Risk factors for drug-related problems in elderly ambulatory patients

Catania, Patrick N.

doi:10.1016/s1084-628x(98)90150-2

Cited by 6 publications

(3 citation statements)

References 3 publications

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“…Residents of RACFs are more likely to have multiple comorbidities, which leads to the use of medications classed as “high risk.” 12 The dose relationship between anticholinergic and sedative medicines and falls has not been examined in older people living in RACFs. The aim of this study was to evaluate the association between higher DBI and fall rates in a population of older people living in RACFs.…”

mentioning

confidence: 99%

Associations Between Drug Burden Index and Falls in Older People in Residential Aged Care

Wilson

Hilmer

March

et al. 2011

Journal of the American Geriatrics Society

193

181

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confidence: 99%

Associations Between Drug Burden Index and Falls in Older People in Residential Aged Care

Wilson

Hilmer

March

et al. 2011

Journal of the American Geriatrics Society

193

181

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“…Particularly with older patients; it has been known that they tend to experience multiple practical problems using their medicines such as difficulty reading and understanding the instruction, handling the packaging, preparation before use, and taking the medicine; all of which have the potential to cause negative impacts on their health [9, 10]. On the other hand, the ageing population is more prone to chronic diseases and is more likely to be prescribed multiple medications [11–13]. Additionally, inappropriate MMP has been linked with a decline in the cognitive functioning of older patients [14].…”

Section: Introductionmentioning

confidence: 99%

Factors predicting home medication management practices among chronically ill older population of selected districts of Nepal

Shrestha

Poudel

Pradhan³

et al. 2019

BMC Geriatr

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Background Older population often have multiple and complex needs that are consequently challenged by the presence of polypharmacy, adverse drug reactions and drug-drug interaction. We aimed to determine home medication management practices (MMP) and its associated factors among chronically ill older population of selected districts of Nepal. Methods A community based cross-sectional survey was conducted among 386 chronically ill older individuals from selected areas of Nepal between April to September 2016. Appropriateness of MMP was assessed through scores of questions using interview method. Multivariate logistic regression analysis using potential variables from bivariate analysis were used to determine factors affecting MMP. Results The overall home MMP was mostly inappropriate (80.1%). Most participants had multiple prescribers for single disease (202, 52.3%) and inappropriate medication storage (188, 48.7%). Though the majority of them had drug administration schedule (378, 97.9%), expired medicines were also used (2, 0.5%). Regression analysis showed less than one year duration of disease (odds ratio [OR] = 3.901, 95% confidence interval [CI] = 1.528 to 9.959, P = 0.004), 1–2 years duration of disease (OR = 2.415, 95% CI = 1.210 to 4.821, P = 0.012) and smokers (OR = 2.025, 95% CI = 1.036 to 3.956, P = 0.039) as the major factors affecting appropriate home MMP. Conclusions The home MMP was associated with duration of disease and smoking status among chronically ill older patients living in selected districts of Nepal. Proper counselling and monitoring of such patients might be necessary to improve the practice. Electronic supplementary material The online version of this article (10.1186/s12877-019-1081-7) contains supplementary material, which is available to authorized users.

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“…There is very little evidence on the efficacy of medicines in older people living in RACFs. These people have a high risk of adverse drug events (ADEs) as they are likely to have multiple cormorbidities and, hence, multiple medicines, including medicines of a high-risk category [Catania, 1998; Harms and Garrard, 1998]. It is therefore paramount that drug safety, initiated by a multidisciplinary team of health professionals, be a component of patient care in RACFs.…”

Section: Introductionmentioning

confidence: 99%

Medication safety in residential aged-care facilities: a perspective

Wilson

March

Sambrook

et al. 2010

Therapeutic Advances in Drug Safety

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Medication safety must be tailored to the distinctive issues in residential aged-care facilities (RACFs). The health and functional characteristics of their residents are different to those of hospital inpatients and community-dwelling older adults, and there are unique staffing and management issues. Understanding the aetiology and epidemiology of drug-related problems is vital in developing methods to improve patient safety. In this perspective review, we discuss tools that are used to quantify exposure to 'high-risk' medications and their evaluation in residential aged-care settings. Drug withdrawal interventions are described as a potential way to reduce adverse drug events in RACFs. Multidisciplinary professional interventions, education programs and improved communication between health professionals have been shown to improve medication safety in RACFs. Technological advances and other administrative strategies may also improve resident safety. This perspective addresses issues in medication safety facing RACFs and methods to improve the safety of medicines for their residents.

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Risk factors for drug-related problems in elderly ambulatory patients

Cited by 6 publications

References 3 publications

Associations Between Drug Burden Index and Falls in Older People in Residential Aged Care

Associations Between Drug Burden Index and Falls in Older People in Residential Aged Care

Factors predicting home medication management practices among chronically ill older population of selected districts of Nepal

Medication safety in residential aged-care facilities: a perspective

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