Risk factors for atypical mycobacterial disease in patients with smear positive pulmonary TB

Shaarawy, Hany; Elhawary, Abeer

doi:10.1016/j.ejcdt.2014.02.011

Cited by 1 publication

(3 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Two other studies (21,30) reported that 95.0% and 57.7% of the patients were female, data that corroborate with other authors. (25,27) However, in a study by Zamarioli et al, (22) The latter result, found in the same population as in the present study, shows that the prevalence of the female gender is higher, considering the current rate of 20.8% and pointing out that women are less affected in our region. These data suggest that women in our country are increasingly attentive to preventive care of diseases and, consequently, become less vulnerable to the involvement of NTMPD.…”

Section: ❚ Discussionsupporting

confidence: 54%

“…In a study conducted in 2012, Mycobacterium massiliense and the Mycobacterium simiae complex were dominant. (27) In the region analyzed in the present study, M. kansasii had the highest occurrence (28.5%), followed by M. fortuitum (16.6%). The work performed by the NTM-NET network evaluated data from 62 laboratories in 30 countries distributed over six continents.…”

Section: ❚ Discussionmentioning

confidence: 50%

“…In the present study, information on past PTB was observed in 45.8% of the patients with confirmed cases, numbers close to those reported in a study conducted in Kuwait (42.6%) and also observed by another Brazilian study, (29) in which this is pointed out as the principal risk factor associated with NTMPD (76%). (27,31) As oriented by the Ministry of Health, the non-recording of information on tuberculosis in the past should be done only when the possibilities of investigating the patient's previous history have been exhausted. (32) The disease is present in most patients, considering the X-ray results with pulmonary cavity (16.7%) or with suspected PTB (45.8%).…”

Section: ❚ Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Epidemiological profile and follow-up of patients with pulmonary disease by non-tuberculous mycobacteria in Baixada Santista area, São Paulo

Coelho¹,

Chiou²,

Pedro³

et al. 2022

Einstein (São Paulo)

View full text Add to dashboard Cite

Objective: To present the frequency and species diversity of non-tuberculous mycobacteria, estimate the prevalence of non-tuberculous mycobacterial pulmonary disease, describe the epidemiological profile, and determine the follow-up of patients with non-tuberculous mycobacterial pulmonary disease living in a region with a high burden of tuberculosis. Methods: This a retrospective cohort observational study using data records obtained from the Instituto Adolfo Lutz -Santos and from the São Paulo Sistema de Vigilância de Tuberculose do Estado de São Paulo in the period between 2000 and 2009. The studied variables were: socio-demographic characteristics, current and past history of tuberculosis, aspects related to diagnosis, and treatment and associated diseases. Results: We included 319 non-tuberculous mycobacteria isolates in the study, corresponding to 257 patients. The species Mycobacterium kansasii (28.5%) and Mycobacterium fortuitum (16.6%) presented the higher occurrence. In 10.9% (24) of the patients, there was a criterion for confirming a case of pulmonary disease due to non-tuberculous mycobacteria. In relation to gender and age, male and individuals over 50 years old were the most frequent. Considering the confirmed cases, 47.8% had a past history of tuberculosis. Conclusion: The lack of information about the cases is evident, since pulmonary disease due to non-tuberculous mycobacteria is not mandatory. The therapeutic regimen according to the identified species is fundamental for success in combating the infections caused by non-tuberculous mycobacteria. Besides that, information about the regional epidemiology of pulmonary disease caused by non-tuberculous mycobacteria and the search for associations with other comorbidities are important to establish the correct treatment. In order to improve surveillance of pulmonary diseases by non-tuberculous mycobacteria, we suggest the implantation of a sentinel surveillance and of population-based studies.

show abstract

Section: ❚ Discussionsupporting

confidence: 54%

Section: ❚ Discussionmentioning

confidence: 50%

Section: ❚ Discussionmentioning

confidence: 99%

See 1 more Smart Citation