Purpose
Pseudomonas aeruginosa bacteremia presents a severe challenge to hospitalized patients. However, to date, the risk factors for mortality among inpatients with
P. aeruginosa
bacteremia in China remain unclear.
Patients and Methods
This retrospective multicenter study was performed to analyze 215 patients with culture-confirmed
P. aeruginosa
bacteremia in five healthcare centers in China during the years 2012–2019.
Results
Of 215 patients with
P. aeruginosa
bacteremia, 61 (28.4%) died during the study period. Logistic multivariable analysis revealed that cardiovascular disease (OR=3.978,
P
=0.001), blood transfusion (OR=5.855,
P
<0.001) and carbapenem-resistant
P. aeruginosa
(CRPA) phenotype (OR=4.485,
P
=0.038) constituted the independent risk factors of mortality. Furthermore, both CRPA and multidrug-resistant
P. aeruginosa
(MDRPA) phenotypes were found to be significantly associated with 5-day mortality (Log-rank,
P
<0.05).
Conclusion
This study revealed a high mortality rate amongst hospitalized patients with
P. aeruginosa
bacteremia, and those with cardiovascular diseases, CRPA and MDRPA phenotypes, should be highlighted and given appropriate management in China.