Risk Factors for Central Visual Field Progression in Myopic Patients with Primary Open-Angle Glaucoma

Abstract

Myopia was linked to the development and progression of primary open-angle glaucoma (POAG), on top of causing early central visual field (VF) involvement. The present study investigated the risk factors for central VF progression in myopic patients with POAG. We included 69 myopic patients with POAG with at least 3 years of follow-up and 5 reliable VF examinations. The rates of mean threshold changes at various VF regions were analyzed and clinical variables associated with faster central VF progression were identified using multivariate logistic regression. The presence of disc hemorrhage was associated with faster global (P = 0.013) and central VF progression (P = 0.046). Those tilted discs with lesser absolute degree of optic disc rotation were associated with faster VF progression in inferior-central region (P = 0.040). Comparative results showed those with < 15 degrees of optic disc rotation had faster VF progression in the inferior-central region (P = 0.017). In myopic patients with POAG, the presence of DH and those tilted discs with lesser optic disc rotation were associated with faster central VF progression.