Risk Factors and Rate of Progression of CKD in Children

Kamath, Nivedita; Iyengar, Arpana; George, Nivya; Luyckx, Valérie A.

doi:10.1016/j.ekir.2019.06.004

Cited by 32 publications

(21 citation statements)

References 9 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hypertension was an important complication of renal disease among our studied cohort. Hypertension is a disease that should be diagnosed and managed promptly given its potential of life threatening complications (27). General ward physicians should be proficient in diagnosis and management of hypertension in children.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pattern of Renal and Urinary Tract Diseases Among Children Admitted to A General Ward Over One Year

Kotb

Yassin

Lotfi

et al. 2022

Pediatric Sciences Journal

View full text Add to dashboard Cite

Background: Children with renal and urinary tract diseases may require admission in general pediatric wards. Aim of the work:To identify the pattern of renal and urinary tract diseases among children admitted to general pediatric ward and their associated morbidities and mortality. Methods: Retrospective analysis of files of children with confirmed diagnosis of renal and urinary tract diseases who were admitted to a general pediatric ward, at Children Hospital, Cairo University. Results: During 12 months, 142 patients with renal or urinary tract disease were admitted to our pediatric general ward. Of them 97 (68.3%) were boys and 45 (31.7%) were girls. Their mean age was 5.1 ± 3.89 years. Of them 121 (85.2%) had isolated renal disease and 21 (14.8%) had renal affection as a part of systemic diseases. The most common diseases among those with isolated renal disease, were glomerular diseases (62 patients, 51.2%), followed by congenital anomalies of the kidney and urinary tract (33 patients, 27.3%). Different types of infection were the main cause for admission among 78 (54.9%) children. Thirty four patients (23.9%) underwent renal replacement therapy, and 26 patients suffered from poor outcome. Conclusion:Pediatricians should have the knowledge of the different presentations of renal disease in children and be trained for timely referral to the pediatric nephrologists and/or urologist. Renal diseases should be suspected in those with diseases of other systems. Infections are the commonest renal indication of admission in the general pediatric ward.

show abstract

Section: Discussionmentioning

confidence: 99%

“…General ward physicians should be proficient in diagnosis and management of hypertension in children. Hypertension is a modifiable cause for the progression of pediatric CKD (21); as the kidney is a major site for target organ damage of hypertension and hypertension could lead to progressive nephron damage (27,28).…”

Section: Discussionmentioning

confidence: 99%

Pattern of Renal and Urinary Tract Diseases Among Children Admitted to A General Ward Over One Year

Kotb

Yassin

Lotfi

et al. 2022

Pediatric Sciences Journal

View full text Add to dashboard Cite

show abstract

“…Studies from a tertiary Indian centre report higher burden of CKD comorbidities and faster rates of CKD progression compared to HIC [ 25 , 27 ]. Besides, an alarming observation from the same centre included a significant (42%) proportion of children with CKD 5 being lost to follow-up with discontinuation of care while only 20% underwent transplantation [ 28 ].…”

Section: Kidney Failure Care—the Stepping Stonementioning

confidence: 99%

Paediatric kidney transplantation in under-resourced regions—a panoramic view

Iyengar

McCulloch

2021

Pediatr Nephrol

Self Cite

View full text Add to dashboard Cite

Kidney transplantation is the ideal choice of kidney replacement therapy in children as it offers a low risk of mortality and a better quality of life. A wide variance in the access to kidney replacement therapies exists across the world with only 21% of low- and low-middle income countries (LLMIC) undertaking kidney transplantation. Pediatric kidney transplantation rates in these under-resourced regions are reported to be as low as < 4 pmcp [per million child population]. A robust kidney failure care program forms the cornerstone of a transplant program. Even the smallest transplant program entails a multidisciplinary workforce and expertise besides ensuring family commitment towards long-term care and economic burden. In general, the short-term graft survival rates from under-resourced regions are comparable to most high-income countries (HIC) and the challenge lies in the long-term outcomes. This review focuses on specific issues relevant to kidney transplants in children in under-resourced regions by highlighting limitations in the capacity and health workforce, regulatory norms, medical issues, economic burden, factors beyond financial hardship and ethical considerations relevant to these regions. Finally, the perspective of strengthening transplant programs in these regions should factor in the bigger challenges that exist in achieving the health-related sustainable development goals by 2030.

show abstract

“…Among children and ado lescents with end-stage renal failure, 48 to 79 % are hypertensive, including 20 to 70 % of individuals having uncontrolled AH [17,18]. A recent study has shown that children with uncontrolled AH have a higher risk of CKD progression than children with normal BP or controlled AH [19].…”

Section: Autonomic Disorders In Children and Adolescents With Ckd Volmentioning

confidence: 99%

Почки И Вегетативная Дисфункция У Детей И Подростков (Часть I)

Вакуленко¹

2021

KIDNEYS

View full text Add to dashboard Cite

The article discusses the mechanisms of interaction, development and progress of cardiovascular complications in children and adolescents with chronic kidney disease. The dominant role of autonomic dysfunction in the development of cardiovascular disorders is emphasized. The mechanisms are described by which an increase in the activity of sympathetic part of autonomic nervous system leads to kidney damage. Interaction of sympathetic nervous system and renin-angiotensin system during the formation of cardiovascular and kidney diseases is considered as a component of adaptive process of the body. The universal pathogenetic factor that accompanies the development of autonomic dysfunction and chronic kidney disease in children and adolescents is activation of renin-angiotensin system. The general mechanisms for the development of cardiorenal disorders determine further unidirectional approaches to the diagnosis and treatment.

show abstract

Risk Factors and Rate of Progression of CKD in Children

Cited by 32 publications

References 9 publications

Pattern of Renal and Urinary Tract Diseases Among Children Admitted to A General Ward Over One Year

Pattern of Renal and Urinary Tract Diseases Among Children Admitted to A General Ward Over One Year

Paediatric kidney transplantation in under-resourced regions—a panoramic view

Почки И Вегетативная Дисфункция У Детей И Подростков (Часть I)

Contact Info

Product

Resources

About