Risk Factors for Carbapenem Resistant Klebsiella pneumoniae Hospital Infection in the Intensive Care Unit

Abstract

Carbapenem-resistant Klebsiella pneumoniae (CR-Kp) has become a major threat to patients in hospitals, increasing mortality, length of stay and costs. e aim of this study was to discover risk factors for the development of hospital infections (HIs) caused by CR-Kp. A prospective cohort study was conducted in the Medical-Surgical Intensive Care Unit of the Clinical Centre in Kragujevac, Kragujevac, Serbia, from January 1, 2011, to December 31, 2015 (OR=1.080; p=0.045); previous use of carbapenems (OR=7.005; p=0.044); previous use of ciprofl oxacin (OR=20.628; p=0.007) and previous use of metronidazole (OR=40.320; p=0.011 p=0.046), dužina primene antibiotske terapije pre nastanka bolničke infekcije (OR=1.080; p=0.045), prethodna upotreba karbapenema (OR=7.005; p=0.044), prethodna upotreba ciprofl oksacina (OR=20.628; p=0.007) i prethodna upotreba metronidazola (OR=40.320; p=0.011

Preventive Nurse Actions and Risk Factors Associated With Health Care Related Infections: A Narrative Review

“…Therefore, the use of mechanical ventilation and the length of time the tube is present constitute the main extrinsic risk factors for the development of respiratory tract infections. 14,40,41,42,21,32,22 As well as the greater risk of infection by resistant bacteria. 42 In addition to the risk factors directed to specific sites, other risk factors stood out as predictors of more frequent infections, such as length of stay in the ICU 14,34,39,17,34,39,17,33,18,20,21,22 , use of invasive devices 44,45,25,30,31,18,19,20,28,46 , advanced age 17,18,19,20,21,22 , comorbidities: diabetes mellitus 14, 47,30,48,49,50 , arterial hypertension 27 , chronic obstructive pulmonary disease 32 and smoking.…”