Risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people: a retrospective cohort study

Abstract

BACKGROUND: Advanced age, multiple chronic diseases and frailty have been correlated with worse prognosis among coronavirus disease 2019 (COVID-19) inpatients. OBJECTIVE: To investigate potential risk factors for hospitalization and death due to COVID-19 among frail community-dwelling elderly people. DESIGN AND SETTING: Retrospective cohort study of patients followed up at a geriatric outpatient clinic in Belo Horizonte, Minas Gerais, Brazil. METHODS: The associations of demographic characteristics (age and sex) and clinical characteristics (frailty, multimorbidity, number of medications with long-term use, obesity, smoking, diabetes mellitus, pulmonary diseases, cardiovascular diseases, cerebrovascular disease, and chronic kidney disease) with the risk of hospitalization and death due to COVID-19 were explored using a multivariable logistic regression model. RESULTS: 5,295 patients (mean age 78.6 ± 9.4 years; 72.6% females) were included. After adjustments, the number of medications with long-term use was found to increase the odds of hospitalization due to COVID-19 (odds ratio, OR: 1.13; 95% confidence interval, CI: 1.06-1.22). Frailty, multimorbidity and diabetes mellitus also increased the odds of hospitalization (

Fragilidade em pessoas idosas com Diabetes Mellitus e fatores associados: estudo longitudinal

“…Esta síndrome é caracterizada por uma incapacidade de o organismo lidar com os agentes estressores, elevando o risco de incapacidades. A ocorrência concomitante da fragilidade e DM pode elevar as chances de complicações graves para a pessoa idosa, além de comprometer o desenvolvimento das AVD e AIVD 18,19 .…”

Curso Intra-Hospitalar De Idosos Com Covid-19

“…Em uma coorte com 5295 pacientes no Brasil com idade média de 78,6 anos ± 9,4 anos mostrou que a fragilidade, múltiplas comorbidades, uso prolongado de medicamentos, obesidade (IMC>30) e tabagismo são fatores que aumentam o risco de hospitalização por COVID-19 no paciente idoso, sendo a Diabete Mellitus principal fator para aumento da mortalidade (AZEVEDO et al,2022). FANG et al,2020).…”