Risk Factors for Osteoporosis in Postmenopausal Women

Bijelic, Radojka; Miličević, Snježana; Balaban, Jagoda

doi:10.5455/medarh.2017.71.25-28

Cited by 110 publications

(90 citation statements)

References 19 publications

(18 reference statements)

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“…The pathogenesis of bone loss in HIV-infected individuals is a complex and multifactorial process, with HIV itself, the use of antiretroviral agents, hypogonadism in men, menopause in women, low body mass index (BMI), aging, malnutrition, steroid use, and smoking all associated with bone disease [2]. Hormonal changes in postmenopausal women or in elderly people are associated changes in the bone remodeling cycle, which leads to bone fragility and an increased risk of bone fracture [3,4].…”

Section: Introductionmentioning

confidence: 99%

Trabecular bone scores in young HIV-infected men: a matched case-control study

Kim

Kang

Shin

et al. 2020

BMC Musculoskelet Disord

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Background: Screening for osteoporosis with dual-energy X-ray absorptiometry (DXA) is recommended for male HIV-infected patients only above the age of 50. Recently, trabecular bone score (TBS) has been introduced as a novel tool to assess bone microarchitecture using DXA of the lumbar spine. Few studies have reported TBS values in HIV-infected individuals younger than 50 years of age. This study compared TBS values in young males infected with HIV and matched controls, and investigated the associations between TBS and demographic parameters, clinical parameters, and bone mineral density (BMD) scores. Methods: A cross-sectional study of BMD and TBS in HIV-infected men (n = 80) aged between 18 and 50 years and age-and sex-matched controls (n = 80) was conducted. Results: The proportion of patients with low BMD (Z-score ≤ − 2) was significantly greater among HIV-infected patients than among matched controls (21.3% [17/80] vs. 8.8% [7/80], p = 0.027). Mean TBS values were significantly lower in HIV-infected patients than in controls (1.41 ± 0.07 vs. 1.45 ± 0.07, p = 0.008). In both groups, TBS values were positively correlated with BMD at the lumbar spine, femoral neck, and total hip (p < 0.001); however, TBS was not correlated with body mass index. In the HIV group, TBS was negatively correlated with the duration of tenofovir disoproxil fumarate(TDF) exposure (p = 0.04). Conclusion: Young men infected with HIV had abnormal bone trabecular microarchitecture, as assessed by both TBS and BMD. TBS values were correlated with both BMD and the duration of TDF exposure.

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Section: Introductionmentioning

confidence: 99%

Trabecular bone scores in young HIV-infected men: a matched case-control study

Kim

Kang

Shin

et al. 2020

BMC Musculoskelet Disord

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“…Smoking has been firmly associated independently with osteoporosis by a plethora of studies 16,17 . Baccaro LF.…”

Section: ) Smokingmentioning

confidence: 99%

Could treating periodontitis prevent osteoporosis? An update of the last decade

Skoufou¹,

Yavropoulou²,

Zafeiris³

2019

JRPMS

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Periodontitis has often been reported as a systematic disease independently associated with a range of AbstractChronic periodontitis and osteoporosis are both systemic diseases, characterized by bone resorption. Over the last decade, their correlation has been examined closely, mainly to investigate whether they present a risk factor or an indicator for each other. It is their pathogenetic similarities, their numerous common risk factors and their frequent concomitant development that initiated researchers' interest in the precise association between these two maladies. The present review is aiming to analyse this correlation, laying emphasis on the effects of periodontal status on the skeletal bone mineral density, as suggested by the latest studies. It will also attempt to clarify whether periodontal management could influence the progression or the onset of osteoporosis.

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“…The pathogenesis of bone loss in HIV-infected individuals is a complex and multifactorial process, with HIV itself, the use of antiretroviral agents, hypogonadism in men, menopause in women, low body mass index (BMI), aging, malnutrition, steroid use, and smoking all associated with bone disease [2]. Hormonal changes in postmenopausal women or in elderly people are associated changes in the bone remodeling cycle leading to bone fragility and increased risk of bone fracture [3,4].…”

Section: Introductionmentioning

confidence: 99%

Trabecular bone scores in young HIV-infected men: a matched case-control study

Kim

Kang

Shin

et al. 2019

Preprint

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Background Screening for osteoporosis with dual-energy X-ray absorptiometry (DXA) is recommended for male HIV-infected patients only above the age of 50. Recently, trabecular bone score (TBS) has been introduced as a novel tool to assess bone microarchitecture using DXA of the lumbar spine. Few studies have reported TBS values in HIV-infected individuals younger than 50 years of age. This study compared TBS values in young males infected with HIV and matched controls, and investigated the associations between TBS and demographic parameters, clinical parameters, and bone mineral density (BMD) scores. Methods A cross-sectional study of BMD and TBS in HIV-infected men (n = 80) aged between 18 and 50 years and age- and sex-matched controls (n = 80) was conducted. Results The proportion of patients with low BMD (Z-score ≤−2) was significantly greater among HIV-infected patients than among matched controls (21.3% [17/80] vs. 8.8% [7/80], p = 0.027). Mean TBS values were significantly lower in HIV-infected patients than in controls (1.41 ± 0.07 vs. 1.45 ± 0.07, p = 0.008). In both groups, TBS values were positively correlated with BMD at the lumbar spine, femoral neck, and total hip (p < 0.001); however, TBS was not correlated with body mass index. In the HIV group, TBS was negatively correlated with the duration of tenofovir disoproxil fumarate(TDF) exposure (p = 0.04). Conclusion Young men infected with HIV had abnormal bone trabecular microarchitecture, as assessed by both TBS and BMD. TBS values were correlated with both BMD and the duration of TDF exposure.

show abstract

Risk Factors for Osteoporosis in Postmenopausal Women

Cited by 110 publications

References 19 publications

Trabecular bone scores in young HIV-infected men: a matched case-control study

Trabecular bone scores in young HIV-infected men: a matched case-control study

Could treating periodontitis prevent osteoporosis? An update of the last decade

Trabecular bone scores in young HIV-infected men: a matched case-control study

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