Risk Factors for Dry Eye in Mainland China: A Multi-Center Cross-Sectional Hospital-Based Study

Zhang, Shuang; Hong, Jing

doi:10.1080/09286586.2019.1632905

Cited by 21 publications

(17 citation statements)

References 31 publications

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“…A large number of studies [ 9 – 16 ] have shown that the major risk factors for DED include female gender, older age, medication intakes for treatment of systemic diseases, prolonged using of visual display, corneal refractive surgery, and the use of contact lens. In our study, we revealed that older age was significantly associated with a higher risk of DES, which was consistent with the findings reported by Stapleton et al [ 4 ] Surprisingly, we also found that wearing protective glasses was correlated with a lower risk of DES among the participated medical staff.…”

Section: Discussionmentioning

confidence: 99%

Investigation of dry eye symptoms of medical staffs working in hospital during 2019 novel coronavirus outbreak

et al. 2020

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The aim of this study was to survey the prevalence of dry eye symptoms (DES) among doctors and nurses in the period of 2019, novel coronavirus (COVID-19) outbreak. To evaluate the DES of doctors and nurses worked at front-line hospitals with protective glasses for a mean time of 4 to 6 hours, a questionnaire developed by the researchers with the Ocular Surface Disease Index (OSDI) was used. These data were evaluated using descriptive statistics and correlation test with SPSS 22.0. The study included 13 doctors and 40 nurses, among which 16 were male and 37 were female, and the mean age of the participants was 32.43 ± 5.15 years old. According to the OSDI scores, 64.15, 24.52, 7.54, and 3.77% of the participants experienced occasional, mild, moderate, and severe DES, respectively. The factors significantly correlated with OSDI scores were age and duration of wearing protective glasses, while the duration of wearing protective glasses may be a protective factor of dry eye symptoms. Our study showed that most of the doctors and nurses worked at the front-line of combating COVID-19 did not experience DES, while the symptoms of those who experienced DES might be improved by wearing protective glasses.

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Section: Discussionmentioning

confidence: 99%

Investigation of dry eye symptoms of medical staffs working in hospital during 2019 novel coronavirus outbreak

et al. 2020

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“…With the improvement in people's life and accelerated population aging, the prevalence of DED increases gradually. Currently, the global prevalence of DED ranges from 5 to 50% ( 3 ), and it is about 21–58% in China ( 4 , 5 ). As a common ocular disease, DED affects patients' health and quality of life, and has even been associated with increased prevalence of depression ( 6 ).…”

Section: Introductionmentioning

confidence: 99%

Benefits and Safety of Astaxanthin in the Treatment of Mild-To-Moderate Dry Eye Disease

Tian

Wen

et al. 2022

Front. Nutr.

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Objectives: To evaluate the effect of astaxanthin in the treatment of mild-to-moderate dry eye disease (DED) in middle-aged and elderly patients.Methods: 120 eyes of 60 middle-aged and elderly patients with mild-to-moderate DED were enrolled in this prospective, one-group, quasi-experimental study. Six milligram Astaxanthin tablets (Weihong Haematococcus Pluvialis Astaxanthin, Hangzhou Xinwei Low Carbon Technology R&D Co., Ltd., China) were administered orally, twice daily for 30 ± 2 days. History of eye diseases, treatment, systemic disease, and medication before the test were recorded. In addition, the ocular surface disease index (OSDI) questionnaire, non-invasive tear break-up time (NIBUT), fluorescein break-up time (FBUT), corneal fluorescein staining (CFS) score, eyelid margin signs, meibomian gland (MG) expressibility, meibum quality, meibomian gland dropout (MGDR), Schirmer I test (SIt), tear meniscus height (TMH), bulbar conjunctiva congestion degree, blink frequency, incomplete blink rate, and thickness of tear film lipid layer were collected before treatment, 2 weeks after the initiation of treatment, and at the end of treatment. Visual acuity (VA), intraocular pressure (IOP), anterior segment, fundus, discomfort symptoms and other adverse reactions were also monitored throughout the study to assess the safety.Results: OSDI score, NIBUT, BUT, CFS score, eyelid margin signs, MG expressibility, meibum quality, and blink frequency improved significantly to varying degrees after treatment compared with those before the treatment (P < 0.05), while TMH, SIt, conjunctival congestion, the thickness of tear film lipid layer, MGDR, incomplete blink rate, VA and IOP did not differ (P > 0.05).Conclusions: Oral administration of astaxanthin improves the symptoms and signs of middle-aged and elderly patients with mild-to-moderate DED.

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“…Female gender, higher age, medications, Asian race and environmental exposure contribute to the increasing risk of DED. [ 2 , 3 ] In fact, DED has became the perplex of the patients, who have to seek help from ophthalmologist. [ 4 ]…”

Section: Introductionmentioning

confidence: 99%

Effect of acupuncture versus artificial tears for dry eye disease

Wang

Zhang

et al. 2020

Medicine

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Background: The global prevalence of dry eye disease (DED) ranged from 5% to 50%, accompanied by the yearly increasing trend and younger onset. To date artificial tear serves as a mainstay therapy for DED management. It is noteworthy that, acupuncture has been accepted for treating DED with a time-honored history in China. However, no systematic review has been updated till now, which is focusing on comparing acupuncture vs. artificial tears for DED management. Methods: Eight databases will be searched with the language restrictions of English and Chinese from their inception to July 1, 2020. Randomized controlled trials comparing acupuncture versus artificial tears for DED treatment were enrolled. Identification, research inclusion, data extraction and assessment of the risk of bias were conducted independently by 2 or more reviewers. The primary outcomes were Schirmer I test and tear break-up time. We used Review Manager Software (v.5.3) for assessing the risk of bias and all statistical analyses. Results: Based on the evidence obtained, whether the effect of acupuncture was equal to or even better than that of artificial tear therapy in the treatment of DED would be elaborated. Conclusion: In summary, this review would provide a relatively convincing conclusion on whether acupuncture deserves to be recommended as an adjunct treatment for DED, so as to propose some significant insights for the doctors handling with DED. OSF Registration number: 10.17605/OSF.IO/Z28M6.

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Risk Factors for Dry Eye in Mainland China: A Multi-Center Cross-Sectional Hospital-Based Study

Cited by 21 publications

References 31 publications

Investigation of dry eye symptoms of medical staffs working in hospital during 2019 novel coronavirus outbreak

Investigation of dry eye symptoms of medical staffs working in hospital during 2019 novel coronavirus outbreak

Benefits and Safety of Astaxanthin in the Treatment of Mild-To-Moderate Dry Eye Disease

Effect of acupuncture versus artificial tears for dry eye disease

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