Risk factors associated with necrotizing fasciitis of the lower limbs: A multicenter case-control study

Pitché, P.; Diata, A.-B.; Faye, Ousmane; Tounkara, Thierno; Niamba, P.; Mouhari-Touré, A.; Ly, Fatimata; Soumah, M.M.; Some-Korsaga, N.; Akakpo, S.; Diané, B.; Cissé, Mohamed; Niang, S.; Traoré, Adama; Saka, Bayaki

doi:10.1016/j.annder.2020.08.056

Annales de Dermatologie et de Vénéréologie

2021

DOI: 10.1016/j.annder.2020.08.056

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Risk factors associated with necrotizing fasciitis of the lower limbs: A multicenter case-control study

P. Pitché

A.-B. Diata

Ousmane Faye

et al.

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Cited by 4 publications

(1 citation statement)

References 26 publications

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“…The following supporting information can be downloaded at: , Table S1: References in the literature-based search for variables. References [ 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 ] are cited in the supplementary materials.…”

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confidence: 99%

Classification Model for Diabetic Foot, Necrotizing Fasciitis, and Osteomyelitis

Kim

Yoo

Lee

et al. 2022

Biology

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Diabetic foot ulcers (DFUs) and their life-threatening complications, such as necrotizing fasciitis (NF) and osteomyelitis (OM), increase the healthcare cost, morbidity and mortality in patients with diabetes mellitus. While the early recognition of these complications could improve the clinical outcome of diabetic patients, it is not straightforward to achieve in the usual clinical settings. In this study, we proposed a classification model for diabetic foot, NF and OM. To select features for the classification model, multidisciplinary teams were organized and data were collected based on a literature search and automatic platform. A dataset of 1581 patients (728 diabetic foot, 76 NF, and 777 OM) was divided into training and validation datasets at a ratio of 7:3 to be analyzed. The final prediction models based on training dataset exhibited areas under the receiver operating curve (AUC) of the 0.80 and 0.73 for NF model and OM model, respectively, in validation sets. In conclusion, our classification models for NF and OM showed remarkable discriminatory power and easy applicability in patients with DFU.

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confidence: 99%

Classification Model for Diabetic Foot, Necrotizing Fasciitis, and Osteomyelitis

Kim

Yoo

Lee

et al. 2022

Biology

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Causative Micro-Organisms in Necrotizing Fasciitis and their Influence on Inflammatory Parameters and Clinical Outcome

Breidung

Malsagova

Loukas

et al. 2023

Surgical Infections

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Cervical Necrotizing Fasciitis in Adults: A Life-Threatening Emergency in Oral and Maxillofacial Surgery

de Leyva,

Dios-Díez,

Cárdenas-Serres

et al. 2024

Surgeries

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Necrotizing fasciitis (NF) is a life-threatening soft-tissue infection affecting the deep fascia and subcutaneous tissue. It is characterized by a fulminant course and high mortality rates. NF of the head and neck is very rare, with most cases being odontogenic in origin. The purpose of this study is to comprehensively review the most important features of cervical necrotizing fasciitis (CNF) in adults and add our experience in the management of this entity. The most common isolated organisms are Streptococcus spp. and Staphylococcus spp. If the infection progresses to descending mediastinitis, the prognosis becomes very poor. Since the initial clinical features can be similar to those of a non-necrotizing deep cervical infection, a high degree of suspicion is critical for an early diagnosis. A computed tomography scan is essential for the diagnosis and to define the extent of the infection/rule out descending mediastinitis. Early and aggressive surgical debridement of all compromised tissue and antibiotic therapy and fluid resuscitation are essential and should not wait for bacterial culture results. Despite prompt and adequate treatment, the mortality of CNF can be as high as 35%.

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Risk factors associated with necrotizing fasciitis of the lower limbs: A multicenter case-control study

Cited by 4 publications

References 26 publications

Classification Model for Diabetic Foot, Necrotizing Fasciitis, and Osteomyelitis

Classification Model for Diabetic Foot, Necrotizing Fasciitis, and Osteomyelitis

Causative Micro-Organisms in Necrotizing Fasciitis and their Influence on Inflammatory Parameters and Clinical Outcome

Cervical Necrotizing Fasciitis in Adults: A Life-Threatening Emergency in Oral and Maxillofacial Surgery

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