Risk factors for benign ovarian teratomas

Parazzini, Fabio; Vecchia, Carlo La; Negri, Eva; Moroni, S.; Villa, Antonella

doi:10.1038/bjc.1995.127

Cited by 13 publications

(9 citation statements)

References 9 publications

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“…Despite its high prevalence, studies have frequently focused on malignant transformation, because it is the most commonly encountered germ cell neoplasm of the ovaries. Although one previous study showed an increased prevalence of infertility in women with mature cystic teratomas of ovary,15 direct evidence of an association thereof is lacking.…”

Section: Introductionmentioning

confidence: 93%

Preoperative Serum Anti-Mullerian Hormone Level in Women with Ovarian Endometrioma and Mature Cystic Teratoma

et al. 2013

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PurposeTo investigate whether preoperative serum anti-mullerian hormone (AMH) levels are lower in women with ovarian endometrioma and in women with mature cystic teratoma of the ovaries.Materials and MethodsIn a tertiary university hospital, a retrospective case-control study was performed. Serum AMH levels between an advanced (stage III and IV) endometrioma group (n=102) and an age- and body mass index (BMI)-matched control group were compared. Serum AMH levels between an ovarian mature cystic teratoma group (n=48) and age- and BMI-matched controls were also compared.ResultsAbsolute serum AMH and multiples of the median for AMH (AMH-MoM) relevant to Korean standards were lower in the endometrioma group than controls, but this was not statistically significant (mean±SEM, 2.9±0.3 ng/mL vs. 3.3±0.3 ng/mL, p=0.28 and 1.3±0.1 vs. 1.6±0.1, p=0.29, respectively). Specifically, the stage IV endometriosis group (n=51) exhibited significantly lower serum AMH and AMH-MoM (2.1±0.3 vs. 3.1±0.4 ng/mL, p=0.02 and 1.1±0.1 vs. 1.7±0.2, p=0.03, respectively). Serum AMH and AMH-MoM levels were similar between stage III endometriosis and controls (3.7±0.5 vs. 3.4±0.5 ng/mL and 1.6±0.2 vs. 1.5±0.2, respectively), as well as between the mature cystic teratoma group and controls (4.0±0.5 ng/mL vs. 4.0±0.5 ng/mL and 1.6±0.2 vs. 1.6±0.3, respectively). Interestingly, AMH-MoM level was negatively correlated with endometriosis score with statistical significance (r2=0.13, p<0.01).ConclusionIn women with advanced ovarian endometrioma, preoperative serum AMH values tended to be lower than those for age and BMI-matched controls. Notably, stage IV endometrioma appeared to be closely associated with decreased ovarian reserve, even before operation. Clinicians should keep this information in mind before undertaking surgery of ovarian endometrioma.

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Section: Introductionmentioning

confidence: 93%

Preoperative Serum Anti-Mullerian Hormone Level in Women with Ovarian Endometrioma and Mature Cystic Teratoma

et al. 2013

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“…Of the cases, 19 (22%) occurred in nulliparous patients, 3 (3%) occurred in grand multiparous patients, and 30 (34%) cases did not mention parity. 4 Case Reports in Obstetrics and Gynecology 80 cases (91%) were of unilateral dermoid cysts, and 8 cases (9%) were bilateral dermoid cysts. In all these cases, the unruptured contralateral cyst was also removed.…”

Section: Resultsmentioning

confidence: 99%

“…In premenopausal women who present with an ovarian mass, 70% of those are attributed to a dermoid cyst; however, its true incidence is much lower in postmenopausal women at 20% [1]. The incidence is estimated at 10 per 100,000 women per year [4].…”

Section: Introductionmentioning

confidence: 99%

Spontaneously Ruptured Dermoid Cysts and Their Potential Complications: A Review of the Literature with a Case Report

Nikam

Kapurubandara

2020

Case Reports in Obstetrics and Gynecology

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Spontaneous ruptures of dermoid cysts are a rare occurrence due to their thick capsules. This is the first systematic review on spontaneously ruptured dermoid cysts. A comprehensive literature search was performed from PubMed, Google Scholar, and MEDLINE. The cases were analysed for patient demographics, presenting signs and symptoms, imaging modalities used, management methods, and outcomes. The majority of cases report an idiopathic cause with symptoms of abdominal pain, distension, and fever. Computed tomography is the most accurate in detecting ruptured dermoid cysts. We also report a case of a 66-year-old who presented with sudden abdominal pain and a low-grade temperature. Imaging showed a 10 cm well-circumscribed hyperechoic mass consistent with a dermoid cyst with no suggestive signs of rupture. She was planned for a laparoscopic bilateral salpingo-oophorectomy. However, intraoperatively, a ruptured dermoid cyst was found with bowel adhesions and chemical peritonitis as cyst contents covered the entirety of the intra-abdominal cavity. Her operative course was complicated by inadvertent iatrogenic small bowel injury, unsuccessful laparoscopy, needing conversion to laparotomy. Despite their benign nature, complications from ruptured dermoid cysts include peritonitis, bowel obstruction, and abscesses. Surgical management by both laparoscopy and laparotomy is successful, with laparotomies more likely to be performed. Complications have mostly no long-term sequelae.

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“…Recent epidemiological stud ies, however, suggest that only women with decreased fertility and higher education were at increased risk, but provide no satisfactory explanation for this association [10]. Data on the reproductive history and educational sta tus of patients included in this retrospective study were unavailable.…”

Section: Discussionmentioning

confidence: 96%

Ovarian Tumors in Kuwait

Junaid¹,

Hashad²

1996

Med Principles Pract

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After examination of the case histories of 301 primary ovarian neoplasms in the surgical pathology files of four hospitals in Kuwait from 1984 to 1989, we have reviewed and classified these cases as recommended by the WHO Ovarian Tumors Panel. Standard histopathological techniques were supplemented with special stains in order to increase diagnostic accuracy. Benign cystic teratoma was the single most common tumor in the series. Overall, germ cell tumors were more common than epithelial tumors. However, 75.7% of malignant tumors were epithelial. A higher proportion of epithelial tumors, relatively rare in children and adolescents worldwide, was found in patients under 20 years.

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Risk factors for benign ovarian teratomas

Cited by 13 publications

References 9 publications

Preoperative Serum Anti-Mullerian Hormone Level in Women with Ovarian Endometrioma and Mature Cystic Teratoma

Preoperative Serum Anti-Mullerian Hormone Level in Women with Ovarian Endometrioma and Mature Cystic Teratoma

Spontaneously Ruptured Dermoid Cysts and Their Potential Complications: A Review of the Literature with a Case Report

Ovarian Tumors in Kuwait

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