Risk factors assessment and a Bayesian network model for predicting ischemic stroke in patients with cardiac myxoma

Ma, Lin; Cai, Baochang; Qiao, Meng; Zhang, Fan; Fang, Li-Bo; Wang, Chaobin; Liu, Guangzhi

doi:10.3389/fcvm.2023.1128022

Cited by 2 publications

(1 citation statement)

References 43 publications

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“…The presence of supraventricular arrhythmia, irregular tumor surface, increased tumor size, and dilated atria are linked to an increased risk of embolism [ 11 ]. Additionally, tumors displaying high mobility are predictive of embolic events [ 12 ]. TTE is usually adequate for the diagnosis, showing tumor location and size, while attachment and mobility can also be assessed.…”

Section: Discussionmentioning

confidence: 99%

A polo ball in the right atrium, importance of echocardiographic characteristics of intracardiac myxomas: a case report

Hamdan,

Alam,

Kossaify

2023

J Med Case Reports

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Background Myxomas are the most prevalent type of heart tumors, mainly occurring in the left atrium, with approximately 20% of cases found in the right atrium. Timely diagnosis and appropriate management of myxomas are crucial for favorable outcomes and to minimize complications. Case presentation A 77-year-old Asian male with no significant medical history presented with intermittent trepopnea and palpitations. Physical examination revealed regular heart sounds and no other relevant findings. A transthoracic echocardiogram showed a large, round-shaped, smooth-edged mass with diameter of 86 mm, occupying most of the right atrium. Mild tricuspid flow obstruction and mild left ventricular systolic dysfunction were also observed. Cardiac tomography confirmed the size, smooth edges, and showed microcalcifications of the mass, with no invasion of surrounding tissues. Surgical intervention successfully removed the spheroid mass, leading to the alleviation of symptoms. Histopathology confirmed the myxoma nature of the mass. A comprehensive discussion based on relevant medical literature is provided, with emphasis on echocardiographic characteristics of the mass with relation to potential embolic disease. Conclusion This case shows an atypical presentation of an exceptionally large myxoma in the right atrium, resembling the size of a polo ball, in a patient presenting with supraventricular arrhythmia and trepopnea. Early diagnosis and appropriate management played a vital role in achieving a successful outcome for the patient.

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Section: Discussionmentioning

confidence: 99%

A polo ball in the right atrium, importance of echocardiographic characteristics of intracardiac myxomas: a case report

Hamdan,

Alam,

Kossaify

2023

J Med Case Reports

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A Bayesian network approach for prognostic assessment in acute mild to moderate ischaemic stroke: Insights from a Multicentre Study (Preprint)

Liu,

Mo,

Liu

et al. 2024

Preprint

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BACKGROUND Mild to moderate ischaemic stroke accounts for one-half to two-thirds of all ischaemic stroke hospitalisations worldwide, yet prognostic models to assess functional outcome after stroke remain elusive. OBJECTIVE This study aimed to identify the risk factors and develop a prognostic assessment model for short-term functional outcome in patients with acute mild-to-moderate ischaemic stroke using the Bayesian Network (BN) approach. METHODS Patients participating in a multicentre randomised controlled trial were eligible for inclusion in this study. The least absolute shrinkage and selection operator (LASSO) regression was applied to reduce the dimensionality of the data, and synthetic minority oversampling technology (SMOTE) was used to correct data imbalances. The Bayesian network model was trained using a hill-climbing algorithm to determine the optimal network structure. The area under the receiver operating characteristic curve (AUROC) and the calibration plot were used to assess model performance. RESULTS A total of 2,432 patients were included for analysis, 424（17.43%）patients had unfavorable outcome in 3-month after AIS,. The BN model identified the NIH Stroke Scale (NIHSS) score, age, C-reactive protein (CRP) levels, fasting plasma glucose (FPG), and history of stroke as significant prognostic factors. The BN model outperformed the logistic regression model in accuracy, sensitivity, and F1 score in test sets, with significant differences in the AUROC as per the DeLong test (P < 0.05). The calibration plot showed good agreement between predictions and observations in both the training and test sets. CONCLUSIONS The NIHSS score, age, CRP levels, FPG, and history of stroke are significant predictors of functional outcome in AIS patients. The BN model demonstrates superior predictive performance compared to traditional logistic regression, suggesting its potential as a valuable tool for assessing short-term prognosis in mild-moderate ischaemic stroke patients. CLINICALTRIAL The trial is registered in the Chinese Clinical Trial Registry (http://www. chictr.org.cn/, ChiCTR1900026492) on 12 October 2019.

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Risk factors assessment and a Bayesian network model for predicting ischemic stroke in patients with cardiac myxoma

Cited by 2 publications

References 43 publications

A polo ball in the right atrium, importance of echocardiographic characteristics of intracardiac myxomas: a case report

A polo ball in the right atrium, importance of echocardiographic characteristics of intracardiac myxomas: a case report

A Bayesian network approach for prognostic assessment in acute mild to moderate ischaemic stroke: Insights from a Multicentre Study (Preprint)

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