Risk Factors for Maternal Body Mass Index and Gestational Weight Gain in Twin Pregnancies

Abstract

Objective This retrospective cohort study analyzes risk factors for abnormal pre-pregnancy body mass index and abnormal gestational weight gain in twin pregnancies. Methods Data from 10 603/13 682 twin pregnancies were analyzed using uni- and multivariable logistic regression models to determine risk factors for abnormal body mass index and weight gain in pregnancy. Results Multiparity was associated with pre-existing obesity in twin pregnancies (aOR: 3.78, 95% CI: 2.71 – 5.27). Working in academic or leadership positions (aOR: 0.57, 95% CI: 0.45 – 0.72) and advanced maternal age (aOR: 0.96, 95% CI: 0.95 – 0.98) were negatively associated with maternal obesity. Advanced maternal age was associated with a lower risk for maternal underweight (aOR: 0.95, 95% CI: 0.92 – 0.99). Unexpectedly, advanced maternal age (aOR: 0.98, 95% CI: 0.96 – 0.99) and multiparity (aOR: 0.6, 95% CI: 0.41 – 0.88) were also associated with lower risks for high gestational weight gain. Pre-existing maternal underweight (aOR: 1.55, 95% CI: 1.07 – 2.24), overweight (aOR: 1.61, 95% CI: 1.39 – 1.86), obesity (aOR: 3.09, 95% CI: 2.62 – 3.65) and multiparity (aOR: 1.64, 95% CI: 1.23 – 2.18) were all associated with low weight gain. Women working as employees (aOR: 0.85, 95% CI: 0.73 – 0.98) or in academic or leadership positions were less likely to have a low gestational weight gain (aOR: 0.77, 95% CI: 0.64 – 0.93). Conclusion Risk factors for abnormal body mass index and gestational weight gain specified for twin pregnancies are relevant to identify pregnancies with increased risks for poor maternal or neonatal outcome and to improve their counselling. Only then, targeted interventional studies in twin pregnancies which are desperately needed can be performed.

Impact of maternal body mass index and gestational weight gain on maternal and neonatal outcomes in twin pregnancies

“…Our results do inform, however, on the need of increased awareness on the significance of the effect of low or high maternal GWG on pregnancy outcomes and the importance of patient counseling on nutrition in pregnancy. Identifying the risk factors for abnormal BMI and GWG in twin pregnancies can help target the counseling concerning nutrition and physical activity for women who will most benefit 19 …”

“…Identifying the risk factors for abnormal BMI and GWG in twin pregnancies can help target the counseling concerning nutrition and physical activity for women who will most benefit. 19 In 2016, Whitaker et al found that only 52% of women with singleton pregnancies received advice on optimal GWG. 20 Women pregnant with twins were only counseled with respect to physical activity in 74.5% and to nutrition in 62.7%.…”

“…Identifying the risk factors for abnormal BMI and GWG in twin pregnancies can help target the counseling concerning nutrition and physical activity for women who will most benefit. 19 …”