Risk factors for overweight and obesity, and changes in body mass index of Chinese adults in Shanghai

Hou, Xuhong; Wang, Jia; Bao, Yuqian; Lu, Huijuan; Jiang, Shan; Zuo, Yi; Gu, Huijie; Xiang, Kun–san

doi:10.1186/1471-2458-8-389

Cited by 74 publications

(61 citation statements)

References 35 publications

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“…The proportion of overweight participants (BMI>23) based on Asian criteria [18] in this study was 29.2%. The low average BMI and the low proportion of overweight participants are comparable to other studies in Shanghai [26] , and are representative of the general urban female population of Shanghai. Since previous studies [27][28][29][30] mainly focused on the relationship between vitamin D insufficiency and insulin resistance in obese populations, the results of our study provide evidence that abnormal vitamin D status may play a role in the pathogenesis of diabetes in a population with relatively low BMI.…”

Section: Discussionsupporting

confidence: 85%

Association of serum 25-hydroxyvitamin D with insulin resistance and β-cell function in a healthy Chinese female population

Tao

Zeng

et al. 2013

Acta Pharmacol Sin

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Aim: To assess associations of the serum level of 25-hydroxyvitamin D with insulin resistance and β-cell function in a healthy Chinese female population. Methods: This cross-sectional study included 1382 female participants free of type 2 diabetes who were recruited in Shanghai. Blood samples were collected within a winter season and the serum levels of 25-hydroxyvitamin D, fasting plasma glucose and insulin, and other biochemical parameters were determined. Insulin resistance and β-cell function were assessed using the homeostasis model assessments of insulin resistance (HOMA-IR) and β-cell function (HOMA-B), respectively. Results: Multiple linear regression analyses adjusted for age, parathyroid hormone, Ca 2+ and BMI revealed that independent inverse associations existed between the serum level of 25-hydroxyvitamin D and HOMA-IR (P<0.001) and between the serum level of 25-hydroxyvitamin D and HOMA-B (P=0.001). Conclusion: Serum vitamin D level is significantly and independently associated with insulin resistance and β-cell function in a healthy Chinese female population.

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Section: Discussionsupporting

confidence: 85%

Association of serum 25-hydroxyvitamin D with insulin resistance and β-cell function in a healthy Chinese female population

Tao

Zeng

et al. 2013

Acta Pharmacol Sin

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“…Receiver operating characteristic analysis was also used to indicate the optimal cutoffs of waist circumference and BMI to identify the individuals with VAT over 90 cm 2 . The optimal cutoffs of waist circumference were 88 cm for men and 82 cm for women, and those of BMI were 25.0 kg m -2 for both genders (Table 3).…”

Section: Resultsmentioning

confidence: 99%

Identification of waist circumference cutoffs for abdominal obesity in the Chinese population: a 7.8-year follow-up study in the Shanghai urban area

Bao

Hou

et al. 2009

Int J Obes

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Aim: To identify the appropriate visceral adipose tissue (VAT) cutoff values for the diagnosis of abdominal obesity in predicting diabetes and the corresponding waist circumference in the Chinese population. Methods: At baseline, 381 volunteers aged 35-75 years were enrolled without diabetes from the Shanghai urban area. Anthropometry and VAT area determined by magnetic resonance imaging were measured. During the average 7.8 years of follow-up, glucose tolerance was monitored. Receiver operating characteristic (ROC) curve analysis was used to define the optimal cutoff points for abdominal obesity. Results: At the end of the study, 290 participants were followed up, in which 63 participants developed diabetes. Using ROC curve analyses in participants with normal glucose regulation, the appropriate VAT cutoff was 90 cm 2 for both genders to predict diabetes development. In logistic regression models, the relative risks (95% confidence intervals) of VAT value over 90 cm 2 were 3.35 (1.10-10.18, P ¼ 0.033) in men and 4.57 (1.73-12.07, P ¼ 0.002) in women after adjusted for age, impaired glucose regulation, hypertension and dyslipidemia. The optimal waist circumference cutoffs were 88 cm for men and 82 cm for women to indicate VAT value over 90 cm 2 in ROC analyses. Conclusion: VAT cutoff of 90 cm 2 is useful for defining visceral obesity in Chinese individuals. The appropriate waist circumference cutoffs for abdominal obesity are 88 cm for men and 82 cm for women in the Chinese population.

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“…According to the population-based longitudinal study in China, standardized prevalences have reached up to 32.4 % for overweight and 9.1 % for obese population [11]. For such a common disorder, the understanding of its adverse effects should not be confined within just cardiovascular comorbidities.…”

Section: Discussionmentioning

confidence: 99%

Impact of body mass on recurrence and progression in Chinese patients with Ta, T1 urothelial bladder cancer

Zhu

Wang

et al. 2015

Int Urol Nephrol

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Risk factors for overweight and obesity, and changes in body mass index of Chinese adults in Shanghai

Cited by 74 publications

References 35 publications

Association of serum 25-hydroxyvitamin D with insulin resistance and β-cell function in a healthy Chinese female population

Association of serum 25-hydroxyvitamin D with insulin resistance and β-cell function in a healthy Chinese female population

Identification of waist circumference cutoffs for abdominal obesity in the Chinese population: a 7.8-year follow-up study in the Shanghai urban area

Impact of body mass on recurrence and progression in Chinese patients with Ta, T1 urothelial bladder cancer

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