Risk Factors for Motor Vehicle Collisions in Patients with Primary Open-Angle Glaucoma: A Multicenter Prospective Cohort Study

Yuki, Kenya; Awano-Tanabe, Sachiko; Ono, Takaaki; Shiba, Daisuke; Murata, Hiroshi; Asaoka, Ryo; Tsubota, Kazuo

doi:10.1371/journal.pone.0166943

Cited by 9 publications

(16 citation statements)

References 24 publications

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“…Glaucoma is characterized by progressive optic neuropathy that could lead to visual function damage including VF defects and VA decrease [18]. Ophthalmologists paid close attention to these objective visual function indices in clinical practice.…”

Section: Discussionmentioning

confidence: 99%

Anxiety and Depression in Glaucoma Patients and its Correlations with Vision-related Quality of Life and Objective Visual Function Indices

Kong

Sun

2020

Preprint

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Background: To investigate anxiety and depression in glaucoma patients and its correlations with vision-related quality of life (VR-QoL) and objective visual function indices.Methods: In this cross-sectional study, the Hospital Anxiety and Depression Scale (HADS) and the 25-item National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) questionnaires were administered to 446 Chinese glaucoma patients to assess their psychological disorders, namely anxiety and depression, and VR-QoL, respectively. Socio-demographic and clinical data were collected at the same time. Multivariate linear regression analysis was carried out to investigate the associations between VR-QoL, visual function indices and psychological disorders. Standardized partial regression analysis was used to identify the variable mostly indicative in evaluating psychological burdens. Results: The prevalence of anxiety and depression in Chinese glaucoma patients was 12.11% and 25.78%, respectively. Most of the subscales and the composite score of NEI VFQ-25 were negatively associated with each of anxiety and depression after adjusting for socio-demographic and clinical variables. For visual function indices, only the best corrected visual acuity of both eyes was correlated with anxiety after adjustment. Standardized partial regression analysis further showed VR-QoL but not the objective visual function indices mostly relevant to psychological disturbances. Conclusions: Anxiety and depression were common in Chinese glaucoma patients. Self-reported VR-QoL was beneficial in assessing glaucoma patients’ psychological disorders, while objective visual function indices provide little hint on it.

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Section: Discussionmentioning

confidence: 99%

Anxiety and Depression in Glaucoma Patients and its Correlations with Vision-related Quality of Life and Objective Visual Function Indices

Kong

Sun

2020

Preprint

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“…This study consisted of a baseline cross-sectional study and a 3-year follow-up prospective cohort study. Descriptive research design, baseline evaluation of subjects with glaucoma, diagnostic criteria for POAG, and exclusion criteria were shown in our previous paper [ 11 , 12 ]. This is a sub-analysis of our two previous reports.…”

Section: Methodsmentioning

confidence: 99%

Association between glaucoma severity and driving cessation in subjects with primary open-angle glaucoma

et al. 2018

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BackgroundThe aim of this study, which included a baseline cross-sectional study and a 3-year follow-up prospective study, was to investigate the association between glaucomatous visual field damage and driving cessation in subjects with primary open-angle glaucoma (POAG).MethodsA total of 211 POAG subjects divided into 3 groups according to POAG severity (mild, moderate, or severe) in the better eye were enrolled along with 148 control subjects; subjects were asked about changes in their driving status. In the 3-year follow-up study, 185 of the POAG subjects and 80 of the controls annually reported their driving status. Adjusted odds ratios and 95% confidence intervals for the prevalence and incidence of driving cessation were estimated with a multiple logistic regression model.ResultsIn the original cross-sectional study, 11/148 (7%) members of the control group reported having given up driving over the previous 5 years; the corresponding figures for the mild POAG, moderate POAG, and severe POAG groups were 9/173 (5%), 0/22 (0%), and 5/16 (31%), respectively (p = 0.001, Fisher’s exact test), with severe POAG found to be associated with driving cessation after adjustment for age, gender, systemic hypertension, and diabetes mellitus (odds ratio 11.52 [95% CI 2.87-46.35], ref. control, p = 0.001). In the follow-up study, the proportions of subjects who ceased driving were 1/80 (1.3%) in the control group, 8/152 (5.3%) in the mild POAG group, 5/22 (22.7%) in the moderate POAG group, and 2/11 (18.2%) in the severe POAG group (p = 0.001, Fisher’s exact test). Moderate POAG and severe POAG in the better eye were found to be associated with driving cessation after adjustment for age, gender, systemic hypertension, and diabetes mellitus (moderate POAG in the better eye: odds ratio 37.7 [95% CI 3.7-383.8], ref. control, p = 0.002, and severe POAG in the better eye: odds ratio 52.8 [95% CI 3.5-797.0], ref. control, p = 0.004).ConclusionModerate and Severe POAG in the better eye is associated with driving cessation.

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“…Recently, a prospective, multicenter study showed that the visual acuity of the worst eye is a significant risk factor for MVCs in patients with primary open-angle glaucoma (34) . Conversely, Gracitelli and colleagues found in a prospective study that the visual acuities of both best and worst eye were not predictive factors of MVCs (35) .…”

Section: Visual Acuity and Ability To Drivementioning

confidence: 99%

Assessing driving risk in patients with glaucoma

Correa¹,

Medeiros²,

Abe³

et al. 2019

Arquivos Brasileiros De Oftalmologia

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Glaucoma is the leading cause of irreversible blindness worldwide and can affect a broad array of daily activities, including driving. Recently, studies investigating the relationship between driving performance and glaucoma have received a great deal of interest. Assessment of driving behavior is not straightforward because driving is a complex skill involving significant multi-tasking ability. In this review, we summarize recent work from clinical studies investigating how glaucoma can affect driving performance. Patients with glaucoma are more likely to be involved in motor vehicle collisions when compared to healthy subjects. Here we describe how conventional functional tests performed in glaucoma patients, such as visual field measure ments via standard automatic perimetry, are associated with driving performance. However, the risk of motor vehicle collisions is not entirely attributable to visual field impairment in glaucoma, suggesting that other factors also account for both driving safety and performance. Finally, we show different studies suggesting that parameters from driving simulators can be helpful because they can identify the impact of visual loss on complex situations.

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Risk Factors for Motor Vehicle Collisions in Patients with Primary Open-Angle Glaucoma: A Multicenter Prospective Cohort Study

Cited by 9 publications

References 24 publications

Anxiety and Depression in Glaucoma Patients and its Correlations with Vision-related Quality of Life and Objective Visual Function Indices

Anxiety and Depression in Glaucoma Patients and its Correlations with Vision-related Quality of Life and Objective Visual Function Indices

Association between glaucoma severity and driving cessation in subjects with primary open-angle glaucoma

Assessing driving risk in patients with glaucoma

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