Risk factors for Brucella seropositivity in goat herds in eastern and western Uganda

Kabagambe, Edmond K.; Elzer, Philip H.; Geaghan, James P.; Opuda-Asibo, J.; Scholl, Daniel; Miller, J. E.

doi:10.1016/s0167-5877(01)00251-3

Cited by 75 publications

(86 citation statements)

References 13 publications

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“…Other explanation might be due to the fact that grazing in communal pastures may facilitate the contact between infected and not infected flocks (Kabagambe et al 2001, Al-Talafhah et al 2003. This situation probably occurs more frequently in larger flocks, because of their size.…”

Section: Resultsmentioning

confidence: 99%

Seroprevalence of sheep and goat brucellosis in the northeast of Portugal

Coelho

Rodrigues

2013

Arch. med. vet.

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RESUMENSe realizó una encuesta para estimar la seroprevalencia de brucelosis ovina y caprina en la región de Trás-os-Montes e Alto Douro, al noreste de Portugal. En total fueron analizados 278.097 pequeños rumiantes distribuidos en 5.466 rebaños pertenecientes a 13 organizaciones de Ganaderos (OPP) fueron analizados. Cuatrocientos ochenta y siete (8,9%) rebaños tenían uno o más animales serológicamente positivos, con valores que oscilaban entre 8,2% y 9,7%. La prevalencia individual fue de 0,44% (IC 95% 0,40-0,48%). No se detectaron diferencias estadísticamente significativas asociadas al tamaño de los rebaños, las especies, la constitución del rebaño, el tipo de producción y la OPP. Basándose en los resultados de esta encuesta, un pequeño porcentaje de animales y un alto porcentaje de los rebaños en el noreste de Portugal fueron serológicamente positivos. Dada la escasez de estudios epidemiológicos sobre la brucelosis en el norte de Portugal, la información sobre la seroprevalencia obtenida en este estudio es importante a la hora de definir medidas de control de la brucelosis en la zona.Palabras clave: Brucella melitensis, pequeños rumiantes, epidemiología, seroprevalencia. SUMMARYA survey to estimate the seroprevalence of ovine and caprine brucellosis was conducted in the region of Trás-os-Montes e Alto Douro, Northeast of Portugal. In total, 278,097 small ruminants and 5,466 flocks from 13 Livestock Farmers Organizations (OPP's) were analysed. Four hundred and eighty seven (8.9%) flocks had one or more serologically positive animals with values ranging between 8.2% and 9.7%. The individual seroprevalence was 0.44% (CI 95% 0.40-0.48%). There were significant differences in seroprevalence rates among herd sizes, species, constitution of herd, production's type and OPP. Based on the results of this survey, a small percentage of animals and a high percentage of flocks in the Northeast of Portugal were serologically positive. Considering the paucity of epidemiological reports on brucellosis in the Northeast of Portugal the information on seroprevalence provided in this study is necessary to define control measures for brucellosis in the area.

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Section: Resultsmentioning

confidence: 99%

Seroprevalence of sheep and goat brucellosis in the northeast of Portugal

Coelho

Rodrigues

2013

Arch. med. vet.

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“…The relatively higher seroprevalence in sheep may be due to the relatively larger herd sizes of sheep compared to goats in Bangladesh. Larger herd sizes have been reported to be significantly associated with brucellosis seropositivity among livestock (Mikolon et al, 1998;Kabagambe et al, 2001;Solorio-Rivera et al, 2007).…”

Section: Discussionmentioning

confidence: 99%

Bayesian estimation of true prevalence, sensitivity and specificity of indirect ELISA, Rose Bengal Test and Slow Agglutination Test for the diagnosis of brucellosis in sheep and goats in Bangladesh

Rahman¹,

Saegerman²,

Berkvens³

et al. 2013

Preventive Veterinary Medicine

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a b s t r a c tThe true prevalence of brucellosis and diagnostic test characteristics of three conditionally dependent serological tests were estimated using the Bayesian approach in goats and sheep populations of Bangladesh. Serum samples from a random selection of 636 goats and 1044 sheep were tested in parallel by indirect ELISA (iELISA), Rose Bengal Test (RBT) and Slow Agglutination Test (SAT). The true prevalence of brucellosis in goats and sheep were estimated as 1% (95% credibility interval (CrI): 0.7-1.8) and 1.2% (95% CrI: 0.6-2.2) respectively. The sensitivity of iELISA was 92.9% in goats and 92.0% in sheep with corresponding specificities of 96.5% and 99.5% respectively. The sensitivity and specificity estimates of RBT were 80.2% and 99.6% in goats and 82.8% and 98.3% in sheep. The sensitivity and specificity of SAT were 57.1% and 99.3% in goats and 72.0% and 98.6% in sheep. In this study, three conditionally dependent serological tests for the diagnosis of small ruminant brucellosis in Bangladesh were validated. Considerable conditional dependence between IELISA and RBT and between RBT and SAT was observed among sheep. The influence of the priors on the model fit and estimated parameter values was checked using sensitivity analysis. In multiple test validation, conditional dependence should not be ignored when the tests are in fact conditionally dependent.

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“…The high regional prevalence of Mycobacterium and Brucella in central African livestock raises concern for the interactions among cattle, sheep, goats, and mountain gorillas. In Uganda and Rwanda, surveys have reported seroprevalence of brucellosis as high as 35% in cattle, and 13-35% in goats (Onekalit 1987;Akakpo et al, 1988;Kabagambe et al, 2001;), with no data available for sheep. In Rwanda, reported tuberculosis prevalence in cattle is 11% (Kabagambe et al, 1988), with no data available for sheep or goats in Rwanda, or for any livestock in Uganda.…”

Section: Domestic Animal Disease As a Threat To Gorilla Survivalmentioning

confidence: 99%