“…Sardinia has been the subject of several studies on longevity, as it is generally considered a suitable setting: i) for genetic studies, due to its geographical and genetic isolation (Cavalli Sforza et al, 1997;Lampis et al, 2000;Fraumene et al, 2003;Pilia et al, 2006;Strait et al, 2009); ii) for studies of cardiovascular diseases (CVD), given the low mortality rates recorded in the island (Caselli & Lipsi, 2006;Muntoni et al, 2009;Scuteri et al, 2009); iii) for researches on centenarians, found to be geographically limited to the inland area of the region Gatti & Salaris, 2004;Orrù, 2011); iv) for studies of oldest ages in male survival in general (Passarino et al, 2001;Poulain et al, 2011).…”