Risk factors associated with lifetime suicide attempts in bipolar I patients: findings from a French National Cohort

Azorin, Jean‐Michel; Kaladjian, Arthur; Adida, M.; Hantouche, Elie G.; Hameg, Ahcène; Lancrenon, S.; Akiskal, Hagop S.

doi:10.1016/j.comppsych.2008.07.004

Cited by 80 publications

(58 citation statements)

References 32 publications

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“…As with the bivariate analysis, suicide attempts in women were found to be principally associated with a broken home and sexual abuse/violence in childhood. Our findings on sexual abuse/violence are compatible with several studies: the review findings of Devries and Seguin [28] and the study of Brezo et al [29] on child abuse in a large cohort of school children, the community study of Mullen et al [30], the review of Santa Mina et al [31], studies on bipolar patients [32][33][34] and on substance-dependent patients [35] and, lastly, the twin study of Kendler et al [36], who found that all psychiatric disorders were associated with sexual abuse. Sexual trauma is common among women, as shown by a large investigation of sexually-experienced American young women, where the prevalence rate of childhood sexual abuse (CSA) was 4.6% [37] and is more frequent among women than men [38].…”

Section: Discussionsupporting

confidence: 77%

Suicidality in the prospective Zurich study: prevalence, risk factors and gender

Angst

Hengartner

Rogers

et al. 2014

Eur Arch Psychiatry Clin Neurosci

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Our prospective Zurich study found that suicidal ideation had occurred in 40.5 % and suicide attempts in 6.6 % of the population by age 50. Important gender differences were found in both suicidality and its risk factors. Suicide attempts were earlier and more frequent among women than among men: 70 versus 44 % reported their first suicide attempt before 20. For women, the relative risk of suicide attempts was 1.6, but the relative risk of suicidal ideation was about equal (1.1 for women). The main risk factors for suicidal ideation in women were low social support (OR 4.0) and frequent punishment in childhood (OR 3.7), and in men, a depressive (OR 6.5) and an anxious personality (OR 4.6). The main risk factors for suicide attempts in women were a broken home (OR 10.2) and sexual abuse/violence (OR 7.9) in childhood; in men, no multivariate analyses of suicide attempt were conducted because of insufficient statistical power. AbstractOur prospective Zurich Study found that suicidal ideation had occurred in 40.5%and suicide attempts in 6.6% of the population by age 50. Important gender differences were found in both suicidality and its risk factors. Suicide attempts were earlier and more frequent among women than among men: 70% vs 44% reported their first suicide attempt before 20.For women the relative risk of suicide attempts was 1.6, but the relative risk of suicidal ideation was about equal (1.1 for women). The main risk factors for suicidal ideation in women were low social support (OR=4.0) and frequent punishment in childhood (OR=3.7), and in men a depressive (OR=6.5) and an anxious personality (OR=4.6). The main risk factors for suicide attempts in women were a broken home (OR=10.2) and sexual abuse/violence (OR=7.9) in childhood; in men no multivariate analyses of suicide attempt were conducted because of insufficient statistical power.

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Section: Discussionsupporting

confidence: 77%

Suicidality in the prospective Zurich study: prevalence, risk factors and gender

Angst

Hengartner

Rogers

et al. 2014

Eur Arch Psychiatry Clin Neurosci

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“…Both of these findings are consistent with a wide body of research literature which identifies a significant relationship between low perceived social support (e.g., Morrison et al, 1999) and suicidality, and negative life events, such as divorce and bereavement, and suicidality (Antypa et al, 2013;Azorin et al, 2009). However, whereas the existing literature tends to cite negative life events as being significant and life-changing, such as the aforementioned divorce and bereavement, participants in the present study also recalled the ways in which minor or seemingly innocuous social events, such as a friend not returning a phone call, could trigger the downward spiral of negative thoughts.…”

Section: Discussionsupporting

confidence: 76%

“…The few studies which have focused upon social factors and suicidality in bipolar disorder have highlighted the significance of adversities during early life, such as childhood physical and sexual abuse (Alvarez et al, 2011;Carballo et al, 2008;Garno et al, 2005;Leverich et al, 2002), a family history of suicidal behaviour (Galfalvy et al, 2006;Leverich et al, 2002;MacKinnon et al, 2005;Pawlak et al, 2013), a family history of mental health problems (Lopez et al, 2001;Pawlak et al, 2013), problems with social relationships (Leverich et al, 2002;Tsai et al, 1999), and stressful life events (Antypa et al, 2013;Azorin et al, 2009).…”

Section: Introductionmentioning

confidence: 99%

A qualitative investigation into the relationships between social factors and suicidal thoughts and acts experienced by people with a bipolar disorder diagnosis

Owen

Gooding

Dempsey

et al. 2015

Journal of Affective Disorders

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This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. AbstractBackground: The prevalence rate of completed suicide in bipolar disorder is estimated to be as high as 19%. Social factors or influences, such as stigmatisation and family conflict, contribute to the development of suicidal ideation in clinical and non-clinical populations. Yet, there is a lack of studies examining suicidality from a psychosocial perspective in people who experience bipolar disorder.Method: Semi-structured interviews were used to collect qualitative data from 20 participants with bipolar disorder. The interview focused on the effects of social factors upon participants" experiences of suicidality (suicidal thoughts, feelings or behaviours). A thematic analysis was used to understand the data.Results: Social or interpersonal factors which participants identified as protective against suicidality included, 'the impact of suicide on others' and, 'reflecting on positive social experiences'. Social factors which triggered suicidal thoughts included, 'negative social experiences' and, 'not being understood or acknowledged'. Social factors which worsened suicidal thoughts or facilitated suicidal behaviour were, 'feeling burdensome," and 'reinforcing negative self-appraisals'.Limitations: Some participants had not experienced suicidal thoughts for many years and were recalling experiences which had taken place over ten years ago. The accuracy and reliability of these memories must therefore be taken into consideration when interpreting the results. Conclusions:The themes help to enhance current understanding of the ways in which social factors affect suicidality in people who experience bipolar disorder. These results highlight the importance of considering the social context in which suicidality is experienced and incorporating strategies to buffer against the effects of negative social experiences in psychological interventions which target suicide risk in bipolar disorder.

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“…Coexistence of temperaments or intrusion of a mood episode on a temperament of the opposite polarity also produces complex clinical manifestations and might lead to poor outcome. Often this poor outcome does not reflect inherent properties of the illness, but instead reflects the inability of the therapist to understand the illness and adequately plan treatment 72,[110][111][112][113][114][115][116][117]123,124,[129][130][131]133 . Temperament assessment could be especially helpful in understanding gender differences and planning treatment accordingly 128,136,140,141 .…”

Section: Discussionmentioning

confidence: 99%

“…Lifetime suicide is related (among others) to depressive or mixed polarity of first episode and cyclothymic temperament 129 .…”

Section: Clinical Issuesmentioning

confidence: 99%

The Role of Temperament in the Etiopathogenesis of Bipolar Spectrum Illness

Fountoulakis

Gonda

Koufaki

et al. 2016

Harvard Review of Psychiatry

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Bipolar disorder constitutes a challenge for clinicians in everyday clinical practice. Our knowledge concerning this clinical entity is incomplete and contemporary classification systems are unable to reflect the complexity of this disorder.. The concept of temperament which for the first time was described during antiquity constitutes a reasonable vehicle to synthesize our knowledge on how the human body works and what determines human behavior. Although it originally included philosophical and sociocultural approaches, today the biomedical model is dominant. It is possible that specific temperaments might constitute vulnerability factors, determine the clinical picture or constitute illness course modifiers and even act as a bridge between genes and clinical manifestations, thus giving birth to the concept of the bipolar spectrum with major implications for all aspects of mental health research and providing of care. More specifically it has been reported that the hyperthymic and the depressive temperaments are related to the more 'classic' bipolar disorder, while cyclothymic, anxious and irritable temperaments are related to more complex manifestations and might predict poor response to treatment, violent or suicidal behavior and high comorbidity. It seems reasonable to assume that the incorporating of the concept of temperament and the bipolar spectrum in the standard training of psychiatric residents might result in an improvement of everyday clinical practice.3

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Risk factors associated with lifetime suicide attempts in bipolar I patients: findings from a French National Cohort

Cited by 80 publications

References 32 publications

Suicidality in the prospective Zurich study: prevalence, risk factors and gender

Suicidality in the prospective Zurich study: prevalence, risk factors and gender

A qualitative investigation into the relationships between social factors and suicidal thoughts and acts experienced by people with a bipolar disorder diagnosis

The Role of Temperament in the Etiopathogenesis of Bipolar Spectrum Illness

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