Risk Factors Associated with Community-acquired CTX-M Producing Klebsiella pneumoniae Typing by Rep-PCR in Sanandaj, Iran

Ardalan, Noeman; Jamaran, Shahab; Memari, Farzam; Davari, Kambiz; Rostami, Bahareh; Ramazanzadeh, Rashid

doi:10.13005/bbra/2271

Cited by 2 publications

(2 citation statements)

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“…En otro trabajo, Ardalan y cols. (2016), emplearon la RPC-REP para demostrar que no todas las especies que producen CTX-M se originan del mismo aislado y que los genes de resistencia se han extendido entre diferentes cepas; además lograron agrupar los perfiles genéticos relacionados con diferentes factores de riesgo 37 . Nielsen y cols.…”

Section: Discussionunclassified

Caracterización molecular y detección de genes blaCTX-M grupos 1 y 9 en Klebsiella pneumoniae resistentes a ceftazidima, en un hospital de San José de Cúcuta, Colombia

Galvis

2019

Rev. chil. infectol.

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Section: Discussionunclassified

Caracterización molecular y detección de genes blaCTX-M grupos 1 y 9 en Klebsiella pneumoniae resistentes a ceftazidima, en un hospital de San José de Cúcuta, Colombia

Galvis

2019

Rev. chil. infectol.

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“…The most commonly encountered ESBLs are derived from the sulf-hydryl variable (SHV ), cefotaxime-beta lactamases (CTX), vietnam extended-spectrum β-lactamase (VEB), and Guyana extended-spectrum ß-lactamases (GES) genes (11)(12)(13)(14). Integrons are one of the mobile genetic elements, which are able to carry genes for resistance to different antibiotics.…”

Section: Introductionmentioning

confidence: 99%

Extended-Spectrum Beta-Lactamases Producing Pseudomonas aeruginosa Isolated From Patients With Ventilator Associated Nosocomial Infection

Rezai

Ahangarkani

Rafiei

et al. 2018

Arch Clin Infect Dis

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Background: Ventilator-associated infections caused by extended-spectrum beta-lactamases (ESBL)-producing Pseudomonas aeruginosa leads to severe complications. Objectives: This research evaluated ESBL-producing P. aeruginosa carrying integron class 1 and class 2 isolated from patients with ventilator-associated nosocomial infections, admitted in to the intensive care unit (ICU) of eighteen hospitals in the north of Iran. Methods: The antibiotic susceptibility test was performed using minimum inhibitory concentration (MIC). The ESBL isolates were tested by the polymerase chain reaction (PCR) for the presence or absence of CTX, VEB, SHV, GES, and integron class 1 and 2 genes. Results: Out of the total of 205 patients at the ICUs with nosocomial infections (NIs), ESBL-producing P. aeruginosa was responsible for 14.63% of NIs. The prevalence of ventilator-associated infection for ventilator-associated pneumonia (VAP) was (25 patients) 83.33%, also 16.6% (five patients) had sepsis due to VAP. Distribution of CTX, VEB, SHV, and GES genes was 13 (43.33%), four (13.33%), 26 (86.66%), and zero (0%), respectively. The strains carrying integron class 1 and class 2 were 26 (86.66%) and two (6.66%), respectively. Regarding ESBL genes, six types of strains were observed to carry these genes. Conclusions: The presence of P. aeruginosa isolates containing different ESBL genes isolated from patients admitted to ICUs of eighteen hospitals, signifies the importance of employing antimicrobial stewardship in hospitals for avoiding unnecessary antibiotics prescription for empiric therapy, especially for critically ill patients at the ICUs.

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Risk Factors Associated with Community-acquired CTX-M Producing Klebsiella pneumoniae Typing by Rep-PCR in Sanandaj, Iran

Cited by 2 publications

References 0 publications

Caracterización molecular y detección de genes blaCTX-M grupos 1 y 9 en Klebsiella pneumoniae resistentes a ceftazidima, en un hospital de San José de Cúcuta, Colombia

Caracterización molecular y detección de genes blaCTX-M grupos 1 y 9 en Klebsiella pneumoniae resistentes a ceftazidima, en un hospital de San José de Cúcuta, Colombia

Extended-Spectrum Beta-Lactamases Producing Pseudomonas aeruginosa Isolated From Patients With Ventilator Associated Nosocomial Infection

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