2020
DOI: 10.1016/j.ejca.2020.09.035
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Background Cancer patients are thought to have an increased risk of developing severe Coronavirus Disease 2019 (COVID-19) infection and of dying from the disease. In this work, predictive factors for COVID-19 severity and mortality in cancer patients were investigated. Patients and Methods In this large nationwide retro-prospective cohort study, we collected data on patients with solid tumours and COVID-19 diagnosed between March 1 and June 11, 2020. The primary endpoin… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
2

Citation Types

15
174
4
4

Year Published

2021
2021
2022
2022

Publication Types

Select...
8

Relationship

1
7

Authors

Journals

citations
Cited by 131 publications
(197 citation statements)
references
References 29 publications
15
174
4
4
Order By: Relevance
“…The association of PS >=2 with increased risk of death has been already described by the CCC19 cohort study including 928 patients, by the French nationwide cohort study (GCO-002 CACOVID-19) including 1289 patients, and by the Gustave Roussy cohort of 178 patients. 6,9,16 In our study, presence of dyspnea, COVID-19 phenotype >=3, hospitalization, and intensive care unit admission were all significant predictors of increased risk of death.…”
Section: J O U R N a L P R E -P R O O Fsupporting
confidence: 46%
See 2 more Smart Citations
“…The association of PS >=2 with increased risk of death has been already described by the CCC19 cohort study including 928 patients, by the French nationwide cohort study (GCO-002 CACOVID-19) including 1289 patients, and by the Gustave Roussy cohort of 178 patients. 6,9,16 In our study, presence of dyspnea, COVID-19 phenotype >=3, hospitalization, and intensive care unit admission were all significant predictors of increased risk of death.…”
Section: J O U R N a L P R E -P R O O Fsupporting
confidence: 46%
“…As reported in the vast majority of studies, we confirmed the association of age and comorbidities with an increased risk of death. 14,16,24 Poor PS was also associated with an increased risk of death. The association of PS >=2 with increased risk of death has been already described by the CCC19 cohort study including 928 patients, by the French nationwide cohort study (GCO-002 CACOVID-19) including 1289 patients, and by the Gustave Roussy cohort of 178 patients.…”
Section: J O U R N a L P R E -P R O O Fmentioning
confidence: 97%
See 1 more Smart Citation
“…Existing evidence in the general population indicates older individuals and those with comorbid chronic conditions are at higher risk for SARS‐CoV‐2 infection, severe disease, and death 2–5 . Cancer patients may also be at increased risk of adverse outcomes if infected, 6–10 though morbidity and mortality appear to vary across tumor histology and treatment status 11–16 . While recent small studies suggest that pediatric patients with cancer may not be more vulnerable than other children to infection or morbidity from SARS‐CoV‐2, 17,18 other studies suggest that children with hematologic malignancies may have a more severe course of COVID‐19 illness 19 …”
Section: Introductionmentioning
confidence: 99%
“…The risk of death from COVID-19 in patients treated for cancer was overestimated in the first studies [1] . In large European cohorts and a recent meta-analysis, death and severity of COVID-19 were mostly due to patients’ characteristics with low impact of cancer treatments [2] , [3] , [4] . In the French GCO-002 CACOVID-19 cohort ( n = 1289), independent factors associated with death, in multivariate analysis, were male gender, ECOG performance status ≥ 2 and the updated Charlson comorbidity index (ICCa) [2] .…”
mentioning
confidence: 99%