Risk Factors and Temporal Trends of Hospital-Acquired Infections (HAIs) Among HIV Positive Patients in Urban New York City Hospitals: 2006 to 2014

Tchakoute, Christophe Toukam; Liu, Jianfang; Cohen, Bevin; Larson, Elaine

doi:10.2174/1574887111666160906094140

Cited by 3 publications

(3 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…HIV attacks cells of the immune system, hindering their ability to fight infections. Consequently, HIV patients are more susceptible to bacterial, fungal, and viral infections (18)(19)(20).…”

Section: Discussionmentioning

confidence: 99%

Mortality from Infections Associated with Health Care in Patients with HIV in Paraguay

Lopez,

Aguilar,

Rios-González

2024

Med Clín Soc

View full text Add to dashboard Cite

Introduction: Few studies have evaluated HAIs in an HIV population; however, studies have suggested that patients with HIV are at a higher risk of contracting HAI because they have high rates of hospitalization and longer hospital stays. Objective: To determine mortality due to Infections Associated with Health Care in Patients with HIV in Paraguay from January to December 2018 to 2021. Methodology: This was an observational, descriptive, and cross-sectional study. The study population consisted of people over 18 years of age who died with a diagnosis of HIV infection and IAAS of both sexes during that period. The study variables were demographic, HIV-related, Baseline Viral Load, Stage of HIV infection at the time of diagnosis, Time from HIV diagnosis to death (in months), comorbidities at the time of death, microorganism isolation, presence, and location. of IAAS. Results: 93 patients with IAAS were included in the study, of which 34.4% (32) were between 20 and 29 years of age and 19.3% (18). Regarding the type of population, 79.3% (73) were in the general population, 77.6% (59) were diagnosed with AIDS, and 68.6% (59) had a baseline CD4 count of less than 200 cells/mm3. The mortality rate in 2020 was 6.7%, during 2018 it was 6.5% and in 2021 it and 6.4%. Conclusion: People with HIV, especially those who have been diagnosed in advanced stages of the disease, are more likely to develop HAIs and are related to mortality. This is due to the presence of multiple opportunistic infections and comorbidities that favor a high number of hospitalizations and longer hospital stays.

show abstract

Section: Discussionmentioning

confidence: 99%

Mortality from Infections Associated with Health Care in Patients with HIV in Paraguay

Lopez,

Aguilar,

Rios-González

2024

Med Clín Soc

View full text Add to dashboard Cite

show abstract

“…A retrospective cohort study [87] was carried out in an academic health system in New York City, which included 10,575 (697 UTIs) HIV-positive discharges from four hospitals over a period from 2006 to 2014. The rates of HAIs among HIV-infected patients are likely to be higher than those among HIV-uninfected patients; the risk factors were similar.…”

Section: Hospital-acquired Utismentioning

confidence: 99%

Urinary Tract Infection in HIV/AIDS Patients

Amaya-Tapia¹,

Ibarra-Nieto²,

Rivas³

et al. 2023

Urinary Tract Infections - New Insights

View full text Add to dashboard Cite

Urinary tract infection (UTI) is a common condition around the world, even affecting immunocompromised hosts such as people with human immunodeficiency virus (HIV) infection or acquired immuodeficiency syndrome (AIDS). Due to the anatomical conditions of the urogenital tract, women are more susceptible to UTI. Risk factors throughout life are determinants in the appearance of UTI. The frequency increases especially in women and is associated with sexual activity and pregnancy. In older adults and the elderly, again the frequency of UTI in both genders increases. In women, it is usually related at anatomical and functional sequelae due to parity and gyneco-obstetric surgeries. In old men, prostatic enlargement is an important concern. Chronic degenerative diseases such as diabetes mellitus with complications explain the high frequency of UTI in this population. Currently, the increase in violence and accidents are the leading cause of traumatic injuries with neurological damage, which leads the use of permanent urinary catheter. In patients infected with HIV/AIDS, the disease can be severe and is associated with more complications. The etiology in this population can be diverse, including fungi, parasites, and virus; antimicrobial resistance is a therapeutic challenge. This chapter is a comprehensive review of the epidemiology, pathophysiology, clinical presentation, diagnosis approach, and current treatment of UTIs in HIV/AIDS patients.

show abstract

“…[21–23] Using invasive devices, the presence of opportunistic disease, renal failure, and ICU stay are risk factors for acquiring HAI in an HIV-positive population. [24] Furthermore, there is no consensus on the most frequent HAI in HIV patients [21,25–27] and whether this population has a higher risk of acquiring HAIs caused by MDROs. [22,27]…”

Section: Introductionmentioning

confidence: 99%

Impact of human immunodeficiency virus infection on mortality of patients who acquired healthcare associated-infection in critical care unit

Lima

Borges²,

Joelsons³

et al. 2019

Medicine

View full text Add to dashboard Cite

To evaluate 30-day mortality in human immunodeficiency virus (HIV) and non-HIV patients who acquired a healthcare-associated infection (HAI) while in an intensive care unit (ICU), and to describe the epidemiological and microbiological features of HAI in a population with HIV. This was a retrospective cohort study that evaluated patients who acquired HAI during their stay in an Infectious Diseases ICU from July 2013 to December 2017 at a teaching hospital in Brazil. Data were obtained from hospital infection control committee reports and medical records. Statistical analysis was performed using SPSS and a multivariate model was used to evaluate risk factors associated with 30-day mortality. Epidemiological, clinical, and microbiological characteristics of HAI in HIV and non-HIV patients and 30-day mortality were also evaluated. Among 1045 patients, 77 (25 HIV, 52 non-HIV) patients acquired 106 HAI (31 HIV, 75 non-HIV patients). HIV patients were younger (45 vs 58 years, P = .002) and had more respiratory distress than non-HIV patients (60.0% vs 34.6%, P = .035). A high 30-day mortality was observed and there was no difference between groups (HIV, 52.0% vs non-HIV, 54.9%; P = .812). Ventilator-associated pneumonia (VAP) was more frequent in the HIV group compared with the non-HIV group (45.2% vs 26.7%, P = .063), with a predominance of Gram-negative organisms. Gram-positive agents were the most frequent cause of catheter associated-bloodstream infections in HIV patients. Although there was a high frequency of HAI caused by multidrug-resistant organisms (MDRO), no difference was observed between the groups (HIV, 77.8% vs non-HIV, 64.3%; P = .214). Age was the only independent factor associated with 30-day mortality (odds ratio [OR]: 1.05, 95% confidence interval [CI]: 1.01–1.1, P = .017), while diabetes mellitus (OR: 3.64, 95% CI: 0.84–15.8, P = .085) and the Sequential Organ-Failure Assessment (SOFA) score (OR: 1.16, 95% CI: 0.99–1.37, P = .071) had a tendency to be associated with death. HIV infection was not associated with a higher 30-day mortality in critical care patients with a HAI. Age was the only independent risk factor associated with death. VAP was more frequent in HIV patients, probably because of the higher frequency of respiratory conditions at admission, with a predominance of Gram-negative organisms.

show abstract

Risk Factors and Temporal Trends of Hospital-Acquired Infections (HAIs) Among HIV Positive Patients in Urban New York City Hospitals: 2006 to 2014

Cited by 3 publications

References 36 publications

Mortality from Infections Associated with Health Care in Patients with HIV in Paraguay

Mortality from Infections Associated with Health Care in Patients with HIV in Paraguay

Urinary Tract Infection in HIV/AIDS Patients

Impact of human immunodeficiency virus infection on mortality of patients who acquired healthcare associated-infection in critical care unit

Contact Info

Product

Resources

About