Risk factors for infectious complications following transrectal ultrasound-guided prostate biopsy

Wu, Yupeng; Li, Xiaodong; Ke, Zhi‐Bin; Chen, Shao‐Hao; Chen, Ping-Zhou; Wei, Yong; Huang, Jiaofeng; Sun, Xiong‐Lin; Xue, Xue-Yi; Zheng, Qing‐Shui; Xu, Ning

doi:10.2147/idr.s171162

Cited by 21 publications

(20 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…STURS-PB has been described in previous research. 16,17 The clinical data, including the PSA levels1, the fPSA levels, the prostate volume, the fPSA/TPSA ratio, the PSAD, transrectal ultrasound, DRE and MP-MRI, were collected and analyzed. The TPSA and fPSA levels are determined by the chemiluminescence method.…”

Section: Sturs-pb and Clinical Data Collectionmentioning

confidence: 99%

<p>The Value of Prostate-Specific Antigen-Related Indexes and Imaging Screening in the Diagnosis of Prostate Cancer</p>

Bai¹,

Jiang²,

Zhang³

et al. 2020

CMAR

View full text Add to dashboard Cite

The aim of this study was to explore the value of the prostate-specific antigen (PSA) levels, the ratio of free PSA to total PSA (fPSA/TPSA), the PSA density (PSAD), digital rectal examination (DRE), transrectal prostate ultrasound (TRUS), and multiparameter MRI (MP-MRI) in the differential diagnosis of benign prostatic hyperplasia (BPH) and prostate cancer (PCa). Methods: From February 2016 to September 2019, data from 620 patients who underwent systematic transrectal ultrasound-guided prostate biopsy (STURS-PB) in our hospital were retrospectively collected, including the PSA levels, the fPSA/TPSA ratio, the PSAD, DRE, TRUS, MP-MRI, prostate volume, and other clinical data. Results: Among the 620 patients, 249 patients were in the PCa group, and 371 patients in the BPH group. The positive puncture rate was 40.16%. The positive predictive values of DRE, TRUS, mpMRI, and TPSA levels for PCa were 39.91%, 39.38%, 64.14%, and 41.57%, respectively; the sensitivity of these parameters was 37.35%, 51.41%, 74.69%, and 57.43%, respectively; and the specificity of these parameters was 62.26%, 46.90%, 71.97%, and 45.82%, respectively. When the TPSA concentration was in the range of 4-20 ng/mL, the positive puncture rate of STURS-PB was 23.18%, with a high rate of misdiagnosis. When the TPSA concentration was in the range of 4-20 ng/mL, the fPSA/ TPSA ratio was 0.15, the PSAD was 0.16, the comprehensive evaluation of PCa was optimal (the sensitivity of these parameters was 88.85% and 84.09%, respectively; the specificity was 80.17% and 67.29%, respectively; the positive predictive value was 57.41% and 51.39%, respectively). When the TPSA concentration >4 ng/mL, the fPSA/TPSA ratio ≤0.15 and the PSAD ≥0.16, the sensitivity, specificity, and correctness index of the PCa and BPH diagnosis were 80.54%, 82.75%, and 67.07%, respectively. Conclusion: When using DRE, TRUS, and MP-MRI to screen for PCa, MP-MRI has a relatively high sensitivity and specificity. Using these three thresholds (TPSA >4 ng/mL combined with an fPSA/TPSA ratio ≤0.15 and a PSAD ≥0.16) is significantly better than using TPSA levels alone for the differential diagnosis of PCa and BPH.

show abstract

Section: Sturs-pb and Clinical Data Collectionmentioning

confidence: 99%

<p>The Value of Prostate-Specific Antigen-Related Indexes and Imaging Screening in the Diagnosis of Prostate Cancer</p>

Bai¹,

Jiang²,

Zhang³

et al. 2020

CMAR

View full text Add to dashboard Cite

show abstract

“…Erkoç et al [24] studied 1280 cases for complications after TRUS guided prostate biopsy and observed a 6.5% infective complication rate. Similarly, Wu et al [25] found 8.23% incidence rate for this complication. Infective pathology rate was 7.2% in the present study.…”

Section: Discussionmentioning

confidence: 75%

Factors affecting complications of transrectal ultrasound-guided prostate biopsy: A cohort study with 403 patients in a single center

Kölükçü¹,

Beyhan²,

Atılgan³

2019

Journal of Surgery and Medicine

View full text Add to dashboard Cite

show abstract

“…La PBA, que se produce luego de una biopsia prostática, ocurre debido a que los microorganismos penetran el tejido mediante la inoculación directa de bacterias de la mucosa rectal a través de la aguja de biopsia [2] . Si bien las complicaciones después de una biopsia transrectal son comunes, las complicaciones infecciosas son algunas de las más graves que enfrenta esta población de pacientes [11] . Batura y Gopal Rao [12] informaron que aproximadamente que entre el 2,15% y el 3,6% de los pacientes que se sometieron a biopsia transrectal en Inglaterra y Gales fueron readmitidos por complicaciones infecciosas.…”

Section: Discussionunclassified

Factores asociados a la presencia de prostatitis aguda bacteriana en pacientes sometidos a biopsia prostática transrectal entre los años 2015 y 2019 en un Hospital de las Fuerzas Armadas de Lima, Perú

Collado-Mendiola¹,

Lenz-Lee²,

Alban-Moral³

et al. 2020

Acta Med Peru

View full text Add to dashboard Cite

Objetivo: determinar los factores asociados a la presencia de prostatitis aguda bacteriana en pacientes sometidos a biopsia prostática transrectal entre los años 2015 y 2019 en un Hospital de las Fuerzas Armadas de Lima, Perú. Materiales y métodos: estudio observacional transversal retrospectivo. Se evaluaron historias clínicas de 142 pacientes, seleccionados por muestreo no probabilístico. Analizamos los factores asociados a la presencia de prostatitis aguda bacteriana (PAB) en pacientes sometidos a biopsia prostática transrectal (modelo-1) y el número de factores asociados a PAB (modelo-2). Resultados: la presencia de prostatitis aguda bacteriana (PAB) fue 15,5%. La PAB fue mayor en pacientes diabéticos, hipertensos y los que padecían de insuficiencia renal crónica. En el modelo-1, el antecedente de diabetes mellitus tipo 2 (RPa: 3,18; IC 95%: 0,92 – 11,03), la hipertensión arterial (razón de prevalencia ajustada [RPa]: 1,78; IC 95%: 0,53 – 5,98), la insuficiencia renal (RPa: 2,73; IC 95%: 0,60 – 12,46) y la prostatitis crónica (RPa: 4,5; IC 95%: 0,99 – 20,43) no se encontraron asociados (p >0,05). En el modelo-2, encontramos que aquellos sujetos entre 66-75 años, tienen 50% menor probabilidad de presentar PAB que aquellos sujetos de 50-65 años y que los sujetos mayores de 75 años tienen 2,7 (IC 95%: 0,86 – 8,13) veces mayor probabilidad que el grupo más joven. Finalmente, se observó que un mayor número de comorbilidades incrementa la probabilidad de presentar PAB, siendo 4,80 (IC 95%: 1,86 – 12,42) veces en aquellos con una enfermedad, 5,77 (IC 95%: 1,03 – 32,13) con dos enfermedades y 10,47 (IC 95%: 1,98 – 55,41) veces mayor, en aquellos con tres enfermedades. Conclusiones: en nuestro estudio, el antecedente de diabetes mellitus tipo 2 y el número de comorbilidades crónicas incrementan la probabilidad de presentar PAB. Se recomienda realizar un mayor número de estudios que permitan verificar nuestros resultados.

show abstract

Risk factors for infectious complications following transrectal ultrasound-guided prostate biopsy

Cited by 21 publications

References 36 publications

<p>The Value of Prostate-Specific Antigen-Related Indexes and Imaging Screening in the Diagnosis of Prostate Cancer</p>

<p>The Value of Prostate-Specific Antigen-Related Indexes and Imaging Screening in the Diagnosis of Prostate Cancer</p>

Factors affecting complications of transrectal ultrasound-guided prostate biopsy: A cohort study with 403 patients in a single center

Factores asociados a la presencia de prostatitis aguda bacteriana en pacientes sometidos a biopsia prostática transrectal entre los años 2015 y 2019 en un Hospital de las Fuerzas Armadas de Lima, Perú

Contact Info

Product

Resources

About