: Saving sight, with subthemes of costs of saving sight, and travel and transportation; Safe-guarding home and normal life with subthemes of family, work and pastimes. A group mean NEIVFQ-25 score of 74 was similar to other ophthalmic disease groups but pain scores were higher. Conclusion: Findings provide insights into the experiences and often unspoken concerns of microbial keratitis patients and their family carers, revealing the priority and the associated costs of saving sight, and the implications for family and lifestyles. These patients reported similarly reduced vision-related quality of life but greater pain compared to other ophthalmic groups. Findings point to ways to improve their experience and potentially reduce the high rates of unplanned representations of this patient group.

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“…However, the NEIVFQ-25 has been used with other groups, allowing location of this sample in relation to clinical and community groups. Findings are available for microbial keratitis (3), cataract, glaucoma (11) and macular degeneration (11,29) samples; from dry eye syndrome out-patient and community samples (30) and population reference groups (11,29) including an older group (60 years and over) with normal eye health (31) ( Table 3).…”

Section: Safe-guarding Home and Normal Lifementioning

confidence: 99%

A qualitative exploration of the experience and quality of life of patients, and their family carers, admitted to a specialist eye hospital with microbial keratitis

Tranter

Careras-Aguas

Riddell

et al. 2019

Preprint

View full text Add to dashboard Cite

Background Microbial keratitis is a vision-threatening condition requiring intensive treatment. Understanding patients’ and carers’ experience during and after hospitalisation can inform improvements in care and outcomes. This study explored the vision-related quality of life, and the experiences of patients with microbial keratitis and their family carers when admitted to a quaternary referral eye hospital in Australia Methods The study employed mixed methods, including qualitative interviews and a survey in hospital and a telephone interview post-discharge. A convenience sample was recruited of 33 patients with microbial keratitis who presented to hospital between March and October 2017, and 10 of their family carers. Semi-structured interviews were audiotaped, transcribed verbatim, coded and analysed using thematic analysis. Patient participants completed the National Eye Institute Visual Functioning Questionnaire – 25 (NEIVFQ-25). Results Qualitative analyses identified two main themes: Saving sight, with subthemes of costs of saving sight, and travel and transportation; Safe-guarding home and normal life with subthemes of family, work and pastimes. A group mean NEIVFQ-25 score of 74 was similar to other ophthalmic disease groups but pain scores were higher. Conclusion Findings provide insights into the experiences and often unspoken concerns of microbial keratitis patients and their family carers, revealing the priority and the associated costs of saving sight, and the implications for family and lifestyles. These patients reported similarly reduced vision-related quality of life but greater pain compared to other ophthalmic groups. Findings point to ways to improve their experience and potentially reduce the high rates of unplanned representations of this patient group.

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Risk Factors for Poor Quality of Life among Patients with Age-Related Macular Degeneration

Abstract: Patients with AMD presented lower quality of life in comparison with controls. Potential risk factors should be taken into account and clinicians should thus focus on the most vulnerable subgroups.

Cited by 33 publications

References 31 publications

The association between visual impairment and fatigue: a systematic review and meta‐analysis of observational studies

The association between visual impairment and fatigue: a systematic review and meta‐analysis of observational studies

A qualitative exploration of the experience and quality of life of patients, and their family carers, admitted to a specialist eye hospital with microbial keratitis

A qualitative exploration of the experience and quality of life of patients, and their family carers, admitted to a specialist eye hospital with microbial keratitis

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